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Full-Text Articles in Physical Sciences and Mathematics

Distributed Approach For Peptide Identification, Naga V K Abhinav Vedanbhatla Oct 2015

Distributed Approach For Peptide Identification, Naga V K Abhinav Vedanbhatla

Masters Theses & Specialist Projects

A crucial step in protein identification is peptide identification. The Peptide Spectrum Match (PSM) information set is enormous. Hence, it is a time-consuming procedure to work on a single machine. PSMs are situated by a cross connection, a factual score, or a probability that the match between the trial and speculative is right and original. This procedure takes quite a while to execute. So, there is demand for enhancement of the performance to handle extensive peptide information sets. Development of appropriate distributed frameworks are expected to lessen the processing time.

The designed framework uses a peptide handling algorithm named C-Ranker, …


An Apache Hadoop Framework For Large-Scale Peptide Identification, Harinivesh Donepudi Jul 2015

An Apache Hadoop Framework For Large-Scale Peptide Identification, Harinivesh Donepudi

Masters Theses & Specialist Projects

Peptide identification is an essential step in protein identification, and Peptide Spectrum Match (PSM) data set is huge, which is a time consuming process to work on a single machine. In a typical run of the peptide identification method, PSMs are positioned by a cross correlation, a statistical score, or a likelihood that the match between the trial and hypothetical is correct and unique. This process takes a long time to execute, and there is a demand for an increase in performance to handle large peptide data sets. Development of distributed frameworks are needed to reduce the processing time, but …


Moneyware: Simulating Software Portfolio Quality Management, Robert David Beverly May 2015

Moneyware: Simulating Software Portfolio Quality Management, Robert David Beverly

Masters Theses & Specialist Projects

In this research we introduce MoneyWare, a simulator designed to explore and ultimately to provide guidance on simulating software portfolio quality management. The name “MoneyWare” is inspired by the movie Moneyball. It chronicled a baseball team which used more descriptive statistics to achieve a higher quality ball club with limited resources. MoneyWare is inspired by the observation that the problem of software development is somewhat analogous. Management is faced with an incoming stream of tasks for development. The tasks vary in terms of size, priority, risk, and date needed. But, in any case, the demands come to more than the …


Generating Random Walks And Polygons With Thickness In Confinement, Sai Sindhuja Veeramachaneni May 2015

Generating Random Walks And Polygons With Thickness In Confinement, Sai Sindhuja Veeramachaneni

Masters Theses & Specialist Projects

Algorithms to generate walks (chains of unit-length, freely-jointed segments) and polygons (closed walks) in spherical confinements have been developed in the last few years. These algorithms generate polygons inside spherical confinement based on their mathematically derived probability distributions. The generated polygons do not occupy any volume { although that would be useful for some applications. This thesis investigates how to generate walks and polygons which occupy some volume in spherical confinement. More specifically, in this thesis, existing methods described in the literature have been studied and implemented to generate walks and polygons in confinement. Additionally, these methods were adapted to …


Alcts Crs Holdings Information Forum, 3-4 P.M. January 31, 2015, Connie Foster Jan 2015

Alcts Crs Holdings Information Forum, 3-4 P.M. January 31, 2015, Connie Foster

Connie Foster

Cecilia Genereux (data management & access/metadata & intellectual access, University of Minnesota Libraries) introduced the session by confessing to a pun intended for her presentation: Alma: To Have and to Hold. The levity quickly shifted into some very detailed analysis of the way the Ex Libris Alma system handled specific types of serials during a migration from Aleph. The University of Minnesota started with Aleph (Ex Libris) in 2002 and moved to Alma on December 26, 2013. Frances McNamara (director, Integrated Library Systems and Administrative and Desktop Systems at University of Chicago), discussed migrating serials data from Horizon to Kulai …