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Full-Text Articles in Physical Sciences and Mathematics

System Dynamics Modeling For Traumatic Brain Injury: Mini-Review Of Applications, Erin S. Kenzie, Elle L. Parks, Nancy Carney, Wayne Wakeland Aug 2022

System Dynamics Modeling For Traumatic Brain Injury: Mini-Review Of Applications, Erin S. Kenzie, Elle L. Parks, Nancy Carney, Wayne Wakeland

Systems Science Faculty Publications and Presentations

Traumatic brain injury (TBI) is a highly complex phenomenon involving a cascade of disruptions across biomechanical, neurochemical, neurological, cognitive, emotional, and social systems. Researchers and clinicians urgently need a rigorous conceptualization of brain injury that encompasses nonlinear and mutually causal relations among the factors involved, as well as sources of individual variation in recovery trajectories. System dynamics, an approach from systems science, has been used for decades in fields such as management and ecology to model nonlinear feedback dynamics in complex systems. In this mini-review, we summarize some recent uses of this approach to better understand acute injury mechanisms, recovery …


Reducing Opioid Use Disorder And Overdose Deaths In The United States: A Dynamic Modeling Analysis, Erin J. Stringfellow, Tse Yang Lim, Keith Humphreys, Catherine Digennero, Celia Stafford, Elizabeth Beaulieu, Jack Homer, Wayne Wakeland, Multiple Additional Authors Jun 2022

Reducing Opioid Use Disorder And Overdose Deaths In The United States: A Dynamic Modeling Analysis, Erin J. Stringfellow, Tse Yang Lim, Keith Humphreys, Catherine Digennero, Celia Stafford, Elizabeth Beaulieu, Jack Homer, Wayne Wakeland, Multiple Additional Authors

Systems Science Faculty Publications and Presentations

Opioid overdose deaths remain a major public health crisis. We used a system dynamics simulation model of the U.S. opioid-using population age 12 and older to explore the impacts of 11 strategies on the prevalence of opioid use disorder (OUD) and fatal opioid overdoses from 2022 to 2032. These strategies spanned opioid misuse and OUD prevention, buprenorphine capacity, recovery support, and overdose harm reduction. By 2032, three strategies saved the most lives: (i) reducing the risk of opioid overdose involving fentanyl use, which may be achieved through fentanyl-focused harm reduction services; (ii) increasing naloxone distribution to people who use opioids; …


A New Agent-Based Model Offers Insight Into Population-Wide Adoption Of Prosocial Common-Pool Behavior, Garry Sotnik, Thaddeus Shannon, Wayne Wakeland Feb 2022

A New Agent-Based Model Offers Insight Into Population-Wide Adoption Of Prosocial Common-Pool Behavior, Garry Sotnik, Thaddeus Shannon, Wayne Wakeland

Systems Science Faculty Publications and Presentations

New theoretical agent-based model of population-wide adoption of prosocial common-pool behavior with four parameters (initial percent of adopters, pressure to change behavior, synergy from behavior, and population density); dynamics in behavior, movement, freeriding, and group composition and size; and emergence of multilevel group selection. Theoretical analysis of model’s dynamics identified six regions in model’s parameter space, in which pressure-synergy combinations lead to different outcomes: extinction, persistence, and full adoption. Simulation results verified the theoretical analysis and demonstrated that increases in density reduce number of pressure-synergy combinations leading to population-wide adoption; initial percent of contributors affects underlying behavior and final outcomes, …


Reconstructability Analysis: Discrete Multivariate Modeling, Martin Zwick Jan 2022

Reconstructability Analysis: Discrete Multivariate Modeling, Martin Zwick

Systems Science Faculty Publications and Presentations

An introduction to Reconstructability Analysis for the Discrete Multivariate Modeling course and for other purposes.