Physical Sciences and Mathematics Commons^™

Oscillations In Neuronal Activity: A Neuron-Centered Spatiotemporal Model Of The Unfolded Protein Response In Prion Diseases, Elliot M. Miller, Tat Chung D. Chan, Carlos Montes-Matamoros, Omar Sharif, Laurent Pujo-Menjouet, Michael R. Lindstrom

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Many neurodegenerative diseases (NDs) are characterized by the slow spatial spread of toxic protein species in the brain. The toxic proteins can induce neuronal stress, triggering the Unfolded Protein Response (UPR), which slows or stops protein translation and can indirectly reduce the toxic load. However, the UPR may also trigger processes leading to apoptotic cell death and the UPR is implicated in the progression of several NDs. In this paper, we develop a novel mathematical model to describe the spatiotemporal dynamics of the UPR mechanism for prion diseases. Our model is centered around a single neuron, with representative proteins P …

Using Bayesian Multispecies Models To Evaluate Fish And Invertebrate Detection Probability And Distribution In The Hypersaline Bahia Grande Tidal Basin, Roy M. Ulibarri, Catherine M. Eckert, David Hicks, David Montagne, Brandon Jones, David R. Stewart

School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations

Objective

In 2000, the Laguna Atascosa National Wildlife Refuge acquired the Bahia Grande (Texas) management unit, a space that had lain barren and arid for 70 years. A large cooperative partnership launched a restoration project to replenish the basin and recover its original tidal hydrology. In 2005, the construction of a pilot channel successfully restored water throughout the basin, and plans to eventually widen the channel were developed. Our study aims to evaluate an estuarine habitat restoration by assessing ecological drivers and the impacts on species diversity.

Methods

We evaluated species richness, detection/occupancy rates, and species–habitat relationships, and we estimated …

A Novel Consumer-Centric Metric For Evaluating Hearing Device Audio Performance, Vinaya Manchaiah, Steve Taddei, Abram Bailey, De Wet Swanepoel, Hansapani Rodrigo

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Background and Aim: The emergence of direct-to-consumer hearing devices has introduced confusion in making appropriate choices, highlighting the need for users to be well-informed for optimal device selection. Currently, no established metric offers insights into the sound performance of these devices. This study aimed to introduce and assess a novel consumer-centric metric (i.e., SoundScore) for hearing device audio performance.

Method: The SoundScore metric was created based on five dimensions of hearing device audio performance (i.e., speech benefit in quiet and moderate, speech benefit in loud, own voice perception, feedback control, streamed music sound quality). Tests were conducted under lab conditions …

Biotechnology For Sustainable Materials: Innovating Today For A Greener Tomorrow, Shashi Kant Bhatia, Saurabh Bhatia, Maria Eugenia Inda-Webb, Konstantina Kourmentza, Tae Seok Moon, Vijai Singh, Vishal Ahuja, Jingbo Li, Sanjeet Mehariya, Jikai Zhao

School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations

No abstract provided.

Peace With Painful Memories, Mona Muzammil, Muzammil Arshad, Washain Muzammil

Chemistry Faculty Publications and Presentations

This Book helps you identify and heal from childhood emotional neglect so you can be more connected and emotionally present in your life.

Do you sometimes feel like you’re just going through the motions in life? Do you often act like you’re fine when you secretly feel lonely and disconnected? Perhaps you have a good life and yet somehow, it’s not enough to make you happy. Or perhaps you drink too much, eat too much, or risk too much to feel something good. If so, you are not alone and you may be suffering from emotional neglect.

Are you one …

Weighted Ehrhart Theory: Extending Stanley's Nonnegativity Theorem, Esme Bajo, Robert Davis, Jesús A. De Loera, Alexey Garber, Sofía Garzón Mora, Katharina Jochemko, Josephine Yu

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

We generalize R. P. Stanley's celebrated theorem that the h∗-polynomial of the Ehrhart series of a rational polytope has nonnegative coefficients and is monotone under containment of polytopes. We show that these results continue to hold for weighted Ehrhart series where lattice points are counted with polynomial weights, as long as the weights are homogeneous polynomials decomposable as sums of products of linear forms that are nonnegative on the polytope. We also show nonnegativity of the h∗-polynomial as a real-valued function for a larger family of weights.

We generalize R. P. Stanley's celebrated theorem that the h ⁎ -polynomial of …

Ramanujan Type Congruences For Quotients Of Klein Forms, Timothy Huber, Nathaniel Mayes, Jeffery Opoku, Dongxi Ye

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

In this work, Ramanujan type congruences modulo powers of primes p≥5 are derived for a general class of products that are modular forms of level p. These products are constructed in terms of Klein forms and subsume generating functions for t-core partitions known to satisfy Ramanujan type congruences for p=5,7,11. The vectors of exponents corresponding to products that are modular forms for Γ1(p) are subsets of bounded polytopes with explicit parameterizations. This allows for the derivation of a complete list of products that are modular forms for Γ1(p) of weights 1≤k≤5 for primes 5≤p≤19 and whose Fourier coefficients …

Local Existence Of Solutions To A Nonlinear Autonomous Pde Model For Population Dynamics With Nonlocal Transport And Competition, Michael R. Lindstrom

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Highlights

• Partial differential equation models are ubiquitous in applied sciences.

• A partial differential equation based in ecology is studied for solution existence.

• Energy methods and convergence analysis lead to local classical solutions.

Abstract

In this paper, we prove that a particular nondegenerate, nonlinear, autonomous parabolic partial differential equation with nonlocal mass transfer admits the local existence of classical solutions. The equation was developed to qualitatively describe temporal changes in population densities over space through accounting for location desirability and fast, long-range travel. Beginning with sufficiently regular initial conditions, through smoothing the PDE and employing energy arguments, we obtain a sequence …

Year-Round Co2 Emissions From The Drawdown Area Of A Tropical Reservoir: Strong Seasonal And Spatial Variation, Ícaro Barbosa, José R. Paranaíba, Sebastian Sobek, Sarian Kosten, Rafael M. Almeida, Vitor Duque, Natália Mendonça, Nathan Barros, Raquel Mendonça

School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations

Highlights

• Drawdown areas emitted 80% of reservoir CO2 with just 1/5 area.

• Emissions from reservoir shorelines near forests were greater than from areas near grassland.

• CO2 emissions increase with the distance from the water.

• Estimates of reservoir drawdown CO2 flux vary by ∼ 300 % across the seasons examined here.

• There was no discernible difference in CO2 emissions between day and night-time.

• A significant increase in CO2 fluxes was observed 30 min after a rewetting event.

Abstract

A growing body of literature points to drawdown areas as important sources of atmospheric CO2 within reservoirs. Yet seasonal and temporal patterns of …

Skimming Genomes For Systematics And Dna Barcodes Of Corals, Andrea M. Quattrini, Luke J. Mccartin, Erin E. Easton, Jeremy Horowitz, Herman H. Wirshing, Hailey Bowers, Kenneth Mitchell, María Del P. González-García, Makiri Sei, Catherine S. Mcfadden

School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations

Numerous genomic methods developed over the past two decades have enabled the discovery and extraction of orthologous loci to help resolve phylogenetic relationships across various taxa and scales. Genome skimming (or low-coverage genome sequencing) is a promising method to not only extract high-copy loci but also 100s to 1000s of phylogenetically informative nuclear loci (e.g., ultraconserved elements [UCEs] and exons) from contemporary and museum samples. The subphylum Anthozoa, including important ecosystem engineers (e.g., stony corals, black corals, anemones, and octocorals) in the marine environment, is in critical need of phylogenetic resolution and thus might benefit from a genome-skimming approach. We …

Remnant Polarization And Structural Arrangement In P(Vdf-Trfe) Electrospun Fiber Meshes Affect Osteogenic Differentiation Of Human Mesenchymal Stromal Cells, Bahareh Azimi, Massimiliano Labardi, Mohammad Sajad Sorayani Bafqi, Teresa Macchi, Claudio Ricci, Veronica Carnicelli, Lorenzo Scarpelli, Istiak Hussain, Francesca Matino, Mohammed Uddin

Physics and Astronomy Faculty Publications and Presentations

Highlights

• The type of solvent had noticeable effects on morphology and piezoelectric properties of P(VDF-TrFE) electrospun fibers.

• Using MEK as a solvent and specific environmental conditions led to the obtainment of surface nanopores.

• Uniaxially aligned fibers exhibited higher β phase and mechanical properties than random ones.

• Randomly oriented fibers had higher remnant piezoelectric properties (Vout, d31 piezoelectric coefficient) than aligned ones.

• Human mesenchymal stem cells cultured on randomly oriented fibers showed an accelerated osteogenic differentiation.

Abstract

Many tissues and cells are influenced by mechano-electric stimulation, thus the application of piezoelectric materials has recently received considerable attention in tissue engineering. …

Statistics For Iwasawa Invariants Of Elliptic Curves, Ii, Debanjana Kundu, Anwesh Ray

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

We study the average behavior of the Iwasawa invariants for Selmer groups of elliptic curves. These results lie at the intersection of arithmetic statistics and Iwasawa theory. We obtain lower bounds for the density of rational elliptic curves with prescribed Iwasawa invariants.

A Search For Intermediate-Mass Black Holes In Compact Stellar Systems Through Optical Emissions From Tidal Disruption Events, Richard T. Pomeroy, Mark A. Norris

Physics and Astronomy Faculty Publications and Presentations

Intermediate-mass black holes (IMBH) are expected to exist in globular clusters (GCs) and compact stellar systems (CSS) in general, but none have been conclusively detected. Tidal disruption events (TDEs), where a star is tidally disrupted by the gravitational field of a black hole, have been observed to occur around the supermassive black holes (SMBH) found at the centres of galaxies, and should also arise around IMBHs, especially in the dense stellar cores of CSS's. However, to date none have been observed in such environments. Using data from the Zwicky Transient Facility (ZTF) we search for TDEs associated with CSS, but …

Search For Extreme Mass Ratio Inspirals Using Particle Swarm Optimization And Reduced Dimensionality Likelihoods, Xiao-Bo Zou, Soumya Mohanty, Hong-Gang Luo, Yu-Xiao Liu

Physics and Astronomy Faculty Publications and Presentations

Extreme-mass-ratio inspirals (EMRIs) are significant observational targets for spaceborne gravitational wave detectors, namely, LISA, Taiji, and Tianqin, which involve the inspiral of stellar-mass compact objects into massive black holes (MBHs) with a mass range of approximately 104 ∼107𝑀⊙ . EMRIs are estimated to produce long-lived gravitational wave signals with more than 105 cycles before plunge, making them an ideal laboratory for exploring the strong-gravity properties of the spacetimes around the MBHs, stellar dynamics in galactic nuclei, and properties of the MBHs itself. However, the complexity of the waveform model, which involves the superposition of multiple harmonics, as well as the …

Study Of Hybrid Nanofluid Flow In A Stationary Cone-Disk System With Temperature-Dependent Fluid Properties, A. S. John, Mahanthesh Basavarajappa, G. Lorenzini

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Cone-disk systems find frequent use such as conical diffusers, medical devices, various rheometric, and viscosimetry applications. In this study, we investigate the three-dimensional flow of a water-based Ag-MgO hybrid nanofluid in a static cone-disk system while considering temperature-dependent fluid properties. How the variable fluid properties affect the dynamics and heat transfer features is studied by Reynolds’s linearized model for variable viscosity and Chiam’s model for variable thermal conductivity. The single-phase nanofluid model is utilized to describe convective heat transfer in hybrid nanofluids, incorporating the experimental data. This model is developed as a coupled system of convective-diffusion equations, encompassing the conservation …

Normalized Ground State Of A Mixed Dispersion Nonlinear Schrodinger Equation With Combined Power-Type Nonlinearities, Zhouji Ma, Xiaojun Chang, Zhaosheng Feng

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

We study the existence of normalized ground state solutions to a mixed dispersion fourth-order nonlinear Schrodinger equation with combined power-type nonlinearities. By analyzing the subadditivity of the ground state energy with respect to the prescribed mass, we employ a constrained minimization method to establish the existence of ground state that corresponds to a local minimum of the associated functional. Under certain conditions, by studying the monotonicity of ground state energy as the mass varies, we apply the constrained minimization arguments on the Nehari-Pohozaev manifold to prove the existence of normalized ground state solutions.

Methionine Sulfoxide Speciation In Mouse Hippocampus Revealed By Global Proteomics Exhibits Age And Alzheimer’S Disease Dependent Changes Targeted To Mitochondrial And Glycolytic Pathways, Fillipa Blasco Tavares Pereira Lopes, Daniela Schlatzer, Mengzhen Li, Serhan Yılmaz, Rihua Wang, Xin Qi, Marzieh Ayati, Mehmet Koyutürk, Mark R. Chance

Computer Science Faculty Publications and Presentations

Methionine oxidation to the sulfoxide form (MSox) is a poorly understood post-translational modification of proteins associated with nonspecific chemical oxidation from reactive oxygen species (ROS) whose chemistries are linked to various disease pathologies including neurodegeneration. Emerging evidence shows MSox site occupancy is in some cases under enzymatic regulatory control mediating cellular signaling including phosphorylation and/or calcium signaling, raising questions as to the speciation and functional nature of MSox across the proteome. The 5XFAD lineage of the C57BL/6 mouse has well-defined Alzheimer’s and aging states. Using this model, we analyzed age, sex and disease dependent MSox speciation in mouse hippocampus. In …

Reevaluating The Origin Of Detectable Cataclysmic Variables In Globular Clusters: Testing The Importance Of Dynamics, Liliana Rivera Sandoval, Diogo Belloni, Miriam Ramos Arevalo

Physics and Astronomy Faculty Publications and Presentations

Based on the current detectable cataclysmic variable (CV) population in Galactic globular clusters (GCs), we show that there is not a clear relation between the number of sources per unit of mass and the stellar encounter rate, the cluster mass, or the cluster central density. If any, only in the case of core-collapsed GCs could there be an anticorrelation with the stellar encounter rate. Our findings contrast with previous studies where clear positive correlations were identified. Our results suggest that correlations between faint X-ray sources, from which often conclusions for the CV population are drawn, and the GC parameters considered …

A Joint Fermi-Gbm And Swift-Bat Analysis Of Gravitational-Wave Candidates From The Third Gravitational-Wave Observing Run, C. Fletcher, J. Wood, R. Hamburg, Michael G. Benjamin, Teviet Creighton, Mario C. Diaz, Francisco Llamas, Soma Mukherjee, Gaukhar Nurbek, Volker Quetschke, Wenhui Wang

Physics and Astronomy Faculty Publications and Presentations

We present Fermi Gamma-ray Burst Monitor (Fermi-GBM) and Swift Burst Alert Telescope (Swift-BAT) searches for gamma-ray/X-ray counterparts to gravitational-wave (GW) candidate events identified during the third observing run of the Advanced LIGO and Advanced Virgo detectors. Using Fermi-GBM onboard triggers and subthreshold gamma-ray burst (GRB) candidates found in the Fermi-GBM ground analyses, the Targeted Search and the Untargeted Search, we investigate whether there are any coincident GRBs associated with the GWs. We also search the Swift-BAT rate data around the GW times to determine whether a GRB counterpart is present. No counterparts are found. Using both the Fermi-GBM Targeted Search …

The Invariantring Package For Macaulay2, Luigi Ferraro, Federico Galetto, Francesca Gandini, Hang Huang, Matthew Mastroeni, Xianglong Ni

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

We describe a significant update to the existing InvariantRing package for Macaulay2. In addition to expanding and improving the methods of the existing package for actions of finite groups, the updated package adds functionality for computing invariants of diagonal actions of tori and finite abelian groups, as well as invariants of arbitrary linearly reductive group actions. The implementation of the package has been completely overhauled with the aim of serving as a unified resource for invariant theory computations in Macaulay2.

Ex-Vivo Hippocampus Segmentation Using Diffusion-Weighted Mri, Haoteng Tang, Siyuan Dai, Eric M. Zou, Guodong Liu, Ryan Ahearn, Ryan Krafty, Michel Modo, Liang Zhan

Computer Science Faculty Publications and Presentations

The hippocampus is a crucial brain structure involved in memory formation, spatial navigation, emotional regulation, and learning. An accurate MRI image segmentation of the human hippocampus plays an important role in multiple neuro-imaging research and clinical practice, such as diagnosing neurological diseases and guiding surgical interventions. While most hippocampus segmentation studies focus on using T1-weighted or T2-weighted MRI scans, we explore the use of diffusion-weighted MRI (dMRI), which offers unique insights into the microstructural properties of the hippocampus. Particularly, we utilize various anisotropy measures derived from diffusion MRI (dMRI), including fractional anisotropy, mean diffusivity, axial diffusivity, and radial diffusivity, for …

Algebraic Structures On Parallelizable Manifolds, Sergey Grigorian

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

In this paper we explore algebraic and geometric structures that arise on parallelizable manifolds. Given a parallelizable manifold L, there exists a global trivialization of the tangent bundle, which defines a map ρp : l −→ TpL for each point p ∈ L, where l is some vector space. This allows us to define a particular class of vector fields, known as fundamental vector fields, that correspond to each element of l. Furthermore, flows of these vector fields give rise to a product between elements of l and L, which in turn induces a local loop structure (i.e. a non-associative …

Adsorption Of Crystal Violet Dye From Synthetic Wastewater By Ball-Milled Royal Palm Leaf Sheath, Neloy Sen, Nawrin Rahman Shefa, Kismot Reza, Sk Md Ali Zaker Shawon, Md. Wasikur Rahman

Physics and Astronomy Faculty Publications and Presentations

The current study shows that using a batch approach to remove crystal violet dye from synthetic wastewater is feasible when using royal palm leaf sheath powder as an adsorbent. In order to investigate the effects of many parameters, including starting concentration, pH effect, dye concentration, adsorbent dose, contact time, and temperature, experiments were carried out under various operating conditions. Maximum removal was obtained at pH 6 and at a concentration of 100 ppm, which are considered as ideal values. The influence of pH and dye concentration was shown to be substantial. Langmuir, Freundlich, and Temkin isotherm models were fitted to …

Numerical Simulations For Fractional Differential Equations Of Higher Order And A Wright-Type Transformation, Mariana Nacianceno, Tamer Oraby, Hansapani Rodrigo, Y. Sepulveda, Josef A. Sifuentes, Erwin Suazo, T. Stuck, J. Williams

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

In this work, a new relationship is established between the solutions of higher fractional differential equations and a Wright-type transformation. Solutions could be interpreted as expected values of functions in a random time process. As applications, we solve the fractional beam equation, fractional electric circuits with special functions as external sources, and derive d’Alembert’s formula for the fractional wave equation. Due to this relationship, we present two methods for simulating solutions of fractional differential equations. The two approaches use the interpretation of the Caputo derivative of a function as a Wright-type transformation of the higher derivative of the function. In …

Possible Role Of Correlation Coefficients And Network Analysis Of Multiple Intracellular Proteins In Blood Cells Of Patients With Bipolar Disorder In Studying The Mechanism Of Lithium Responsiveness: A Proof-Concept Study, Keming Gao, Marzieh Ayati, Nicholas M. Kaye, Mehmet Koyutürk, Joseph R. Calabrese, Eric Christian, Hillard M. Lazarus, David Kaplan

Computer Science Faculty Publications and Presentations

Background: The mechanism of lithium treatment responsiveness in bipolar disorder (BD) remains unclear. The aim of this study was to explore the utility of correlation coefficients and protein-to-protein interaction (PPI) network analyses of intracellular proteins in monocytes and CD4+ lymphocytes of patients with BD in studying the potential mechanism of lithium treatment responsiveness. Methods: Patients with bipolar I or II disorder who were diagnosed with the MINI for DSM-5 and at any phase of the illness with at least mild symptom severity and received lithium (serum level ≥ 0.6 mEq/L) for 16 weeks were divided into two groups, responders (≥50% …

Powerful Radio Sources In The Southern Sky. Iii. First Results Of The Optical Spectroscopic Campaign, A. García-Pérez, H. A. Peña-Herazo, A. Jimenez-Gallardo, V. Chavushyan, F. Massaro, S. V. White, A. Capetti, B. Balmaverde, W. R. Forman, Juan P. Madrid

Physics and Astronomy Faculty Publications and Presentations

We recently built the G4Jy-3CRE catalog of extragalactic radio sources. This catalog lists 264 powerful radio sources selected with similar criteria to those of the revised Third Cambridge Catalog, but visible from the Southern Hemisphere. A literature search revealed that 119 sources in the G4Jy-3CRE catalog (i.e., 45%) lack a firm spectroscopic redshift measurement. Here, we present a campaign aimed at acquiring optical spectra of G4Jy-3CRE sources and measuring their redshifts. We used single-slit observations obtained with the Víctor Blanco Telescope, the New Technology Telescope, the Southern Astrophysical Research Telescope, and the 2.1 m telescope of the Observatorio Astronómico Nacional …

Comment On “Spectral Shifts In General Relativity,” [Am. J. Phys. 62(10), 903–907 (1994)], Joseph D. Romano, Teviet Creighton

Physics and Astronomy Faculty Publications and Presentations

No abstract provided.

Strongly Magnetized Accretion In Two Ultracompact Binary Systems, Thomas J. Maccarone, Thomas Kupfer, Edgar Najera Casarrubias, Liliana E. Rivera Sandoval, Aarran W. Shaw, Christoper T. Britt, Jan Van Roestel, David R. Zurek

Physics and Astronomy Faculty Publications and Presentations

We present the discoveries of two of AM CVn systems, Gaia14aae and SDSS J080449.49+161624.8, which show X-ray pulsations at their orbital periods, indicative of magnetically collimated accretion. Both also show indications of higher rates of mass transfer relative to the expectations from binary evolution driven purely by gravitational radiation, based on existing optical data for Gaia14aae, which show a hotter white dwarf temperature than expected from standard evolutionary models, and X-ray data for SDSS J080449.49+161624.8 which show a luminosity 10−100 times higher than those for other AM CVn at similar orbital periods. The higher mass transfer rates could be driven …

Extrasynaptic Localization Is Essential For Α5gabaa Receptor Modulation Of Dopamine System Function, Alexandra M. Mccoy, Thomas D. Prevot, Md Yeunus Mian, Dishary Sharmin, Adeeba N. Ahmad, James M. Cook, Etienne L. Sibille, Daniel J. Lodge

Chemistry Faculty Publications and Presentations

Dopamine system dysfunction, observed in animal models with psychosis-like symptomatology, can be restored by targeting gamma-aminobutyric acid type A receptors (GABAARs) containing the α5, but not α1, subunit in the ventral hippocampus (vHipp). The reason for this discrepancy in efficacy remains elusive; however, one key difference is that gamma-aminobutyric acid type A receptors containing the α1 subunit (α1GABAARs) are primarily located in the synapse, whereas gamma-aminobutyric acid type A receptors containing the α5 subunit (α5GABAARs) are mostly extrasynaptic. To test whether receptor location is responsible for this difference in efficacy, we injected an siRNA into the vHipp to knock down …

Finite Element Solution Of Crack-Tip Fields For An Elastic Porous Solid With Density-Dependent Material Moduli And Preferential Stiffness, Hyun C. Yoon, S. M. Mallikarjunaiah, Dambaru Bhatta

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

In this paper, the finite element solutions of crack-tip fields for an elastic porous solid with density-dependent material moduli are presented. Unlike the classical linearized case in which material parameters are globally constant under a small strain regime, the stiffness of the model presented in this paper can depend upon the density with a modeling parameter. The proposed constitutive relationship appears linear in the Cauchy stress and linearized strain independently. From a subclass of the implicit constitutive relation, the governing equation is bestowed via the balance of linear momentum, resulting in a quasi-linear partial differential equation (PDE) system. Using the …