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Nephrotoxic Contaminants In Drinking Water And Urine, And Chronic Kidney Disease In Rural Sri Lanka, Tewodros Rango, Marc Jeuland, Herath Manthrithilake, Peter G. Mccornick

Daugherty Water for Food Global Institute: Faculty Publications

Chronic kidney disease of unknown (“u”) cause (CKDu) is a growing public health concern in Sri Lanka. Prior research has hypothesized a link with drinking water quality, but rigorous studies are lacking. This study assesses the relationship between nephrotoxic elements (namely arsenic (As), cadmium (Cd), lead (Pb), and uranium (U)) in drinking water, and urine samples collected from individuals with and/or without CKDu in endemic areas, and from individuals without CKDu in nonendemic areas. All water samples—from a variety of source types (i.e., shallow and deep wells, springs, piped, and surface water)—contained extremely low concentrations of nephrotoxic elements, and all …