Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
Experimental Design, Synthesis And Application Of Molecular Micelle Modified Polymeric Nanoparticles For Drug Delivery Systems And Free Radical Detection, Gabriela M. Ganea Visser
Experimental Design, Synthesis And Application Of Molecular Micelle Modified Polymeric Nanoparticles For Drug Delivery Systems And Free Radical Detection, Gabriela M. Ganea Visser
LSU Doctoral Dissertations
Biodegradable and biocompatible polymeric nanoparticles such as poly (lactide-co-glycolide) (PLGA) nanoparticles have been extensively studied as drug delivery systems for a variety of pharmaceutical agents. Nanoparticle surface properties are primarily determined by the emulsifiers used in the synthesis process, which have a significant impact on nanoparticle physico-chemical and biological properties. Anionic amino acid – based molecular micelles were used in the emulsification process to prepare monodisperse, small (below 100 nm) PLGA nanoparticles with a well defined spherical shape. Such molecular micelle – modified nanoparticles were used as drug carriers for delivery of antioxidants. Thymoquinone is a natural antioxidant, and an …
Impact Of Intrafraction Motion On Post-Mastectomy Tomotherapy Of The Chest Wall, Shima Ito
Impact Of Intrafraction Motion On Post-Mastectomy Tomotherapy Of The Chest Wall, Shima Ito
LSU Master's Theses
Purpose: The present work investigates the impact of intrafraction motion of the chest wall due to respiration on Post Mastectomy Radiotherapy (PMRT) with TomoTherapy. The hypothesis of this work is that the impact of intrafraction motion on TomoTherapy PMRT will be insignificant as (1) the largest intrafraction movement of the chest wall (CW) in the medial-lateral, anterior-posterior, and superior-inferior dimensions will not exceed 1 cm and (2) that 95% of in-vivo CW point doses on the patient surface will be within 5% of calculated dose and all doses within 10% of calculated dose. Methods: 4DCT scans were acquired and intrafraction …