Physical Sciences and Mathematics Commons^™

Application Of The Tissue Residue Approach In Ecological Risk Assessment, Steven P. Bradbury, Keith G. Sappington, Todd S. Bridges, Russell J. Erickson, A. Jan Hendriks, Roman P. Lanno, James P. Meador, David R. Mount, Mike H. Salazar, Doug J. Spry

Steven P. Bradbury

The objective of this work is to present a critical review of the application of the tissue residue approach (TRA) in ecological risk and/or impact assessment (ERA) of chemical stressors and environmental criteria development. A secondary goal is to develop a framework for integrating the TRA into ecological assessments along with traditional, exposure concentration-based assessment approaches. Although widely recognized for its toxicological appeal, the utility of the TRA in specific applications will depend on numerous factors, such as chemical properties, exposure characteristics, assessment type, availability of tissue residue-response data, and ability to quantify chemical exposure. Therefore, the decision to use …