Physical Sciences and Mathematics Commons^™

The Compensation For Few Clusters In Clustered Randomized Trials With Binary Outcomes, Lily Stalter

Mathematics & Statistics ETDs

Cluster randomized trials are increasingly popular in epidemiological and medical research. When analyzing the data from such studies it is imperative that the hierarchical structure of the data be taken into account. Multilevel logistic regression is used to analyze clustered data with binary outcomes. Previous literature shows that a greater number of clusters is more important than a large number of subjects per cluster. This paper investigates if it is possible to compensate for the increased bias found for parameter estimates when the number of clusters is decreased. A simulation study was conducted where the absolute percent relative bias for …