Physical Sciences and Mathematics Commons^™

Assessment Of Internationalised Domain Name Homograph Attack Mitigation, Peter Hannay, Christopher Bolan

Australian Information Security Management Conference

With the advent of internationalised domains the threat posed by non-english character sets has eventuated. Whilst this phenomenon remains well known in the development and internet industry the actual implementations of popular applications have been tested to determine their resilience to homograph based attack. The research found that most provided features that overcome such attacks, but there remain a few notable exceptions. Should an attacker take advantage of such oversights a victim would likely not be able to spot a fraudulent site or email and thus provide a perfect platform for subsequent attack.

Challenges In Improving Information Security Practice In Australian General Practice, Donald C. Mcdermid, Rachel J. Mahncke, Patricia A. Williams

Australian Information Security Management Conference

The status of information security in Australian medical general practice is discussed together with a review of the challenges facing small practices that often lack the technical knowledge and skill to secure patient information by themselves. It is proposed that an information security governance framework is required to assist practices in identifying weaknesses and gaps and then to plan and implement how to overcome their shortcomings through policies, training and changes to processes and management structure.

Measuring Information Security Governance Within General Medical Practice, Rachel J. Mahncke, Donald C. Mcdermid, Patricia A. Williams

Australian Information Security Management Conference

Information security is becoming increasingly important within the Australian general medical practice environment as legal and accreditation compliance is being enforced. Using a literature review, approaches to measuring information security governance were analysed for their potential suitability and use within General Practice for the effective protection of confidential information. The models, frameworks and guidelines selected were analysed to evaluate if they were Key Performance Indicator (KPI), or process driven; whether the approach taken was strategic, tactical or operational; and if governance or management assessment tools were presented. To measure information security governance, and be both effective and practical, the approach …

Survival Analysis With Error-Prone Time-Varying Covariates: A Risk Set Calibration Approach, Xiaomei Liao, David M. Zucker, Yi Li, Donna Spiegelman

Harvard University Biostatistics Working Paper Series

No abstract provided.

A Privacy Framework For Mobile Health And Home-Care Systems, David Kotz, Sasikanth Avancha, Amit Baxi

Dartmouth Scholarship

In this paper, we consider the challenge of preserving patient privacy in the context of mobile healthcare and home-care systems, that is, the use of mobile computing and communications technologies in the delivery of healthcare or the provision of at-home medical care and assisted living. This paper makes three primary contributions. First, we compare existing privacy frameworks, identifying key differences and shortcomings. Second, we identify a privacy framework for mobile healthcare and home-care systems. Third, we extract a set of privacy properties intended for use by those who design systems and applications for mobile healthcare and home-care systems, linking them …

2009 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Michael Schwartz Ph.D.

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Michael Schwartz was the honored guest.

Mpcs: Mobile-Based Patient Compliance System For Chronic Illness Care, Guanling Chen, Bo Yan, Minho Shin, David Kotz, Ethan Burke

Dartmouth Scholarship

More than 100 million Americans are currently living with at least one chronic health condition and expenditures on chronic diseases account for more than 75 percent of the $2.3 trillion cost of our healthcare system. To improve chronic illness care, patients must be empowered and engaged in health self-management. However, only half of all patients with chronic illness comply with treatment regimen. The self-regulation model, while seemingly valuable, needs practical tools to help patients adopt this self-centered approach for long-term care. \par In this position paper, we propose Mobile-phone based Patient Compliance System (MPCS) that can reduce the time-consuming and …

A Comparison Of Frequentist And Bayesian Approaches To The Estimation Of Long-Stay Per-Diems, Jeff Hatcher, Jason M. Sutherland

Dartmouth Scholarship

Within many diagnosis related group (DRG) systems, there is recognition that a single cost weight per DRG is not suitable, and that cost weights should take into account extremely lengthy hospital stays. Long lengths of stay are considered to be due to factors largely beyond the control of the hospital, and a single weight per DRG would potentially place hospitals under financial risk.

Within Canada's acute-care, inpatient grouping methodology - Case Mix Groups (CMG+) - long-stay episodes represent approximately 4.5% of all discharges. Within a CMG (analogous to DRG), the cost weight assigned to long-stay cases consists of the typical …

Lot Quality Assurance Sampling (Lqas) And The Mozambique Malaria Indicator Surveys, Caitlin Biedron, Marcello Pagano, Bethany L. Hedt, Albert Kilian, Amy Ratcliffe, Samuel Mabunda, Joseph J. Valadez

Harvard University Biostatistics Working Paper Series

No abstract provided.

Control Of Electrochemical And Ferryloxy Formation Kinetics Of Cyt P450s In Polyion Films By Heme Iron Spin State And Secondary Structure, Sadagopan Krishnan, Amila Abeykoon, John B. Schenkman, James F. Rusling

UCHC Articles - Research

Voltammetry of cytochrome P450 (cyt P450) enzymes in ultrathin films with polyions was related for the first time to electronic and secondary structure. Heterogeneous electron transfer (hET) rate constants for reduction of the cyt P450s depended on heme iron spin state, with low spin cyt P450cam giving a value 40-fold larger than high spin human cyt P450 1A2, with mixed spin human P450 cyt 2E1 at an intermediate value. Asymmetric reduction–oxidation peak separations with increasing scan rates were explained by simulations featuring faster oxidation than reduction. Results are consistent with a square scheme in which oxidized and reduced forms of …

Activity-Aware Ecg-Based Patient Authentication For Remote Health Monitoring, Janani Sriram, Minho Shin, Tanzeem Choudhury, David Kotz

Dartmouth Scholarship

Mobile medical sensors promise to provide an efficient, accurate, and economic way to monitor patients' health outside the hospital. Patient authentication is a necessary security requirement in remote health monitoring scenarios. The monitoring system needs to make sure that the data is coming from the right person before any medical or financial decisions are made based on the data. Credential-based authentication methods (e.g., passwords, certificates) are not well-suited for remote healthcare as patients could hand over credentials to someone else. Furthermore, one-time authentication using credentials or trait-based biometrics (e.g., face, fingerprints, iris) do not cover the entire monitoring period and …

Activity-Aware Ecg-Based Patient Authentication For Remote Health Monitoring, Janani Sriram, Minho Shin, Tanzeem Choudhury, David Kotz

Dartmouth Scholarship

Mobile medical sensors promise to provide an efficient, accurate, and economic way to monitor patients' health outside the hospital. Patient authentication is a necessary security requirement in remote health monitoring scenarios. The monitoring system needs to make sure that the data is coming from the right person before any medical or financial decisions are made based on the data. Credential-based authentication methods (e.g., passwords, certificates) are not well-suited for remote healthcare as patients could hand over credentials to someone else. Furthermore, one-time authentication using credentials or trait-based biometrics (e.g., face, fingerprints, iris) do not cover the entire monitoring period and …

Analysis Of Subgroup Data In Clinical Trials, Kao-Tai Tsai, Karl E. Peace

Biostatistics Faculty Presentations

This conference abstract was published in the Proceedings of the Sixteenth Annual Biopharmaceutical Applied Statistics Symposium.

Agenda: World Energy Justice Conference And Appropriate Technology Arcade, University Of Colorado Boulder. Center For Energy & Environmental Security, University Of Colorado Boulder. School Of Law

World Energy Justice Conference (October 23-24)

The 2009 CEES Energy Justice Conference took place at the University of Colorado Law School on October 23rd and 24th, 2009. It featured 11 sessions, more than 40 speakers, and attracted over 200 attendees. The Conference brought together leading international and U.S. decision-makers in politics, engineering, public health, law, business, economics, and innovators in the sciences to explore how best to address the critical needs of the energy-oppressed poor (EOP) through long-term interdisciplinary action, information sharing, and deployment of appropriate sustainable energy technologies (ASETs).

The Colorado Journal of International Environmental Law & Policy (CJIELP) at the University of Colorado Law …

Causal Inference In Epidemiological Studies With Strong Confounding, Kelly L. Moore, Romain S. Neugebauer, Mark J. Van Der Laan, Ira B. Tager

U.C. Berkeley Division of Biostatistics Working Paper Series

One of the identifiabilty assumptions of causal effects defined by marginal structural model (MSM) parameters is the experimental treatment assignment (ETA) assumption. Practical violations of this assumption frequently occur in data analysis, when certain exposures are rarely observed within some strata of the population. The inverse probability of treatment weighted (IPTW) estimator is particularly sensitive to violations of this assumption, however, we demonstrate that this is a problem for all estimators of causal effects. This is due to the fact that the ETA assumption is about information (or lack thereof) in the data. A new class of causal models, causal …

Unlv Magazine, Matthew K. Jacobsen, Holly Ivy De Vore, Lisa Arth, Cate Weeks, Greg Lacour, Tony Allen, Afsha Bawany, Barbara Cloud, Gian Galassi, Phil Hagen, Karyn S. Hollingsworth, Michelle Mouton, Erin O'Donnell

UNLV Magazine

No abstract provided.

Proteomic And Phospho-Proteomic Profile Of Human Platelets In Basal, Resting State: Insights Into Integrin Signaling, Amir H. Qureshi, Vineet Chaoji, Dony Maiguel, Mohd Hafeez Faridi, Constantinos J. Barth, Saeed M. Salem, Mudita Singhal, Darren Stoub, Bryan Krastins, Mitsunori Ogihara, Mohammed J. Zaki, Vineet Gupta

Faculty Work Comprehensive List

During atherogenesis and vascular inflammation quiescent platelets are activated to increase the surface expression and ligand affinity of the integrin αIIbβ3 via inside-out signaling. Diverse signals such as thrombin, ADP and epinephrine transduce signals through their respective GPCRs to activate protein kinases that ultimately lead to the phosphorylation of the cytoplasmic tail of the integrin αIIbβ3 and augment its function. The signaling pathways that transmit signals from the GPCR to the cytosolic domain of the integrin are not well defined. In an effort to better understand these pathways, we employed a combination of proteomic profiling and computational analyses of isolated …

Causal Inference For Nested Case-Control Studies Using Targeted Maximum Likelihood Estimation, Sherri Rose, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

A nested case-control study is conducted within a well-defined cohort arising out of a population of interest. This design is often used in epidemiology to reduce the costs associated with collecting data on the full cohort; however, the case control sample within the cohort is a biased sample. Methods for analyzing case-control studies have largely focused on logistic regression models that provide conditional and not marginal causal estimates of the odds ratio. We previously developed a Case-Control Weighted Targeted Maximum Likelihood Estimation (TMLE) procedure for case-control study designs, which relies on the prevalence probability q0. We propose the use of …

Ethical Issues In Graduate Research, William J. Frey

Ethics in Science and Engineering National Clearinghouse

(Caution! This module is being published in an incomplete, preliminary version. Later edited and fuller versions will follow.) "Graduate Education in Research Ethics for Scientists and Engineers" is a project funded by the National Science Foundation (SES 0629377) to design a pilot program in research ethics for graduate students in science and engineering. This project is built around three workshops: (1) a Graduate Awareness Workshop introduces students to fundamental ethical issues in research, (2) a Moral Deliberation Workshop acquaints students with the skills of moral deliberation, (3) a Case Analysis Workshop uses realistic scenarios to allow students to practice decision-making …

Progress Toward The Synthesis Of A Truncated Ergoline, Ryan D. Enck, Matthew Hart

Student Summer Scholars Manuscripts

Many people are diagnosed with thyroid related disorders, and many more are unaware of their existing thyroid problems. T1AM, a naturally occurring metabolite of the thyroid hormone (TH), has been shown to activate the Trace Amine Associated Receptor 1 (TAAR1) and exhibits effects that oppose those of the TH. It is, therefore, likely that there is regulatory relationship between T1AM and the TH. In order to better understand this relationship, a compound must be developed that will effectively block TAAR1. Previously our lab has examined the two different mirror images of apomorphine. One of the mirror images inhibited and the …

Professional Ethics-Responsible Conduct Of Research Training: Making Sense Of Complex Problems, Michael D. Mumford, Shane Connelly, Ryan P. Brown, Lynn D. Devenport, Stephen T. Murphy, Alison L. Antes

Ethics in Science and Engineering National Clearinghouse

General Course Abstract

This two-day seminar format course exposes students to the complexities involved in real-world ethical decision-making. It provides students with strategies, or tools, for understanding and thinking through ethical problems to arrive at a decision. Students practice working with these strategies by applying them to realistic, complex cases.

Day 1 Abstract

During the first day of the course, guidelines and principles for ethical research practices are discussed. It is emphasized that students must apply guidelines in a context to arrive at a decision, and the course provides guidance on this decision-making process. Next, students learn about the personal …

Comparing Risk Scoring Systems Beyond The Roc Paradigm In Survival Analysis, Hajime Uno, Lu Tian, Tianxi Cai, Isaac S. Kohane, L. J. Wei

Harvard University Biostatistics Working Paper Series

No abstract provided.

Operations Research Methods For Optimization In Radiation Oncology, M Ehrgott, Allen Holder

Mathematical Sciences Technical Reports (MSTR)

Operations Research has a successful tradition of applying mathematical analysis to a wide range of applications, with one of the burgeoning areas of growth being in medical physics. The original application was in the optimal design of the influence map for a radiotherapy treatment, a problem that has continued to receive attention. However, operations research has been applied to other clinical problems like patient scheduling, vault design, and image alignment. The overriding theme of this article is to present how techniques in operations research apply to clinical problems, which we accomplish in three parts. First, we present the perspective from …

Online Piece-Wise Linear Approximation Of Numerical Streams With Precision Guarantees, Hazem Elmeleegy, Ahmed Elmagarmid, Emmanuel Cecchet, Walid G. Aref, Willy Zwaenepoel

Cyber Center Publications

Continuous “always-on” monitoring is beneficial for a number of applications, but potentially imposes a high load in terms of communication, storage and power consumption when a large number of variables need to be monitored. We introduce two new filtering techniques, swing filters and slide filters, that represent within a prescribed precision a time-varying numerical signal by a piecewise linear function, consisting of connected line segments for swing filters and (mostly) disconnected line segments for slide filters. We demonstrate the effectiveness of swing and slide filters in terms of their compression power by applying them to a reallife data set plus …

Federal Register: National Science Foundation, Responsible Conduct Of Research, National Science Foundation

Ethics in Science and Engineering National Clearinghouse

The National Science Foundation (NSF) is announcing its implementation of Section 7009 of the America Creating Opportunities to Meaningfully Promote Excellence in Technology, Education, and Science (COMPETES) Act (42 U.S.C. 1862o–1). This section of the Act requires that ‘‘each institution that applies for financial assistance from the Foundation for science and engineering research or education describe in its grant proposal a plan to provide appropriate training and oversight in the responsible and ethical conduct of research to undergraduate students, graduate students, and postdoctoral researchers participating in the proposed research project.’’

[Abstract by author]

Effects Of Non-Equilibrium Plasma On Eukaryotic Cells (Final Report: Grant Fa9550-06-1-0004), Mounir Laroussi, Fred C. Dobbs, Old Dominion University

Electrical & Computer Engineering Faculty Publications

This document is our final report describing the research activities carried out under AFOSR Grant FA9550-06-1-0004. First, descriptions of our cold plasma generation systems are presented. Two systems, developed with past and present AFOSR support, are available in our laboratory. The first is a pulsed device capable of emitting a cold plasma plume in room air. The second is an air plasma generator the core of which is a dielectric barrier discharge excited by a high AC voltage. Following these brief descriptions we first present the effects of an atmospheric pressure air plasma on four different types of eukaryotic microalgae. …

Diversity And Strain Specificity Of Plant Cell Wall Degrading Enzymes Revealed By The Draft Genome Of Ruminococcus Flavefaciens Fd-1, Margret E. Berg Miller, Dionysios A. Antonopoulos, Mark Brand, Albert Bari, Alvaro Hernandez, Jyothi Thimmapuram, Bryan A. White, Marco Rincon, Harry J. Flint, Bernard Henrissat, Pedro M. Coutinho

Cyber Center Publications

Ruminococcus flavefaciens is a predominant cellulolytic rumen bacterium, which forms a multi-enzyme cellulosome complex that could play an integral role in the ability of this bacterium to degrade plant cell wall polysaccharides. Identifying the major enzyme types involved in plant cell wall degradation is essential for gaining a better understanding of the cellulolytic capabilities of this organism as well as highlighting potential enzymes for application in improvement of livestock nutrition and for conversion of cellulosic biomass to liquid fuels.

A Clustering Approach For Optimizing Beam Angles In Imrt Planning, Gino J. Lim, Allen Holder, Josh Reese

Mathematical Sciences Technical Reports (MSTR)

In this paper we introduce a p-median problem based clustering heuristic for selecting efficient beam angles for intensity-modulated radiation therapy. The essence of the method described here is the clustering of beam angles according to probability that an angle will be observed in the final solution and similarities among different angles and the selection of a representative angle from each of the p resulting cluster cells. We conduct experiments using several combinations of modeling parameters to find the conditions where the heuristic best performs. We found a combination of such parameters that outperformed all other parameters on three of the …

Complex Adaptive Systems As A Model For Evaluating Organisational Change Caused By The Introduction Of Health Information Systems, Kieren Diment Mr, Ping Yu, K. Garrety

Faculty of Informatics - Papers (Archive)

This paper documents the preliminary development of a framework for evaluating organisational change processes during the implementation of an electronic nursing documentation system in residential aged care facilities. It starts with a brief outline of organisational change processes. This is followed by a more detailed exposition of the principles underlying complex adaptive systems (CAS) theory, where we explain how mathematical concepts can be used to illuminate qualitative research approaches. Finally we present some preliminary findings on the facilitators and barriers for the introduction of the electronic documentation system, explained with reference to the CAS theory, based on analysis of interviews …

Spiroadamantyl 1,2,4-Trioxolane, 1,2,4-Trioxane, And 1,2,4-Trioxepane Pairs: Relationship Between Peroxide Bond Iron(Ii) Reactivity, Heme Alkylation Efficiency, And Antimalarial Activity, Xiaofang Wang, Darren J. Creek, Yuxiang Dong, Jacques Chollet, Christian Scheurer, Sergio Wittlin, Susan A. Charman, Patrick H. Dussault, James K. Wood, Jonathan L. Vennerstrom

Chemistry Faculty Publications

These data suggest that iron(II) reactivity for a set of homologous spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane peroxide heterocycles is a necessary, but insufficient, property of animalarial peroxides. Heme alkylation efficiency appears to give a more accurate prediction of antimalarial activity than FeSO4-mediated reaction rates, suggesting that antimalarial activity is not merely dependent on peroxide bond cleavage, but also on the ability of reactive intermediates to alkylate heme or other proximal targets.