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Syracuse University

2011

Anti-biofouling chemistry

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Controlling Biofouling By Surface Engineering And Molecular Inhibition, Debjyoti Bandyopadhyay Dec 2011

Controlling Biofouling By Surface Engineering And Molecular Inhibition, Debjyoti Bandyopadhyay

Chemistry - Dissertations

The common theme that binds together all the chapters in this dissertation is anti-biofouling chemistry. By utilizing tools of surface engineering and molecular inhibition, a hypothesis driven, systematic approach of controlling the different forms of biofoulings such as protein adsorption, mammalian cell adhesion and biofilm formation is presented. Chapter 1 provides a brief introduction about topics relevant for understanding the studies presented in subsequent chapters. Chapter 2 reports the synthesis of enantiomerically pure alkanethiols that terminate with different stereoisomer's of sugar alcohols, and the effect of chirality of these polyol-terminated self-assembled monolayers (SAMs) on resisting protein adsorption.

Chapter 3 …