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Full-Text Articles in Physical Sciences and Mathematics
The Determination Of Biological Activity And Biochemical Mode Of Action For The Oxadiazole And Diacylhdrazine Insecticides, Bonnie M. Gunn
The Determination Of Biological Activity And Biochemical Mode Of Action For The Oxadiazole And Diacylhdrazine Insecticides, Bonnie M. Gunn
Retrospective Theses and Dissertations
This report includes the determination of activity and possible mode of action for a group of potential new insecticides. The biological screening procedure was developed using Drosophila melanogaster as the test organism while Musca domestica was used for mode of action assays. The percent kill for each compound is based on the number of eggs placed on media containing the insecticide minus the number of adults enclosed as compared to the control media reared flies. Observations were made on all stages from eggs through adults to determine time of death and if any malformations were present. These observations aided in …
Part I: The Synthesis Of Potential Agrochemicals. Part Ii: The Use Of Gold's Reagent As A Lynch Pin In The Formation Of Five And Six Membered Heterocycles, Keith F. Correia
Part I: The Synthesis Of Potential Agrochemicals. Part Ii: The Use Of Gold's Reagent As A Lynch Pin In The Formation Of Five And Six Membered Heterocycles, Keith F. Correia
Retrospective Theses and Dissertations
This research report focuses on two topics: the synthesis of potential agrochemicals and the use of Gold's reagent as a lynch pin to form five- and six-membered heterocycles. A diacyl hydrazide and two oxadiazoles are prepared for use as possible insecticides. Gold's reagent behaves as a one-atom and two-atom lynch pin when reacted with 1, 4- and 1, 5-dinucleophiles, respectively. Reaction conditions, interpretation of spectral data, and recommendations for further research are provided.
Part I: The Synthesis Of New Potential Insecticides. Part Ii: New Aromatic Nucleophililic Subsitution Reactions, Fluoroalkoxylation And N,N-Dimethylamination, Cesar Colon
Retrospective Theses and Dissertations
A series of routes are described for the synthesis of new potential insecticides which are symmetrical or asymmetrical similogs of 2,5-Bis (dichloropheny1)-1,3,4-oxadiazole and its precursor diacyl hydrazine. Also two new aromatic nucleophilic substitution reactions are discussed. Activated aryl halides are reacted with fluorinated alkoxide anions. In all cases, substitution of the halogen by a fluoroalkoxy group was observed, and activated aryl halides are reacted with HMPA as an N, N-dimethyl aminating agent. In all cases, substitution of the halogen by a dimethyl amino group was observed. The effect of the activating group and the leaving group is described and a …
Synthesis Of Potential Insecticides And New Synthetic Applications Of Vinamidinium And Azavinamidinium Salts: Reactions With Reducing Agents And Nitro Compounds, Michael J. Lizzi
Synthesis Of Potential Insecticides And New Synthetic Applications Of Vinamidinium And Azavinamidinium Salts: Reactions With Reducing Agents And Nitro Compounds, Michael J. Lizzi
Retrospective Theses and Dissertations
This report discusses the research conducted in two areas: the synthesis of potential insecticides and the investigation of vinamidinium and azavinamidinium salt chemistry. Firstly, four classes of compounds were synthesized and characterized in the investigation of new potential insecticides. These classes of compounds include a-formamidine methyl esters, amidines, diacylhydrazines and 2,5-disubstituted-1,3,4-oxadiazoles and were characterized via NMR and infrared spectroscopy. This account also reveals and discusses the experimental conditions and procedures necessary for the preparation of these potential insecticides. Secondly, the reaction of [ 3-(dimethyl amino)-2-azaprop-2-en-1-ylidene] dimethyl ammonium chloride (Gold's Reagent) with nucleophiles such as activated (nitro) methylene compounds was examined …