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Full-Text Articles in Physical Sciences and Mathematics

An Autoencoder-Based Deep Learning Method For Genotype Imputation, Meng Song, Jonathan Greenbaum, Joseph Luttrell Iv, Weihua Zhou, Chong Wu, Zhe Luo, Chuan Qiu, Lan Juan Zhao, Kuan-Jui Su, Qing Tian, Hui Shen, Huixiao Hong, Ping Gong, Xinghua Shi, Hong-Wen Deng, Chaoyang Zhang Nov 2022

An Autoencoder-Based Deep Learning Method For Genotype Imputation, Meng Song, Jonathan Greenbaum, Joseph Luttrell Iv, Weihua Zhou, Chong Wu, Zhe Luo, Chuan Qiu, Lan Juan Zhao, Kuan-Jui Su, Qing Tian, Hui Shen, Huixiao Hong, Ping Gong, Xinghua Shi, Hong-Wen Deng, Chaoyang Zhang

Faculty Publications

Genotype imputation has a wide range of applications in genome-wide association study (GWAS), including increasing the statistical power of association tests, discovering trait-associated loci in meta-analyses, and prioritizing causal variants with fine-mapping. In recent years, deep learning (DL) based methods, such as sparse convolutional denoising autoencoder (SCDA), have been developed for genotype imputation. However, it remains a challenging task to optimize the learning process in DL-based methods to achieve high imputation accuracy. To address this challenge, we have developed a convolutional autoencoder (AE) model for genotype imputation and implemented a customized training loop by modifying the training process with a …


On The Spatial Variability Of The Mesoscale Sea Surface Height Wavenumber Spectra In The Atlantic Ocean, Xiaobiao Xu, Eric P. Chassignet, Alan J. Wallcraft, Brian K. Arbic, Maarten C. Buijsman, Miguel Solano Oct 2022

On The Spatial Variability Of The Mesoscale Sea Surface Height Wavenumber Spectra In The Atlantic Ocean, Xiaobiao Xu, Eric P. Chassignet, Alan J. Wallcraft, Brian K. Arbic, Maarten C. Buijsman, Miguel Solano

Faculty Publications

The wavenumber spectral slope of sea surface height (SSH) computed within the mesoscale range (70–250 km) from satellite altimetry exhibits a large spatial variability which, until now, has not been reproduced in numerical ocean models. This study documents the impacts of including internal tides, high-resolution bathymetry, and high-frequency atmospheric variability on the SSH wavenumber spectra in the Atlantic Ocean, using a series of 1/50° North and equatorial Atlantic simulations with a realistic representation of barotropic/baroclinic tides and mesoscale-to-submesoscale variability. The results show that the inclusion of internal tides does increase high frequency SSH variability (with clear peaks near 120 and …


Solving Inverse Conductivity Problems In Doubly Connected Domains By The Homogenization Functions Of Two Parameters, Jun Lu, Lianpeng Shi, Chein-Shan Liu, C.S. Chen Jun 2022

Solving Inverse Conductivity Problems In Doubly Connected Domains By The Homogenization Functions Of Two Parameters, Jun Lu, Lianpeng Shi, Chein-Shan Liu, C.S. Chen

Faculty Publications

In the paper, we make the first attempt to derive a family of two-parameter homogenization functions in the doubly connected domain, which is then applied as the bases of trial solutions for the inverse conductivity problems. The expansion coefficients are obtained by imposing an extra boundary condition on the inner boundary, which results in a linear system for the interpolation of the solution in a weighted Sobolev space. Then, we retrieve the spatial- or temperature-dependent conductivity function by solving a linear system, which is obtained from the collocation method applied to the nonlinear elliptic equation after inserting the solution. Although …


Near-Inertial Wave Energetics Modulated By Background Flows In A Global Model Simulation, Keshav J. Raja, Maarten J. Buijsman, Jay F. Shriver, Brian K. Arbic, Oladeji Siyanbola May 2022

Near-Inertial Wave Energetics Modulated By Background Flows In A Global Model Simulation, Keshav J. Raja, Maarten J. Buijsman, Jay F. Shriver, Brian K. Arbic, Oladeji Siyanbola

Faculty Publications

We study the generation, propagation, and dissipation of wind-generated near-inertial waves (NIWs) in a global 1/25° Hybrid Coordinate Ocean Model (HYCOM) simulation with realistic atmospheric forcing and background circulation during 30 days in May–June 2019. The time-mean near-inertial wind power input and depth-integrated energy balance terms are computed for the total fields and the fields decomposed into vertical modes to differentiate between the radiative and (locally) dissipative components of NIW energy. Only 30.3% of the near-inertial wind input projects onto the first five modes, whereas the sum of the NIW energy in the first five modes adds up to 58% …


Dispersed Crude Oil Induces Dysbiosis In The Red Snapper Lutjanus Campechanus External Microbiota, Andrew M. Tarnecki, Christelle Miller, Tracy A. Sherwood, Robert J. Griffitt, Ryan W. Schloesser, Dana L. Wetzel Jan 2022

Dispersed Crude Oil Induces Dysbiosis In The Red Snapper Lutjanus Campechanus External Microbiota, Andrew M. Tarnecki, Christelle Miller, Tracy A. Sherwood, Robert J. Griffitt, Ryan W. Schloesser, Dana L. Wetzel

Faculty Publications

The fish external microbiota competitively excludes primary pathogens and prevents the proliferation of opportunists. A shift from healthy microbiota composition, known as dysbiosis, may be triggered by environmental stressors and increases host susceptibility to disease. The Deepwater Horizon (DWH) oil spill was a significant stressor event in the Gulf of Mexico. Despite anecdotal reports of skin lesions on fishes following the oil spill, little information is available on the impact of dispersed oil on the fish external microbiota. In this study, juvenile red snapper (Lutjanus campechanus) were exposed to a chemically enhanced water-accommodated fraction (CEWAF) of Corexit 9500/DWH …


Mid-Breton Sediment Diversion (Mbrsd) Assessment – Final Report, Jerry D. Wiggert, Brandy N. Armstrong, M. Kemal Cambazoglu, Sandeep Kalathupurath Kuttan Jan 2022

Mid-Breton Sediment Diversion (Mbrsd) Assessment – Final Report, Jerry D. Wiggert, Brandy N. Armstrong, M. Kemal Cambazoglu, Sandeep Kalathupurath Kuttan

Faculty Publications

The purpose of this project is to provide managers at the Mississippi Department of Marine Resources (MDMR) with the scientific information needed to accurately address public concerns regarding the potential effects of the Louisiana Coastal Master Plan / Coastal Protection and Restoration Authority (CPRA) Mid-Breton Sediment Diversion (MBrSD) on the jurisdictional waters and resources of Mississippi. The stated design purpose of the MBrSD is to reconnect and re-establish the deltaic sediment deposition process between the Mississippi River and the Breton Sound Basin through a diversion that will deliver up to 75,000 cfs of sediment-laden freshwater. The report presented herein provides …