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LSU Doctoral Dissertations

2014

Chemistry

Chemotherapy

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Ionic Liquids And Gumbos For Biomedical And Sensing Applications, Paul Kipkorir Sang Magut Jan 2014

Ionic Liquids And Gumbos For Biomedical And Sensing Applications, Paul Kipkorir Sang Magut

LSU Doctoral Dissertations

This dissertation is a synopsis of advancements in the field of ionic liquids and a group of uniform materials based on organic salts (GUMBOS) in biomedical applications, especially with regard to cancer research. The toxicity of chemotherapeutic agents to normal tissues and drug resistance are a major concern in cancer treatment. In this dissertation, GUMBOS and nanoGUMBOS as well as ionic liquids and nanodroplets are explored as possible chemotherapeutic agents with minimal toxicity to normal cells. In the first part of my dissertation, exploitation of ionic liquid chemistry to modulate toxicity of rhodamine 6G is reported. Rhodamine 6G-based GUMBOS with …