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Full-Text Articles in Physical Sciences and Mathematics
Semi-Parametric Inference For The Partial Area Under The Roc Curve, Fangfang Sun
Semi-Parametric Inference For The Partial Area Under The Roc Curve, Fangfang Sun
Mathematics Theses
Diagnostic tests are central in the field of modern medicine. One of the main factors for interpreting a diagnostic test is the discriminatory accuracy. For a continuous-scale diagnostic test, the area under the receiver operating characteristic (ROC) curve, AUC, is a useful one-number summary index for the diagnostic accuracy of the test. When only a particular region of the ROC curve would be of interest, the partial AUC (pAUC) is a more appropriate index for the diagnostic accuracy. In this thesis, we develop seven confidence intervals for the pAUC under the semi-parametric models for the diseased and non-diseased populations by …
Empirical Likelihood Based Confidence Intervals For The Difference Between Two Sensitivities Of Continuous-Scale Diagnostic Tests At A Fixed Level Of Specificity, Suqin Yao
Mathematics Theses
Diagnostic testing is essential to distinguish non-diseased individuals from diseased individuals. The sensitivity and specificity are two important indices for the diagnostic accuracy of continuous-scale diagnostic tests. If we want to compare the effectiveness of two tests, it is of interest to construct a confidence interval for the difference of the two sensitivities at a fixed level of specificity. In this thesis, we propose two empirical likelihood based confidence intervals (HBELI and HBELII) for the difference of two sensitivities at a predetermined specificity level. Simulation studies show that when correlation between the two test results exists, HBELI and HBELII intervals …