Physical Sciences and Mathematics Commons^™

A Computational Model For Recovery From Brain Injury, Wayne Wakeland

Systems Science Friday Noon Seminar Series

A computational simulation model calculates recovery trajectories following traumatic brain injury (TBI). Prior publications include a multi-scale framework for studying concussion and a systems-level causal loop diagram (CLD) and discussion of feedback processes. The scope of the computational model goes beyond concussion to include all severities of TBI. A set of first order ordinary differential equations and their associated parameters determines recovery trajectories. While highly speculative, the model serves to demonstrate the potential utility of computational models in this context. Much more research will be needed to create a properly supported research model that could be used for clinical trial …