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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Power And Sample Size Estimation For Nonparametric Composite Endpoints: Practical Implementation Using Data Simulations, Paul M. Brown, Justin A. Ezekowitz
Power And Sample Size Estimation For Nonparametric Composite Endpoints: Practical Implementation Using Data Simulations, Paul M. Brown, Justin A. Ezekowitz
Journal of Modern Applied Statistical Methods
Composite endpoints are a popular outcome in controlled studies. However, the required sample size is not easily obtained due to the assortment of outcomes, correlations between them and the way in which the composite is constructed. Data simulations are required. A macro is developed that enables sample size and power estimation.
Outlier Impact And Accommodation On Power, Hongjing Liao, Yanju Li, Gordon P. Brooks
Outlier Impact And Accommodation On Power, Hongjing Liao, Yanju Li, Gordon P. Brooks
Journal of Modern Applied Statistical Methods
The outliers’ influence on power rates in ANOVA and Welch tests at various conditions was examined and compared with the effectiveness of nonparametric methods and Winsorizing in minimizing the impact of outliers. Results showed that, considering both power and Type I error, a nonparametric test is the safest choice to control the inflation of Type I error with a decent sample size and yield relatively high power.