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Full-Text Articles in Physical Sciences and Mathematics

College Of Engineering Senior Design Competition Fall 2012, University Of Nevada, Las Vegas Dec 2012

College Of Engineering Senior Design Competition Fall 2012, University Of Nevada, Las Vegas

Fred and Harriet Cox Senior Design Competition Projects

Senior Design Experience

Part of every UNLV engineering student's academic experience, the Senior Design project stimulates engineering innovation and entrepreneurship. Each student in their senior year chooses, plans, designs and prototypes a product in this required element of the curriculum. Working in teams, the senior design project encourages students to use everything learned in the engineering and computer design programs to create a practical, real world solution to an engineering challenge.

Beyond the classroom ...

Because of the requirement to work in teams, students also build good communication skills, presentation skills and even business writing skills. They also have to …


Secondary Structure, A Missing Component Of Sequence- Based Minimotif Definitions, David P. Sargeant, Michael R. Gryk, Mark W. Maciejewsk, Vishal Thapar, Vamsi Kundeti, Sanguthevar Rajasekaran, Pedro Romero, Keith Dunker, Shun-Cheng Li, Tomonori Kaneko, Martin Schiller Dec 2012

Secondary Structure, A Missing Component Of Sequence- Based Minimotif Definitions, David P. Sargeant, Michael R. Gryk, Mark W. Maciejewsk, Vishal Thapar, Vamsi Kundeti, Sanguthevar Rajasekaran, Pedro Romero, Keith Dunker, Shun-Cheng Li, Tomonori Kaneko, Martin Schiller

Life Sciences Faculty Research

Minimotifs are short contiguous segments of proteins that have a known biological function. The hundreds of thousands of minimotifs discovered thus far are an important part of the theoretical understanding of the specificity of protein-protein interactions, posttranslational modifications, and signal transduction that occur in cells. However, a longstanding problem is that the different abstractions of the sequence definitions do not accurately capture the specificity, despite decades of effort by many labs. We present evidence that structure is an essential component of minimotif specificity, yet is not used in minimotif definitions. Our analysis of several known minimotifs as case studies, analysis …


Linked Data Demystified: Practical Efforts To Transform Contentdm Metadata For The Linked Data Cloud, Silvia B. Southwick, Cory K. Lampert Nov 2012

Linked Data Demystified: Practical Efforts To Transform Contentdm Metadata For The Linked Data Cloud, Silvia B. Southwick, Cory K. Lampert

Library Faculty Presentations

The library literature and events like the ALA Annual Conference have been inundated with presentations and articles on linked data. At UNLV Libraries, we understand the importance of linked data in helping to better service our users. We have designed and initiated a pilot project to apply linked data concepts to the practical task of transforming a sample set of our CONTENTdm digital collections data into future-oriented linked data. This presentation will outline rationale for beginning work in linked data and detail the phases we will undertake in the proof of concept project. We hope through this research experiment to …


Apps And Apple Devices: Productive Icloud Uses, Cyrus Ford Zarganj Oct 2012

Apps And Apple Devices: Productive Icloud Uses, Cyrus Ford Zarganj

Library Faculty Presentations

This program introduces useful apps for librarians who have two or more Apple devices such as an iPhone, iPad, or MacBook. You can learn how to use the iCloud, sync devices together, and about other useful apps for librarians to work on their projects from different places with different Apple devices without carrying files.


Achieving High Accuracy Prediction Of Minimotifs, Tian Mi, Sanguthevar Rajasekaran, Jerlin Camilus Merlin, Michael R. Gryk, Martin Schiller Sep 2012

Achieving High Accuracy Prediction Of Minimotifs, Tian Mi, Sanguthevar Rajasekaran, Jerlin Camilus Merlin, Michael R. Gryk, Martin Schiller

Life Sciences Faculty Research

The low complexity of minimotif patterns results in a high false-positive prediction rate, hampering protein function prediction. A multi-filter algorithm, trained and tested on a linear regression model, support vector machine model, and neural network model, using a large dataset of verified minimotifs, vastly improves minimotif prediction accuracy while generating few false positives. An optimal threshold for the best accuracy reaches an overall accuracy above 90%, while a stringent threshold for the best specificity generates less than 1% false positives or even no false positives and still produces more than 90% true positives for the linear regression and neural network …


College Of Engineering Senior Design Competition Spring 2012, University Of Nevada, Las Vegas May 2012

College Of Engineering Senior Design Competition Spring 2012, University Of Nevada, Las Vegas

Fred and Harriet Cox Senior Design Competition Projects

Senior Design Experience

Part of every UNLV engineering student’s academic experience, the Senior Design project stimulates engineering innovation and entrepreneurship. Each student in their senior year chooses, plans, designs and prototypes a product in this required element of the curriculum. Working in teams, the senior design project encourages students to use everything learned in the engineering and computer design programs to create a practical, real world solution to an engineering challenge.

Beyond the classroom...

Because of the requirement to work in teams, students also build good communication skills, presentation skills and even business writing skills. They also have to source …


College Of Engineering Senior Design Competition Spring 2018, University Of Nevada, Las Vegas May 2012

College Of Engineering Senior Design Competition Spring 2018, University Of Nevada, Las Vegas

Fred and Harriet Cox Senior Design Competition Projects

Part of every UNLV engineering student’s academic experience, the senior design project stimulates engineering innovation and entrepreneurship. Each student in their senior year chooses, plans, designs, and prototypes a product in this required element of the curriculum. A capstone to the student’s educational career, the senior design project encourages the student to use everything learned in the engineering program to create a practical, real world solution to an engineering challenge. The senior design competition helps focus the senior students in increasing the quality and potential for commercial application for their design projects. Judges from local industry evaluate the projects on …


Losing The Lake: Development And Deployment Of An Educational Game, Joseph M. Vesco, Katie Gilgen, Anne Paine, Marissa Owens, Michael Nussbaum, Gale M. Sinatra, Sajjad Ahmad, Kent J. Crippen, Sergiu Dascalu, Frederick C. Harris Mar 2012

Losing The Lake: Development And Deployment Of An Educational Game, Joseph M. Vesco, Katie Gilgen, Anne Paine, Marissa Owens, Michael Nussbaum, Gale M. Sinatra, Sajjad Ahmad, Kent J. Crippen, Sergiu Dascalu, Frederick C. Harris

Civil and Environmental Engineering and Construction Faculty Research

When asked what the top three issues of the Las Vegas region were, the reply was “water, water, water!" This was the result of a survey done a few years ago of Las Vegas Valley TV anchors. The reason for this response is that sustainability of the urban environments requires sufficient water resources as does population growth. With the advent of global climate change, this resource is in danger. Water flow and mountainous ice packs are impacted by this change in climate there by impacting the amount of water the the region. This is compounded over time as the population …


Minimotif Miner 3.0: Database Expansion And Significantly Improved Reduction Of False-Positive Predictions From Consensus Sequences., Tian Mi, Jerlin Camilus Merlin, Sandeep Deverasetty, Michael R. Gryk, Travis J. Bill, Andrew W. Brooks, Logan Lee, Viraj Rathnayake, Christian A. Ross, David P. Sargeant, Christy L. Strong, Paula Watts, Sanguthevar Rajasekaran, Martin Schiller Jan 2012

Minimotif Miner 3.0: Database Expansion And Significantly Improved Reduction Of False-Positive Predictions From Consensus Sequences., Tian Mi, Jerlin Camilus Merlin, Sandeep Deverasetty, Michael R. Gryk, Travis J. Bill, Andrew W. Brooks, Logan Lee, Viraj Rathnayake, Christian A. Ross, David P. Sargeant, Christy L. Strong, Paula Watts, Sanguthevar Rajasekaran, Martin Schiller

Life Sciences Faculty Research

Minimotif Miner (MnM available at http://minimotifminer.org or http://mnm.engr.uconn.edu) is an online database for identifying new minimotifs in protein queries. Minimotifs are short contiguous peptide sequences that have a known function in at least one protein. Here we report the third release of the MnM database which has now grown 60-fold to approximately 300,000 minimotifs. Since short minimotifs are by their nature not very complex we also summarize a new set of false-positive filters and linear regression scoring that vastly enhance minimotif prediction accuracy on a test data set. This online database can be used to predict new functions in proteins …