Physical Sciences and Mathematics Commons^™

The Basil Technique: Bias Adaptive Statistical Inference Learning Agents For Learning From Human Feedback, Jonathan Indigo Watson

Theses and Dissertations--Computer Science

We introduce a novel approach for learning behaviors using human-provided feedback that is subject to systematic bias. Our method, known as BASIL, models the feedback signal as a combination of a heuristic evaluation of an action's utility and a probabilistically-drawn bias value, characterized by unknown parameters. We present both the general framework for our technique and specific algorithms for biases drawn from a normal distribution. We evaluate our approach across various environments and tasks, comparing it to interactive and non-interactive machine learning methods, including deep learning techniques, using human trainers and a synthetic oracle with feedback distorted to varying degrees. …

Impact Of Home Visit Capacity On Genetic Association Studies Of Late-Onset Alzheimer's Disease, David W. Fardo, Laura E. Gibbons, Shubhabrata Mukherjee, M. Maria Glymour, Wayne Mccormick, Susan M. Mccurry, James D. Bowen, Eric B. Larson, Paul K. Crane

Biostatistics Faculty Publications

INTRODUCTION—Findings for genetic correlates of late-onset Alzheimer's disease (LOAD) in studies that rely solely on clinic visits may differ from those with capacity to follow participants unable to attend clinic visits.

METHODS—We evaluated previously identified LOAD-risk single nucleotide variants in the prospective Adult Changes in Thought study, comparing hazard ratios (HRs) estimated using the full data set of both in-home and clinic visits (n = 1697) to HRs estimated using only data that were obtained from clinic visits (n = 1308). Models were adjusted for age, sex, principal components to account for ancestry, and additional health indicators.

RESULTS …