Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Physical Sciences and Mathematics
Extraction Of Dna By Magnetic Ionic Liquids: Tunable Solvents For Rapid And Selective Dna Analysis, Kevin D. Clark, Omprakash Nacham, Honglian Yu, Tianhao Li, Melissa M. Yamsek, Donald R. Ronning, Jared L. Anderson
Extraction Of Dna By Magnetic Ionic Liquids: Tunable Solvents For Rapid And Selective Dna Analysis, Kevin D. Clark, Omprakash Nacham, Honglian Yu, Tianhao Li, Melissa M. Yamsek, Donald R. Ronning, Jared L. Anderson
Jared L. Anderson
DNA extraction represents a significant bottleneck in nucleic acid analysis. In this study, hydrophobic magnetic ionic liquids (MILs) were synthesized and employed as solvents for the rapid and efficient extraction of DNA from aqueous solution. The DNA-enriched microdroplets were manipulated by application of a magnetic field. The three MILs examined in this study exhibited unique DNA extraction capabilities when applied toward a variety of DNA samples and matrices. High extraction efficiencies were obtained for smaller single-stranded and double-stranded DNA using the benzyltrioctylammonium bromotrichloroferrate(III) ([(C8)3BnN+][FeCl3Br–]) MIL, while the dicationic 1,12-di(3-hexadecylbenzimidazolium)dodecane bis[(trifluoromethyl)sulfonyl]imide bromotrichloroferrate(III) ([(C16BnIM)2C122+][NTf2–, FeCl3Br–]) MIL produced higher extraction efficiencies for larger …
Abraham Model Correlations For Predicting Gas-To-Liquid Partition Coefficients And Activity Coefficients Of Organic Solutes Dissolved In 1-(2-Methoxyethyl)-1- Methylpyrrolidinium Tris(Pentafluoroethyl)Trifluorophosphate, Rui Jiang, Jared L. Anderson, Timothy W. Stephens, William E. Acree Jr., Micael H. Abraham
Abraham Model Correlations For Predicting Gas-To-Liquid Partition Coefficients And Activity Coefficients Of Organic Solutes Dissolved In 1-(2-Methoxyethyl)-1- Methylpyrrolidinium Tris(Pentafluoroethyl)Trifluorophosphate, Rui Jiang, Jared L. Anderson, Timothy W. Stephens, William E. Acree Jr., Micael H. Abraham
Jared L. Anderson
Chromatographic retention factors were measured for 45 different organic solutes of varying polarity and hydrogen-bonding capability on an anhydrous 1-(2-methoxyethyl)-1-methylpyrrolidinium tris(pentafluoroethyl)trifluorophosphate, ([MeoeMPyrr]+ [FAP]– ), stationary phase at both 323 K and 353 K. The experimental retention factor data were combined with recently published thermodynamic data for solutes dissolved in ([MeoeMPyrr]+ [FAP]– ) to give the corresponding gas-to-liquid partition coefficients (log K). The water-to-anhydrous ([MeoeMPyrr]+ [FAP]– ) partition coefficients (log P) were also calculated using published gas-to-water partition coefficient data for the solutes studied. The derived partition coefficients were analyzed in accordance with the Abraham model. The Abraham model expressions that …
Determination Of The Solubilizing Character Of 1-Methoxyethyl-1- Methylpiperidinium Tris(Pentafluoroethyl)Trifluorophosphate Based On The Abraham Solvation Parameter Model, Pamela Twu, Jared L. Anderson, Timothy W. Stephens, William E. Acree Jr., Michael H. Abraham
Determination Of The Solubilizing Character Of 1-Methoxyethyl-1- Methylpiperidinium Tris(Pentafluoroethyl)Trifluorophosphate Based On The Abraham Solvation Parameter Model, Pamela Twu, Jared L. Anderson, Timothy W. Stephens, William E. Acree Jr., Michael H. Abraham
Jared L. Anderson
Chromatographic retention data were measured for a chemically diverse set of organic solutes on an anhydrous 1-methoxyethyl-1-methylpiperidinium tris(pentafluoroethyl)trifluorophosphate, ([MeoeMPip]+ [FAP]–), stationary phase at both 323 K and 353 K. The experimental retention factors were combined with previously published thermodynamic data and gas-to-water partition coefficient data to yield gas-to-anhydrous ionic liquid (IL) and water-to-anhydrous IL partition coefficients. The three sets of partition coefficient data were analyzed in accordance with the Abraham model. The Abraham model correlations that were determined in the present study describe the observed gas-to-([MeoeMPip]+[FAP]–) (log K) and water-to-([MeoeMPip]+[FAP]–) (log P) partition coefficient data to within average standard deviations …