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Full-Text Articles in Physical Sciences and Mathematics
A Permutation Test For Compound Symmetry With Application To Gene Expression Data, Tracy L. Morris, Mark E. Payton, Stephanie A. Santorico
A Permutation Test For Compound Symmetry With Application To Gene Expression Data, Tracy L. Morris, Mark E. Payton, Stephanie A. Santorico
Journal of Modern Applied Statistical Methods
The development and application of a permutation test for compound symmetry is described. In a simulation study the permutation test appears to be a level-α test and is robust to non-normality. However, it exhibits poor power, particularly for small samples.
A Semiparametric Regression Model For Oligonucleotide Arrays, Jianhua Hu, Guosheng Yin
A Semiparametric Regression Model For Oligonucleotide Arrays, Jianhua Hu, Guosheng Yin
Journal of Modern Applied Statistical Methods
A semiparametric model incorporating the spline smoothing technique is proposed to study oligonucleotide gene expression data. No specific parametric functional form is assumed for mismatch probe intensities, which allows much more flexibility in the fitted model. The new approach improves the model fitting, hence the estimation of expression indexes. The method is applied to a data set of 18 HuGeneFL arrays.