Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
Increased Yields And Simplified Purification With A Second-Generation Cobalt Catalyst For The Oxidative Formation Of Trans-Thf Rings., Cory Palmer, Nicholas A Morra, Andrew C Stevens, Barbora Bajtos, Ben P Machin, Brian L Pagenkopf
Increased Yields And Simplified Purification With A Second-Generation Cobalt Catalyst For The Oxidative Formation Of Trans-Thf Rings., Cory Palmer, Nicholas A Morra, Andrew C Stevens, Barbora Bajtos, Ben P Machin, Brian L Pagenkopf
Chemistry Publications
The synthesis of a second-generation cobalt catalyst for the formation of trans-THF products via the Mukaiyama aerobic oxidative cyclization is reported. Two procedures have been developed with the new water-soluble catalyst that give superior yields and greatly simplify purification compared to the previous catalysts.
Synthesis Of Tetrahydroisoquinocarbazoles Via C-2 Alkylation Of Indoles With 2-Alkoxycyclopropanoate Esters., Barbora Bajtos, Brian L Pagenkopf
Synthesis Of Tetrahydroisoquinocarbazoles Via C-2 Alkylation Of Indoles With 2-Alkoxycyclopropanoate Esters., Barbora Bajtos, Brian L Pagenkopf
Chemistry Publications
A concise method for the synthesis of several tetrahydroisoquinocarbazole derivatives is reported, where the core is prepared in six steps from tryptophol in 51% overall yield. The pentacyclic analogs are constructed via a dipolar C-2 alkylation of a 3-substituted indole with a 2-alkoxycyclopropanoate ester and a SmBr(2)-HMPA mediated ketyl-alkene ring closure.