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Full-Text Articles in Physical Sciences and Mathematics
Using Math In Cell Biology: A Tale Of Two Channel Types, Borbala Mazzag
Using Math In Cell Biology: A Tale Of Two Channel Types, Borbala Mazzag
Borbala Mazzag
No abstract provided.
Computational Modeling Of Calcium Dynamics Near Heterogeneous Release Sites, Borbala Mazzag, Zachary Cooper, Michael Greenwood
Computational Modeling Of Calcium Dynamics Near Heterogeneous Release Sites, Borbala Mazzag, Zachary Cooper, Michael Greenwood
Borbala Mazzag
Background: Calcium is known to play an important role in many physiological
processes, such as egg fertilization and heart muscle functions.
Several recent theoretical studies ([4], [1]) investigated calcium dynamics
near so-called release sites – clusters of calcium-regulated channels on
the intracellular calcium stores. Interest in the synchronized openings of
channels within a release site has increased because these openings are
thought to be the building blocks of global calcium events.
Methods: We conduct computational studies of the effect of heterogeneity
in the make-up of the release site on the resulting calcium dynamics.
We introduce heterogeneity into the model of …