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Mathematical modeling

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Applying Mathematical Modeling To The Study Of Family Systems, Dahlia Maxwell Apr 2024

Applying Mathematical Modeling To The Study Of Family Systems, Dahlia Maxwell

Theses and Dissertations

Mathematical modeling provides a powerful framework for insight into current scientific theories as well as hypothesis generation for further research. Despite its undeniable potential to enrich scientific advancement, the application of mathematical modeling remains conspicuously scarce in the field of family science. The complexity inherent in family dynamics, coupled with the intricate interplay of emotions in the individual, underscores the necessity of a robust analytical approach. Addressing this critical gap in the literature, this thesis introduces a sophisticated mathematical model of family dynamics integrating essential elements from family systems theory, emotion dynamics, and appraisal theory. The model is implemented as …


Modeling The Opioid Crisis In Virginia: A Differential Equations Model Assessing The Impact Of Medication-Assisted Treatment On The Addicted Population, Maniha Zehra Akram Jan 2024

Modeling The Opioid Crisis In Virginia: A Differential Equations Model Assessing The Impact Of Medication-Assisted Treatment On The Addicted Population, Maniha Zehra Akram

Honors Theses

The opioid epidemic is prevalent in countless communities throughout the United States and has yet to be mitigated. Treatments for OUD (opioid use disorder) include Medication-Assisted Treatment (MAT) and treatment without medication (non-MAT), with the former being judged as more effective in terms of lower relapse rates, death rates, and criminal activity (U.S. Food & Drug Administration, 2023; SAMHSA, 2024). Motivated by the promising research on MAT, this paper models the relationship

between the treatment and addicted populations using a system of ordinary differential equations. In addition to producing closed-form equilibrium solutions, the model leads to the conclusion that expanding …


An Integrated Experimental And Modeling Approach To Design Rotating Algae Biofilm Reactors (Rabrs) Via Optimizing Algae Biofilm Productivity, Nutrient Recovery, And Energy Efficiency, Gerald Benjamin Jones May 2023

An Integrated Experimental And Modeling Approach To Design Rotating Algae Biofilm Reactors (Rabrs) Via Optimizing Algae Biofilm Productivity, Nutrient Recovery, And Energy Efficiency, Gerald Benjamin Jones

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Microalgae biofilms have been demonstrated to recover nutrients from wastewater and serve as biomass feedstock for bioproducts. However, there is a need to develop a platform to quantitatively describe microalgae biofilm production, which can provide guidance and insights for improving biomass areal productivity and nutrient uptake efficiency. This paper proposes a unified experimental and theoretical framework to investigate algae biofilm growth on a rotating algae biofilm reactor (RABR). The experimental laboratory setups are used to conduct controlled experiments on testing environmental and operational factors for RABRs. We propose a differential-integral equation-based mathematical model for microalgae biofilm cultivation guided by laboratory …


Mathematical Modeling: Finite Element Analysis And Computations Arising In Fluid Dynamics And Biological Applications, Jorge Reyes May 2023

Mathematical Modeling: Finite Element Analysis And Computations Arising In Fluid Dynamics And Biological Applications, Jorge Reyes

UNLV Theses, Dissertations, Professional Papers, and Capstones

It is often the case when attempting to capture real word phenomena that the resulting mathematical model is too difficult and even not feasible to be solved analytically. As a result, a computational approach is required and there exists many different methods to numerically solve models described by systems of partial differential equations. The Finite Element Method is one of them and it was pursued herein.This dissertation focuses on the finite element analysis and corresponding numerical computations of several different models. The first part consists of a study on two different fluid flow models: the main governing model of fluid …


Stochastic Modeling Of Flows In Membrane Pore Networks, Binan Gu Aug 2022

Stochastic Modeling Of Flows In Membrane Pore Networks, Binan Gu

Dissertations

Membrane filters provide immediate solutions to many urgent problems such as water purification, and effective remedies to pressing environmental concerns such as waste and air treatment. The ubiquity of applications gives rise to a significant amount of research in membrane material selection and structural design to optimize filter efficiency. As physical experiments tend to be costly, numerical simulation and analysis of fluid flow, foulant transport and geometric evolution due to foulant deposition in complex geometries become particularly relevant. In this dissertation, several mathematical modeling and analytical aspects of the industrial membrane filtration process are investigated. A first-principles mathematical model for …


Developing Confidence And Interest In Teaching Relevant Mathematical Modeling Lessons, Jacy Beck Aug 2022

Developing Confidence And Interest In Teaching Relevant Mathematical Modeling Lessons, Jacy Beck

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

What is mathematical modeling and how can inservice and pre-service teachers develop the skills and competencies necessary to increase confidence and interest in teaching relevant mathematical modeling lessons? Mathematical modeling is “the process of choosing and using appropriate mathematics and statistics to analyze empirical situations, to understand them better, and to improve decisions” (CSSM, 2010, p. 72). By providing students with an opportunity to engage in relevant mathematical modeling prompts, we provide them with transferable skills and knowledge. The aim of this paper will be to provide insight into the relevance of teaching mathematical modeling, provide resources for integrating modeling …


A New Sir Model With Mobility., Ciana Applegate Aug 2022

A New Sir Model With Mobility., Ciana Applegate

Electronic Theses and Dissertations

In this paper, a mobility-based SIR model is built to understand the spread of the pandemic. A traditional SIR model used in epidemiology describes the transition of particles among states, such as susceptible, infected, and recovered states. However, the traditional model has no movement of particles. There are many variations of SIR models when it comes to the factor of mobility, the majority of studies use mobility intensity or population density as a measure of mobility. In this paper, a new dynamical SIR model, including the spatial motion of three-type particles, is constructed and the long-time behavior of the first …


Modeling The Effect Of Human Behavior On Disease Transmission, Katie Yan Apr 2022

Modeling The Effect Of Human Behavior On Disease Transmission, Katie Yan

Mathematics and Statistics Theses

Many infectious disease models build upon the classical Susceptible-Infected-Recovered (SIR) model. The SIR model is a compartmental model that is used to model disease transmission throughout a population. The SIR model and its variations often focus on the transmission of disease but rarely include behavioral or informational components that explore how the perception of a disease influences transmission. In this thesis we propose a six compartment SIR model that segments the classical SIR model based on knowledge of information to explore the sharing of information and its ability to increase and decrease transmission. We designate these two model states as …


Stabilizing Controlled Systems In The Presence Of Time-Delays, Isaac Becker Pardo Apr 2022

Stabilizing Controlled Systems In The Presence Of Time-Delays, Isaac Becker Pardo

Theses and Dissertations

A dynamical system's state evolves over time, and when the system stays near a particular state this state is known as a stable state of the system. Through control methods, dynamical systems can be manipulated such that virtually any state can be made stable. Although most real systems evolve continuously in time the application of digital control methods to these systems is inherently discrete. States are sampled (with sensors) and fed back into the system in discrete-time to determine the input needed to control the continuous system. Additionally, dynamical systems often experience time delays. Some examples of time delays are …


Mathematical Models Of Infection Prevention Programs In Hospital Settings, Kelly A. Reagan Jan 2022

Mathematical Models Of Infection Prevention Programs In Hospital Settings, Kelly A. Reagan

Theses and Dissertations

Hospitals play a vital role in providing for the healthcare needs of a community. Patients can develop hospital-acquired infections (HAIs) during their hospitalization due to exposure to foreign bacteria, viruses, and fungi. Infection prevention programs target and reduce HAIs, but implementing the infection prevention programs often comes with a cost. The goal of my research is to use mathematical models to quantify the impact of infection prevention programs on cases of HAIs and total healthcare costs. First, I use a Markov chain model to quantify how one infection prevention program reduces general HAIs in the hospital. Then, I calculate the …


Modeling Dewetting, Demixing, And Thermal Effects In Nanoscale Metal Films, Ryan Howard Allaire Aug 2021

Modeling Dewetting, Demixing, And Thermal Effects In Nanoscale Metal Films, Ryan Howard Allaire

Dissertations

Thin film dynamics, particularly on the nanoscale, is a topic of extensive interest. The process by which thin liquids evolve is far from trivial and can lead to dewetting and drop formation. Understanding this process involves not only resolving the fluid mechanical aspects of the problem, but also requires the coupling of other physical processes, including liquid-solid interactions, thermal transport, and dependence of material parameters on temperature and material composition. The focus of this dissertation is on the mathematical modeling and simulation of nanoscale liquid metal films, which are deposited on thermally conductive substrates, liquefied by laser heating, and subsequently …


Modeling And Design Optimization For Membrane Filters, Yixuan Sun Aug 2021

Modeling And Design Optimization For Membrane Filters, Yixuan Sun

Dissertations

Membrane filtration is widely used in many applications, ranging from industrial processes to everyday living activities. With growing interest from both industrial and academic sectors in understanding the various types of filtration processes in use, and in improving filter performance, the past few decades have seen significant research activity in this area. Experimental studies can be very valuable, but are expensive and time-consuming, therefore theoretical studies offer potential as a cost-effective and predictive way to improve on current filter designs. In this work, mathematical models, derived from first principles and simplified using asymptotic analysis, are proposed for: (1) pleated membrane …


A Computational Investigation Of The Biophysical Mechanisms Underlying Thermotaxis In The Afd Neurons Of Caenorhabditis Elegans, Zachary Mobille Mar 2021

A Computational Investigation Of The Biophysical Mechanisms Underlying Thermotaxis In The Afd Neurons Of Caenorhabditis Elegans, Zachary Mobille

Theses and Dissertations

Thermotaxis in the nematode Caenorhabditis elegans (C. elegans) is studied at the cellular scale of the amphid finger-like ciliated (AFD) neurons, which have previously been shown to be essential for thermoreception. The voltage and calcium signals of AFD during temperature stimuli are described with ordinary differential equations. The primary calcium model is a modified version of that published by Kuramochi and Doi in 2017 to explain the calcium responses of the chemosensitive amphid single-ciliated right (ASER) neuron to fluctuations in extracellular salt concentration. To account for the effects of temperature, changes to the stimuli conditions under which inactivation takes place …


Making Real-World Connections In High School Mathematics: The Effectiveness Of A Professional Development Program In Changing Teachers’ Knowledge, Beliefs, And Practices, Thad Ludlam Wilhelm Jan 2020

Making Real-World Connections In High School Mathematics: The Effectiveness Of A Professional Development Program In Changing Teachers’ Knowledge, Beliefs, And Practices, Thad Ludlam Wilhelm

Wayne State University Dissertations

The study aimed to assess the impact of a professional development workshop at changing secondary mathematics teachers’ knowledge, beliefs, and practices related to real-world applications of algebra. It also addressed gaps in the research literature related to teacher knowledge of how algebra is used by professionals in non-academic settings and their beliefs about the relevance of algebra to their students’ lives. The observational study employed mixed methods. Principal components analysis was conducted on responses to an online questionnaire. Pre-test vs. post-test comparisons were made for workshop participants. Treatment vs. control comparisons were also made using a nationally representative random sample …


Dimension-Breaking For Traveling Waves In Interfacial Flows, Matthew W. Seiders Aug 2019

Dimension-Breaking For Traveling Waves In Interfacial Flows, Matthew W. Seiders

Theses and Dissertations

Fluid flow models in two spatial dimensions with a one-dimensional interface are known to support overturned traveling solutions. Computational methods of solving the two-dimensional problem are well developed, even in the case of overturned waves. The three-dimensional problem is harder for three prominent reasons. First, some formulations of the two-dimensional problem do not extend to three-dimensions. The technique of conformal mapping is a prime example, as it is very efficient in two dimensions but does not have a three-dimensional equivalent. Second, some three-dimensional models, such as the Transformed Field Expansion method, do not allow for overturned waves. Third, computational time …


Examining Students’ Covariational Reasoning Through Mathematical Modeling Activities Embedded In The Context Of The Greenhouse Effect, Debasmita Basu Aug 2019

Examining Students’ Covariational Reasoning Through Mathematical Modeling Activities Embedded In The Context Of The Greenhouse Effect, Debasmita Basu

Theses, Dissertations and Culminating Projects

The greenhouse effect is one of the most pressing environmental as well as social issues of the present age. In news media and weather reports, most of the essential information about the phenomenon is expressed in forms of graphs and pictures. However, the interpretation of such graphs is challenging for students; they often focus on the shape of the graphs, overlooking the covariational relationships between the concerned quantities. Building on the framework of critical mathematics literacy and social justice mathematics, in this study I aimed to explore the power of dynamic mathematical modeling activities for engaging students in covariational reasoning …


Mathematical Modeling Of Type 1 Diabetes, Gianna Wu Jan 2019

Mathematical Modeling Of Type 1 Diabetes, Gianna Wu

HMC Senior Theses

Type 1 Diabetes (T1D) is an autoimmune disease where the pancreas produces little to no insulin, which is a hormone that regulates blood glucose levels. This happens because the immune system attacks (and kills) the beta cells of the pancreas, which are responsible for insulin production. Higher levels of glucose in the blood could have very negative, long term effects such as organ damage and blindness.

To date, T1D does not have a defined cause nor cure, and research for this disease is slow and difficult due to the invasive nature of T1D experimentation. Mathematical modeling provides an alternative approach …


Simulation And Modeling Of High Energy Laser-Induced Droplet Shattering In Clouds, Andrew P. Lawrence Mar 2018

Simulation And Modeling Of High Energy Laser-Induced Droplet Shattering In Clouds, Andrew P. Lawrence

Theses and Dissertations

The process of a megawatt laser passing through a cloud is modeled. Specifically, the potential for droplet shattering is explored as a method for clearing a path through a cloud through which a second laser may be sent unobstructed. The paraxial approximation, an approximation to Maxwell's equations, is used to model the beam propagation. The simplified cloud model has assumed a distribution of pure, timescale restricted, droplets evenly distributed with uniform radius and initial temperature. All of the radiative heating is assumed to heat the droplet, neglecting radius change and vaporization based upon characteristic time scales. A 1+1 dimensional model …


Mathematical Models Of Mosquito Populations, Hanna Reed Jan 2018

Mathematical Models Of Mosquito Populations, Hanna Reed

Honors Undergraduate Theses

The intent of this thesis is to develop ordinary differential equation models to better understand the mosquito population. We first develop a framework model, where we determine the condition under which a natural mosquito population can persist in the environment. Wolbachia is a bacterium which limits the replication of viruses inside the mosquito which it infects. As a result, infecting a mosquito population with Wolbachia can decrease the transmission of viral mosquito-borne diseases, such as dengue. We develop another ODE model to investigate the invasion of Wolbachia in a mosquito population. In a biologically feasible situation, we determine three coexisting …


Modeling Public Opinion, Arden Baxter Jan 2018

Modeling Public Opinion, Arden Baxter

Honors Program Theses

The population dynamics of public opinion have many similarities to those of epidemics. For example, models of epidemics and public opinion share characteristics like contact rates, incubation times, and recruitment rates. Generally, epidemic dynamics have been presented through epidemiological models. In this paper we adapt an epidemiological model to demonstrate the population dynamics of public opinion given two opposing viewpoints. We find equilibrium solutions for various cases of the system and examine the local stability. Overall, our system provides sociological insight on the spread and transition of a public opinion.


On Honey Bee Colony Dynamics And Disease Transmission, Matthew I. Betti Aug 2017

On Honey Bee Colony Dynamics And Disease Transmission, Matthew I. Betti

Electronic Thesis and Dissertation Repository

The work herein falls under the umbrella of mathematical modeling of disease transmission. The majority of this document focuses on the extent to which infection undermines the strength of a honey bee colony. These studies extend from simple mass-action ordinary differential equations models, to continuous age-structured partial differential equation models and finally a detailed agent-based model which accounts for vector transmission of infection between bees as well as a host of other influences and stressors on honey bee colony dynamics. These models offer a series of predictions relevant to the fate of honey bee colonies in the presence of disease …


Network Modeling Of Infectious Disease: Transmission, Control And Prevention, Christina M. Chandler May 2017

Network Modeling Of Infectious Disease: Transmission, Control And Prevention, Christina M. Chandler

Honors College Theses

Many factors come into play when it comes to the transmission of infectious diseases. In disease control and prevention, it is inevitable to consider the general population and the relationships between individuals as a whole, which calls for advanced mathematical modeling approaches.

We will use the concept of network flow and the modified Ford-Fulkerson algorithm to demonstrate the transmission of infectious diseases over a given period of time. Through our model one can observe what possible measures should be taken or improved upon in the case of an epidemic. We identify key nodes and edges in the resulted network, which …


Comparison Of The Regulatory Dynamics Of Related Small Gene Regulatory Networks That Control The Response To Cold Shock In Saccharomyces Cerevisiae, Natalie Williams May 2017

Comparison Of The Regulatory Dynamics Of Related Small Gene Regulatory Networks That Control The Response To Cold Shock In Saccharomyces Cerevisiae, Natalie Williams

Honors Thesis

The Dahlquist Lab investigates the global, transcriptional response of Sacchromyces cerevisiae, baker’s yeast, to the environmental stress of cold shock, using DNA microarrays for the wild type strain and strains deleted for a particular regulatory transcription factor. Gene regulatory networks (GRNs) consist of transcription factors (TF), genes, and the regulatory connections between them that control the resulting mRNA and protein expression levels. We use mathematical modeling to determine the dynamics of the GRN controlling the cold shock response to determine the relative influence of each transcription factor in the network. A family of GRNs has been derived from the …


From Random To Organized: The Architecture Of Neural Networks During Development, Avery Isabella Morris Jan 2017

From Random To Organized: The Architecture Of Neural Networks During Development, Avery Isabella Morris

Senior Projects Fall 2017

The brain is constantly changing during development as a result of various stimuli: memories, language, visual patterns and other sensory information. As a result, networks need to have specific learning rules to function being both plastic and stable. In this project, I’ve constructed a mathematical model based on a biological neural network during development. I’ve written differential equations to describe these specific learning rules as well as methods of visual input to the network. I’ve changed my model, using Euler’s method, to create a discrete-time version of this biological phenomenon to implement on the computer. I’ve successfully coded this, using …


Revisions To Rainfall Intensity Algorithms In Przm5.0 To Improve Estimates Of Off-Field Runoff, Eroded Sediment And Pesticide Mass, Tammara Levey Estes Jan 2017

Revisions To Rainfall Intensity Algorithms In Przm5.0 To Improve Estimates Of Off-Field Runoff, Eroded Sediment And Pesticide Mass, Tammara Levey Estes

LSU Doctoral Dissertations

The Environmental Protection Agency (EPA) model Pesticide Root Zone Model, version 5.0 (PRZM5.0) is used to estimate off-field loadings of pesticide concentrations in runoff and eroded sediment. Climate change has resulted in an increase in rainfall intensity patterns for much of the United States. This change impacts off-field runoff and eroded sediment as well as off-field pesticide loads from agricultural fields. Thus, the PRZM5.0 EPA “lookup” table for runoff curve numbers and the internal algorithm for eroded sediment estimation have become outdated since both temporal and geographical conditions have changed. This research presents (1) a revised method for estimating runoff …


Is Metabolism Goal-Directed? Investigating The Validity Of Modeling Biological Systems With Cybernetic Control Via Omic Data, Frank T. Devilbiss Apr 2016

Is Metabolism Goal-Directed? Investigating The Validity Of Modeling Biological Systems With Cybernetic Control Via Omic Data, Frank T. Devilbiss

Open Access Dissertations

Cybernetic models are uniquely juxtaposed to other metabolic modeling frameworks in that they describe the time-dependent regulation of cellular reactions in terms of dynamic "metabolic goals." This approach contrasts starkly with purely mechanistic descriptions of metabolic regulation which seek to explain metabolic processes in high resolution — a clearly daunting undertaking. Over a span of three decades, cybernetic models have been used to predict metabolic phenomena ranging from resource consumption in mixed-substrate environments to intracellular reaction fluxes of intricate metabolic networks. While the cybernetic approach has been validated in its utility for the prediction of metabolic phenomena, its central feature, …


Modeling The Extent Of Virus Removal In Waste Stabilization Ponds To Support Reuse Of Wastewater, Kelly James Vannoy Mar 2016

Modeling The Extent Of Virus Removal In Waste Stabilization Ponds To Support Reuse Of Wastewater, Kelly James Vannoy

USF Tampa Graduate Theses and Dissertations

Waste stabilization ponds (WSPs) are one of the most prevalent types of domestic wastewater treatment technologies employed worldwide, and global stressors such as urbanization, population growth, climate change, and water scarcity have increased the demand for reusing treated wastewater. The safe reuse of treated wastewater in agriculture can ease water scarcity, aid in food production, and reduce environmental degradation from the discharge of wastewater effluent to surface waters. The ability to predict virus concentrations in wastewater effluent is an important criterion for determining whether wastewater is suitable for discharge to the environment or for reuse in agriculture. However, many uncertainties …


Modeling Of Piezoelectric Traveling Wave Rotary Ultrasonic Motors With The Finite Volume Method, Ivan Arturo Renteria Marquez Jan 2016

Modeling Of Piezoelectric Traveling Wave Rotary Ultrasonic Motors With The Finite Volume Method, Ivan Arturo Renteria Marquez

Open Access Theses & Dissertations

In 1983 Toshiiku Sashida developed a new motor concept called Piezoelectric Traveling Wave Rotary Ultrasonic Motor (PTRUSM). The advantages of these motors include high torque at low speed, absence of a generated magnetic field, and high potential for miniaturization. Unfortunately PTRUSMs have some disadvantages that limit the areas of applications for these types of motors. The disadvantages are a short operating life (about 1000 hours), small output power, and the need of a complex motor controller.

On one hand, these motors have been used in satellites, mobile phones, photocopiers, robotic arms, telescopes, automobiles, and camera autofocusing. On the other hand, …


Mechanisms For Social Influence, Jeremy David Auerbach Aug 2015

Mechanisms For Social Influence, Jeremy David Auerbach

Masters Theses

Throughout the thesis, I study mathematical models that can help explain the dependency of social phenomena in animals and humans on individual traits. The first chapter investigates consensus building in human groups through communication of individual preferences for a course of action. Individuals share and modify these preferences through speaker listener interactions. Personality traits, reputations, and social networks structures effect these modifications and eventually the group will reach a consensus. If there is variation in personality traits, the time to reach consensus is delayed. Reputation models are introduced and explored, finding that those who can best estimate the average initial …


Course Proposal For A Mathematical Modeling Course In A High School Curriculum, Thomas P. Marlowe Jul 2015

Course Proposal For A Mathematical Modeling Course In A High School Curriculum, Thomas P. Marlowe

Masters Essays

In the winter of 2015, I will be piloting a course on mathematical modeling at Hawken School, an independent high school in Gates Mills, OH. As I develop all elements of this course, such as lesson plans, assessments, and rubrics, I will be mindful of factors such as the newly adopted Common Core mathematics standards, the variety of student backgrounds in such a course, and how various mathematical societies and organizations such as SIAM, MAA, and COMAP can help in implementing it. However, there is one basic question driving my interest in and design of this course: “when am I …