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Full-Text Articles in Physical Sciences and Mathematics
Synergistic Effect Of Nanoclay And Barium Sulfate Fillers On The Corrosion Resistance Of Polyester Powder Coatings, Jinbao Huang, Marshall Shuai Yang, Chengqian Xian, James Joseph Noel, Yolanda S. Hedberg, Jian Chen, Ubong Eduok, Ivan Barker, Jeffrey Daniel Henderson, Haiping Zhang, Liqin Wang, Hui Zhang, Jesse Zhu
Synergistic Effect Of Nanoclay And Barium Sulfate Fillers On The Corrosion Resistance Of Polyester Powder Coatings, Jinbao Huang, Marshall Shuai Yang, Chengqian Xian, James Joseph Noel, Yolanda S. Hedberg, Jian Chen, Ubong Eduok, Ivan Barker, Jeffrey Daniel Henderson, Haiping Zhang, Liqin Wang, Hui Zhang, Jesse Zhu
Chemistry Publications
No abstract provided.
Quantum Chemical Lipophilicities Of Antimalarial Drugs In Relation To Terminal Half-Life, Joseph D. Alia, Sheila Karl, Tyler D. Kelly
Quantum Chemical Lipophilicities Of Antimalarial Drugs In Relation To Terminal Half-Life, Joseph D. Alia, Sheila Karl, Tyler D. Kelly
Chemistry Publications
According to the WHO, artemisinin-based combination therapies (ACTs) have been integral to the recent reduction in deaths due to Plasmodium falciparum malaria. ACT-resistant strains are an emerging problem and have evolved altered developmental stages, reducing exposure of the most susceptible stages to artemisinin drugs in popular ACTs. Lipophilicity, log Kow, is a guide in understanding and predicting pharmacokinetic properties such as terminal half-life which alters drug exposure. Consistent log Kow values are not necessarily available for artemisinin derivatives designed to extend terminal half-life, increase bioavailability, and reduce neurotoxicity. For other drugs used in ACTs, an assortment of …