Physical Sciences and Mathematics Commons^™

Characterization Of The Dimerization Domains On The Mannose-6-Phosphate/Insulin-Like Growth Factor Ii Receptor, Tyler Degener

Theses/Capstones/Creative Projects

The mannose-6-phosphate/insulin-like growth factor II (M6P/IGF2) receptor is a transmembrane protein known to sequester growth factors from the extracellular matrix. This behavior suggests a mechanism of tumor suppression. Structurally, the receptor’s extracellular region is segmented into 15 homologous repeats, which are divided further into 5 triplet domains, labelled 1-3, 4-6, 7-9, 10-12, and 13-15. What is notable about the triplets is their propensity to form dimers with triplets on a second M6P/IGF2 receptor. In fact, previous studies indicate that this protein functions optimally when dimerized. Thus, the purpose of this experiment is to characterize these domain interactions. Using a urea …

Economic And Strategic Analysis Of America's Wastewater, Jorden Hansen

Theses/Capstones/Creative Projects

Whether it be tap water from a home or bottled water from a grocery store, clean water is generally accessible in the United States. Unfortunately, this convenience deters people from learning about the complex processes that make this luxury possible.

Awareness of the natural water cycle is widespread, as the simplest version is taught in grade school. It illustrates the flow of water as it changes state (liquid, to solid, to gas) in the environment. Not so commonly known is the urban water cycle which manifests residential daily use with the revolution of water. The urban water cycle is a …

Estimation Of Evapotranspiration And Other Water Budget Factors At Glacier Creek Preserve, Kian Paul Mcintosh

Theses/Capstones/Creative Projects

A water budget of a watershed consists of the inputs and outputs of water to and from it, including precipitation, change in water storage, surface water flow, and evapotranspiration. Water budget estimates are of high importance as a result of increasing demand due to population growth and other factors. Improving estimate accuracy and precision of evapotranspiration and runoff to streams allows scientists to better determine the true availability of water for human and conservation use. At Glacier Creek Preserve, 6.5% of the incoming precipitation left the preserve as discharge from the stream and 95.9% of the incoming precipitation was lost …

Grounding Size Predictions For Answer Set Programs, Nicholas Hippen

Student Work

Answer set programming is a declarative programming paradigm geared towards solving difficult combinatorial search problems. Logic programs under answer set semantics can typically be written in many different ways while still encoding the same problem. These different versions of the program may result in diverse performances. Unfortunately, it is not always easy to identify which version of the program performs the best, requiring expert knowledge on both answer set processing and the problem domain. More so, the best version to use may even vary depending on the problem instance. One measure that has been shown to correlate with performance is …

Examining Electrochemical Properties Of O-Quinone And Sulfur Adducts Using Bisphenol A-3,4-Quinone Platform, Barbara Mullen

Theses/Capstones/Creative Projects

o-Quinones are toxic electrophiles that can disrupt cellular macromolecules. Whether endogenous or xenobiotic, o-quinones are reactive compounds that are difficult to isolate. This work uses the o-quinone of bisphenol(BPA), bisphenol A-3,4-quinone(BPAQ), which can be efficiently synthesized and isolated, to study the electrochemical properties of o-quinones and their sulfur adducts in order to understand their metabolic fate. Cyclic voltammetry and equilibrium analysis were used to determine the relative oxidation potential of the BPA catechol and adducts, formed by reacting glutathione(GSH) and N-acetylcysteine(NAC) with BPAQ. BPAQ-sulfur adducts with 5-position substitution displayed lower oxidation potentials when compared to the …

Grant Anon Minigames Extension, Justin Robbins

Theses/Capstones/Creative Projects

The Grant Anon system was designed to be a casualized version of the real-time strategy genre, a genre usually known for its difficulty and competitiveness because of Starcraft II, the most popular game in the genre. Grant Anon was designed as part of a capstone project, and this report details the extension that was created to add an additional element designed to make it easier for any player to enjoy Grant Anon: minigames. These minigames serve to reduce the skill needed to participate effectively in Grant Anon. This is accomplished by providing an alternative means of gaining an advantage over …

Cooperative Signaling Behavior: Signals For Open Source Project Health, Georg John Peter Link

Information Systems and Quantitative Analysis Theses, Dissertations, and Student Creative Activity

The core contribution is a critique of signaling theory from investigating cooperative signaling behavior in the context of organizational engagement with open source projects. Open source projects display signals of project health which are used by organizations. Projects and organizations engage in cooperative signaling behavior when they work together to create signals. Signaling theory is critiqued in the cooperative context of organizational engagements with open source projects by describing how cooperative signaling behavior occurs in three processes: identifying, evaluating, and filtering new signals. The contribution is informed through engaged field research and interviews, which are presented as a thick description …

Processing Narratives By Means Of Action Languages, Craig Olson

Computer Science Theses, Dissertations, and Student Creative Activity

In this work we design a narrative understanding system Text2ALM that can be used in Question Answering domains. System Text2ALM utilizes an action language 𝒜ℒℳ to perform inferences on complex interactions of events described in narratives. The methodology that Text2ALM follows in its implementation was originally outlined by Yuliya Lierler, Daniela Inclezan, and Michael Gelfond in 2017 via a manual process, and this work serves as a proof of concept in a large-scale environment. Our system automates the conversion of a narrative to an 𝒜ℒℳ model containing facts about the narrative. We make use of the VerbNet lexicon that we …