Physical Sciences and Mathematics Commons^™

Measuring Polarized Emission In Clusters In The Cmb S4 Era, Louis Thibaut, Emory F. Bunn, Benjamin Wandelt, Joseph Silk

Physics Faculty Publications

The next generation of CMB experiments (CMB Stage-4) will produce a Sunyaev-Zel’dovich (SZ) cluster catalog containing ∼105 objects, two orders of magnitudes more than currently available. In this paper, we discuss the detectability of the polarized signal generated by scattering of the CMB quadrupole on the cluster electron gas using this catalog. We discuss the possibility of using this signal to measure the relationship between cluster optical depth and mass. We find that the area of observation of S4 maximizes the signal-to-noise (S/N) on the polarized signal but that this S/N is extremely small for an individual cluster, of order …

A Tidy Data Model For Natural Language Processing Using Cleannlp, Taylor B. Arnold

Department of Math & Statistics Faculty Publications

Recent advances in natural language processing have produced libraries that extract low level features from a collection of raw texts. These features, known as annotations, are usually stored internally in hierarchical, tree-based data structures. This paper proposes a data model to represent annotations as a collection of normalized relational data tables optimized for exploratory data analysis and predictive modeling. The R package cleanNLP, which calls one of two state of the art NLP libraries (CoreNLP or spaCy), is presented as an implementation of this data model. It takes raw text as an input and returns a list of normalized tables. …

Mukaiyama Addition Of (Trimethylsilyl) Acetonitrile To Dimethyl Acetals Mediated By Trimethylsilyl Trifluoromethanesulfonate, C. Wade Downey, Alice Y.-K. Lee, John R. Goodin, Courtney J. Botelho, William M. Stith

Chemistry Faculty Publications

(Trimethylsilyl) acetonitrile reacts smoothly with dimethyl acetals in the presence of stoichiometric trimethylsilyl trifluoromethanesulfonate (TMSOTf) to yield β-methoxynitriles. The ideal substrates for this reaction are acetals derived from aromatic aldehydes. Elimination to the corresponding α,β-unsaturated nitriles is observed as the major product in the case of electron-rich acetals. A mechanistic hypothesis that includes isomerization of the silylnitrile to a nucleophilic N-silyl ketene imine is presented.

Gold Nanoparticle Colorants As Traditional Ceramic Glaze Alternatives, Raef H. Lambertson, Christie A. Lacy, Samuel D. Gillespie, Michael C. Leopold

Chemistry Faculty Publications

Historically, Roman stained glass has been a standard for high‐temperature color stability since biblical times but was not properly characterized as emission from nanoparticle plasmon resonance until the 1990s. The methods under which it was created have been lost, but some efforts have recently been made to recreate these properties using gold nanoparticle inks on glassy surfaces. This body of work employs gold nanoparticle systems ranging from 0.015% to 0.100% (wt/wt), suspended in a clear glaze body. The glazes are fired with traditional ceramic methods—in both gas reduction and electric oxidation kilns—in which nanoparticles are retained and can be imaged …

Pure E And B Polarization Maps Via Wiener Filtering, Emory F. Bunn, Benjamin Wandelt

Physics Faculty Publications

In order to draw scientific conclusions from observations of cosmic microwave background (CMB) polarization,it is necessary to separate the contributions of the E and B components of the data. For data with incomplete sky coverage, there are ambiguous modes, which can be sourced by either E or B signals. Techniques exist for producing “pure” E and B maps, which are guaranteed to be free of cross-contamination, although the standard method, which involves constructing an eigenbasis, has a high computational cost. We show that such pure maps can be thought of as resulting from the application of a Wiener filter to …

Agricultural Intensification Can Preserve The Brazilian Cerrado: Applying Lessons From Mato Grosso And Goia's To Brazil’S Last Agricultural Frontier, Stephanie A. Spera

Geography and the Environment Faculty Publications

Food security and climate change are two pressing issues shaping the future of tropical land use. Brazil, home to abundant land that is rich in carbon, water, and biodiversity and often cleared for agropastoral and renewable energy purposes, is the ideal location for studying socioeconomic and environmental trade-offs of land use dynamics. Here, I use recent (2000–2016) land-use land-cover change dynamics in the established agricultural states of Mato Grosso and Goia's to demonstrate how incentivizing intensive agricultural practices and improving degraded pastures may be a means by which Brazil can increase agricultural production while conserving the remainder of the Cerrado. …

A Unified Inter-Host And In-Host Model Of Antibiotic Resistance And Infection Spread In A Hospital Ward, Lester Caudill, Barry Lawson

Department of Math & Statistics Faculty Publications

As the battle continues against hospital-acquired infections and the concurrent rise in antibiotic resistance among many of the major causative pathogens, there is a dire need to conduct controlled experiments, in order to compare proposed control strategies. However, cost, time, and ethical considerations make this evaluation strategy either impractical or impossible to implement with living patients. This paper presents a multi-scale model that offers promise as the basis for a tool to simulate these (and other) controlled experiments. This is a “unified” model in two important ways: (i) It combines inter-host and in-host dynamics into a single model, and (ii) …

Mmtv-Pymt And Derived Met-1 Mouse Mammary Tumor Cells As Models For Studying The Role Of The Androgen Receptor In Triple-Negative Breast Cancer Progression, Jessica L. Christenson, Kiel T. Butterfield, Nicole S. Spoelstra, John D. Norris, Jatinder S. Josan, Julie A. Pollock, Donald P. Mcdonnell, Benita S. Katzenellenbogen, John A. Katzenellenbogen, Jennifer K. Richer

Chemistry Faculty Publications

Triple-negative breast cancer (TNBC) has a faster rate of metastasis compared to other breast cancer subtypes and no effective targeted therapies are currently FDA-approved. Recent data indicate that the androgen receptor (AR) promotes tumor survival and may serve as a potential therapeutic target in TNBC. Studies of AR in disease progression and the systemic effects of anti-androgens have been hindered by the lack of an AR-positive (AR+) immunocompetent preclinical model. In this study we identified the transgenic MMTV-PyMT (mouse mammary tumor virus-polyoma middle tumor antigen) mouse mammary gland carcinoma model of breast cancer and Met-1 cells derived from this model …

Precipitation Drivers Of Cropping Frequency In The Brazilian Cerrado: Evidence And Implications For Decision-Making, Keith R. Spangler, Amanda H. Lynch, Stephanie A. Spera

Geography and the Environment Faculty Publications

The Amazon basin has been subjected to unprecedented rates of land-use change over the past several decades, primarily as a result of the expansion of agriculture. Enhanced rain forest conservation efforts toward the end of the twentieth century slowed deforestation of the Amazon but, in turn, increased demand for land repurposing in the adjacent Cerrado (savanna) region, where conservation regulations are less strict. To maintain or increase yields while minimizing the need for additional land, agricultural producers adopted a form of intensification in which two rain-fed crops are planted within a single growing season (double cropping). Using 10 years (August …

Enzyme–Free Uric Acid Electrochemical Sensors Using Β–Cyclodextrin Modified Carboxylic Acid Functionalized Carbon Nanotubes, Mulugeta B. Wayu, Margaret A. Schwarzmann, Samuel D. Gillespie, Michael C. Leopold

Chemistry Faculty Publications

Carboxylic acid-functionalized multi-walled carbon nanotubes (COOH-MWCNT) were modified via ultrasonication with β-cyclodextrin (β-CD) to obtain a COOH-MWCNT:β-CD nanocomposite material for the purpose of developing an enzyme-free electrochemical sensor for uric acid—a clinically relevant molecule implemented in pregnancy-induced hypertension diagnosis. The nanocomposite material is deposited onto glassy carbon electrodes and subsequently capped with layers of Nafion and Hydrothane polyurethane. The surface morphology and electronic structure of the nanocomposite material were characterized using UV–Vis, TEM, and FTIR. The performance of the electrochemical sensor was measured through direct injection of UA during amperometry. With the high surface area of the COOH-MWCNT in concert …

The Relationship Between Tropical Cyclone Activity, Nutrient Loading, And Algal Blooms Over The Great Barrier Reef, Chelsea L. Parker, Amanda H. Lynch, Stephanie A. Spera, Keith R. Spangler

Geography and the Environment Faculty Publications

The Great Barrier Reef, the world’s largest coral reef ecosystem, is subject to many environmental stressors. This study utilizes remotely sensed Moderate Resolution Imaging Spectroradiometer (MODIS) chlorophyll a concentration data to explore statistically significant relationships between local-scale tropical cyclone disturbance and relative water quality between 2004–2014. The study reveals that tropical cyclone activity reduces water quality at 8- and 16-day time lags. Relationships suggest that at early stages (during and just after cyclone activity) algal response is induced primarily through wind-driven sediment re-suspension. However, wind speed in isolation only increases minimum levels of chlorophyll a, rather than mean or …

Analysis Of A Custom Support Vector Machine For Photometric Redshift Estimation And The Inclusion Of Galaxy Shape Information, Jack Singal, Evan Jones

Physics Faculty Publications

Aims. We present a custom support vector machine classification package for photometric redshift estimation, including comparisons with other methods. We also explore the efficacy of including galaxy shape information in redshift estimation. Support vector machines, a type of machine learning, utilize optimization theory and supervised learning algorithms to construct predictive models based on the information content of data in a way that can treat different input features symmetrically, which can be a useful estimator of the information contained in additional features beyond photometry, such as those describing the morphology of galaxies.

Methods. The custom support vector machine package we have …

A Comprehensive Analysis Of Team Streakiness In Major League Baseball: 1962-2016, Paul H. Kvam, Zezhong Chen

Department of Math & Statistics Faculty Publications

A baseball team would be considered “streaky” if its record exhibits an unusually high number of consecutive wins or losses, compared to what might be expected if the team’s performance does not really depend on whether or not they won their previous game. If an average team in Major League Baseball (i.e., with a record of 81-81) is not streaky, we assume its win probability would be stable at around 50% for most games, outside of peculiar details of day-to-day outcomes, such as whether the game is home or away, who is the starting pitcher, and so on.

In this …

Approaching Cauchy’S Theorem, Stephan Ramon Garcia, William T. Ross

Department of Math & Statistics Faculty Publications

We hope to initiate a discussion about various methods for introducing Cauchy’s Theorem. Although Cauchy’s Theorem is the fundamental theorem upon which complex analysis is based, there is no “standard approach.” The appropriate choice depends upon the prerequisites for the course and the level of rigor intended. Common methods include Green’s Theorem, Goursat’s Lemma, Leibniz’ Rule, and homotopy theory, each of which has its positives and negatives.

Multipliers Of Sequence Spaces, Raymond Cheng, Javad Mashreghi, William T. Ross

Department of Math & Statistics Faculty Publications

This paper is selective survey on the space l_A^p and its multipliers. It also includes some connections of multipliers to Birkhoff-James orthogonality.

Birkhoff–James Orthogonality And The Zeros Of An Analytic Function, Raymond Cheng, Javad Mashreghi, William T. Ross

Department of Math & Statistics Faculty Publications

Bounds are obtained for the zeros of an analytic function on a disk in terms of the Taylor coefficients of the function. These results are derived using the notion of Birkhoff–James orthogonality in the sequence space ℓ^p with p ∈ (1,∞), along with an associated Pythagorean theorem. It is shown that these methods are able to reproduce, and in some cases sharpen, some classical bounds for the roots of a polynomial.

Temperature Tuning From Direct To Inverted Bistable Electroluminescence In Resonant Tunneling Diodes, F. Hartmann, A. Pfenning, Mariama Rebello Sousa Dias, F. Langer, S. Höfling, M. Kamp, L. Worschech, L. K. Castelano, G. E. Marques, V. Lopez-Richard

Physics Faculty Publications

We study the electroluminescence (EL) emission of purely n-doped resonant tunneling diodes in a wide temperature range. The paper demonstrates that the EL originates from impact ionization and radiative recombination in the extended collector region of the tunneling device. Bistable currentvoltage response and EL are detected and their respective high and low states are tuned under varying temperature. The bistability of the EL intensity can be switched from direct to inverted with respect to the tunneling current and the optical on/off ratio can be enhanced with increasing temperature. One order of magnitude amplification of the optical on/off ratio can be …

The Biology Of Climate Change: The Effects Of Changing Climate On Migrating And Over-Wintering Species At A High-Elevation Field Station, Carrie A. Wu, Ellwein Amy

Biology Faculty Publications

Students engage with long-term environmental and phenology data sets (spanning over 40 years) collected at the Rocky Mountain Biological Laboratory, a high-elevation field station in Colorado, to explore the effects of climate change on the phenology of migrating and hibernating species. After becoming familiar with the geographic context, people involved with the data collection, and organisms studied through background readings and videos, students explore the raw data set in Excel or using an interactive data visualization tool. In small groups, students reproduce figures and regressions from Inouye et al. (2000) based on those data, then expand their analyses with data …

University Of Richmond Sustainability Report, Robert Andrejewski

Reports

The 2016 University of Richmond Sustainability Report represents where we are now, recognizes significant accomplishments, and provides a launching point for future endeavors. We all have a role to play in the continued stewardship of this great place.

This document presents a summary of the data we collected. It serves the dual role of providing information on the considerable sustainability efforts underway and establishes a benchmark for our efforts as we move forward. There is much to be celebrated, and there is much to be done.

A New Almost Difference Set Construction, David Clayton

Honors Theses

This paper considers the appearance of almost difference sets in non-abelian groups. While numerous construction methods for these structures are known in abelian groups, little is known about ADSs in the case where the group elements do not commute. This paper presents a construction method for combining abelian difference sets into nonabelian almost difference sets, while also showing that at least one known almost difference set construction can be generalized to the nonabelian case.

Study Of The Neutron Detection Efficiency Of The Clas12 Detector, Keegan Sherman

Honors Theses

One of the central physics goals of Jefferson Lab is to understand how quarks and gluons form nuclei. The 12 GeV upgrade is nearing completion and a new detector, CLAS12, is being built in Hall B. One of the approved experiments will measure the magnetic form factor of the neutron (Gn ). To make this measurement, the ratio of electron-neutron (e-n) to electron-proton (e-p) scattering events will be extracted from deuterium in quasi-elastic kinematics. A major source of systematic uncertainty is the neutron detection efficiency (NDE) of CLAS12. To better understand the NDE I used the Monte Carlo …

Justice And Equity In Carbon Offset Governance: Debates And Dilemmas, Mary Finley-Brook

Geography and the Environment Faculty Publications

Trade-offs complicate development interventions so that benefits for one group or area often imply costs for another; large-scale projects deemed highly efficient in economic terms may generate harmful environmental or social externalities. This chapter explores issues of justice in carbon trading in terms of decision-making power and the subsequent distribution of positive and negative impacts. It explores whether offset governance can help resolve widespread problems, such as racial or income inequality and environmental injustice.

Quantum Groups And Knot Invariants, Greg A. Hamilton

Honors Theses

Knot theory arguably holds claim to the title of the mathematical discipline with the most unusually diverse applications. A knot can be defined topologically as an embedding of S1 in R3. Naturally, two knots are topologically equivalent if one cannot be smoothly deformed into the other. The question of whether two knots are equivalent is highly non-trivial, and so the question of knot invariants used to distinguish knots has occupied knot theorists for over a century. Knot theory has found application in statistical mechanics [1], symbolic logic and set theory [2], quantum fi theory [3], quantum computing [4], etc. …

Differential Privacy For Growing Databases, Gi Heung (Robin) Kim

Honors Theses

Differential privacy [DMNS06] is a strong definition of database privacy that provides indi- viduals in a database with the guarantee that any particular person’s information has very little effect on the output of any analysis of the overall database. In order for this type of analysis to be practical, it must simultaneously preserve privacy and utility, where utility refers to how well the analysis describes the contents of the database.

An analyst may additionally wish to evaluate how a database’s composition changes over time. Consider a company, for example, that accumulates data from a growing base of customers. This company …

Toward A Scientific Investigation Of Convolutional Neural Networks, Anh Tran

Honors Theses

This thesis does not assume the reader is familiar with artificial neural networks. However, to keep the thesis concise, it assumes the reader is familiar with the standard Machine Learning concepts of training set, validation set, and test set [1]. Their usage is intended to help ensure that the Machine Learning system can generalize its training from input examples used during its training to “similar” kinds of examples never used during its training.

The concept of a Convolutional Neural Network (CNN) is one of the most successful computational concepts today for solving image classification problems. However, CNNs are difficult and …

Differential Equations Models Of Pathogen-Induced Single- And Multi-Organ Tissue Damage, Fiona Lynch

Honors Theses

The rise of antibiotic resistance has created a significant burden on healthcare systems around the world. Antibiotic resistance arises from the increased use of antibiotic drugs and antimicrobial agents, which kill susceptible bacterial strains, but have little effect on strains that have a mutation allowing them to survive antibiotic treatment, defined as “resistant” strains. With no non-resistant bacteria to compete for resources, the resistant bacteria thrives in this environment, continuing to reproduce and infect the host with an infection that does not respond to traditional antibiotic treatment.

A number of strategies have been proposed to tackle the problem of antibiotic …

Investigating Medicinally Important Portein-Protein And Protein-Ligand Interactions : A Computational Approach, Cooper Ashley Taylor

Honors Theses

Molecular dynamics (MD) simulations and computational chemistry allow for an atomistic understanding of protein-protein and protein-ligand binding motifs. Through the use of MD, medicinally relevant complexes can be examined in detail unattainable by experimental methods. Within this work, systems pertinent to both Alzheimer’s Disease and HIV-1 are probed and thoroughly sampled to help elucidate potential therapeutic pathways. We used molecular dynamics and free energy estimations to gauge the affinity for the binary and ternary complexes of KLC1, APP and JIP1, three proteins all believed to be involved in the propagation of Alzheimer’s Disease. Two areas of thought exist suggesting that …