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Uptake And Accumulation Of Engineered Nanomaterials By Agricultural Crops And Associated Risks In The Environment And Food Safety, Yingqing Deng
Uptake And Accumulation Of Engineered Nanomaterials By Agricultural Crops And Associated Risks In The Environment And Food Safety, Yingqing Deng
Doctoral Dissertations
Engineered nanomaterials (ENMs) are being discharged into the environment and to agricultural fields, with unknown impacts on crop species. This study focused on the bioaccumulation of engineered nanomaterials into crops and the associated impact on plant growth and plant uptake of secondary contaminant. Investigations into the interactions between nanomaterials and agricultural plants will provide a more developed understanding of nanomaterials implications in the environment; in addition, evaluations of the risks associated with plant-nanomaterials interactions will provide guidelines for safe use of nanomaterials in agriculture. In the screening study on phytotoxicity, carbon-based nanoparticles (NPs) including C60, MWCNTs, NH2 …
Contribution Of New Thiol Antioxidant In The Treatment Of Acetaminophen Toxicity, Ahdab Naeem Khayyat
Contribution Of New Thiol Antioxidant In The Treatment Of Acetaminophen Toxicity, Ahdab Naeem Khayyat
Doctoral Dissertations
"Acetaminophen (N-acetyl-p-aminophenol, APAP) is one of the most widely used over-the-counter antipyretic analgesic medications. It is safe at therapeutic doses, but an overdose can result in severe hepato-nephrotoxicity, a leading cause of drug-induced acute liver failure in the U.S. Although a few different mechanisms have been proposed for APAP-induced toxicity, a significant amount of evidence has pointed to the potential involvement of oxidative stress in acetaminophen toxicity. Depletion of glutathione (GSH) is one of the initiating steps in APAP-induced toxicity; therefore, one strategy for restricting organ damage is to restore GSH levels by using GSH prodrugs like N-acetylcysteine (NAC). Although …