Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Physical Sciences and Mathematics
A Novel And Stereospecific Synthesis Of Conduritol-E Via Cyclohexa-3,5-Diene-1,2-Diol, Ahmet Maras, Hasan Secen, Yasar Sütbeyaz, Metin Balci
A Novel And Stereospecific Synthesis Of Conduritol-E Via Cyclohexa-3,5-Diene-1,2-Diol, Ahmet Maras, Hasan Secen, Yasar Sütbeyaz, Metin Balci
Turkish Journal of Chemistry
Conduritol-E was synthesized starting from cyclohexa-3,5-diene-1,2-diol {\bf 1a} in six steps. Acetylation of the diol {\bf 1a} followed by bromination gave (2\alpha/1\beta, \,\, 3\beta, \,\, 4\beta)-1,2-dibromo-2,3- diacetoxy- 5-cyclohexene {\bf 3} as main product. KMnO_{4}-hydoxylation of the dibromide {\bf 3} followed by acetylation, Zn-elimination and hydrolysis afforded conduritol-E {\bf 5a}.