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Electrical Conductivity Of Thin Lecithin-Cholesterol Membranes Due To 2,4-D, 2,4-Db, 2,4,5-T And 2,4-Dcp, Malkanthi Paulis

Dissertations and Theses

The effect of the following pesticides on DC electrical conductivity of lecithin-cholesterol membranes has been studied: endothall, paraquat, diquat, 2,4-D, 2,4-DB, 2,4,5-T, 2,4-DCP. It has been found that the ions of endothall, paraquat and diquat are essentially membrane impermeable and that they do not bind to the membrane surface. In contrast, 2,4-D, 2,4-DB, 2,4,5-T and 2,4-DCP induce electrical conductivity in lecithincholesterol membranes and in addition they also cause an increase in the nonactin-K⁺ membrane conductivity.

The compounds 2,4-D, 2,4-DB, 2,4,5-T and 2,4-DCP basically behave as class II uncouplers. The kinetic scheme of charge transfer across the membrane, based on …