Physical Sciences and Mathematics Commons^™

A Computational Model For Recovery From Brain Injury, Wayne Wakeland

Systems Science Friday Noon Seminar Series

A computational simulation model calculates recovery trajectories following traumatic brain injury (TBI). Prior publications include a multi-scale framework for studying concussion and a systems-level causal loop diagram (CLD) and discussion of feedback processes. The scope of the computational model goes beyond concussion to include all severities of TBI. A set of first order ordinary differential equations and their associated parameters determines recovery trajectories. While highly speculative, the model serves to demonstrate the potential utility of computational models in this context. Much more research will be needed to create a properly supported research model that could be used for clinical trial …

A Computational Model For Recovery From Traumatic Brain Injury, Wayne Wakeland, Erin S. Kenzie

Systems Science Faculty Publications and Presentations

A computational simulation model calculates estimated recovery trajectories following traumatic brain injury (TBI). Prior publications include a multi-scale conceptual framework for studying concussion, a systems-level causal loop diagram (CLD) and an analysis of key feedback processes. A set of first order ordinary differential equations and their associated parameters determines recovery trajectories. The model contains 15 state variables, 73 auxiliary variables, and 50 parameters describing TBI pathology in an aggregate fashion at the cellular, network, cognitive and social levels. There are 1200 feedback loops, which give rise to a variety of behavior modes, many of which are highly nonlinear. Exogenous parameters …

Systems Thinking As A Design Process, Elizabeth Lockwood

Systems Science Friday Noon Seminar Series

During my master’s degree I analyzed sustainable practices in the built environment. What came from that work was a deep level of understanding that the current practices and rating systems appeared to be technical approaches to a larger system at play. I realized I have a gift to see hidden connections and find links between systems. Currently I use systems mapping as part of the design process to unearth the hidden elements in a system. I believe it is important to understand where designers, clients and stakeholders can insert themselves into a system. Part of this understanding is having empathy …

Latent Space Models For Temporal Networks, Jasper Alt

Systems Science Friday Noon Seminar Series

In many contexts we may expect the structure of networks to be derived from some kind of abstract distance between actors. We refer to this phenomenon as homophily: like nodes connect to like. For example, people with similar beliefs may be more likely to form social relations.

We formalize this notion by positioning the nodes in a latent space representing the possible values of the homophilous attributes. Realistically, we should expect latent attributes like beliefs to change over time in some nontrivial way, and the structures of temporal networks to evolve accordingly. We introduce a model of latent space dynamics …