Physical Sciences and Mathematics Commons^™

Analyzing Marriage Statistics As Recorded In The Journal Of The American Statistical Association From 1889 To 2012, Annalee Soohoo

CMC Senior Theses

The United States has been tracking American marriage statistics since its founding. According to the United States Census Bureau, “marital status and marital history data help federal agencies understand marriage trends, forecast future needs of programs that have spousal benefits, and measure the effects of policies and programs that focus on the well-being of families, including tax policies and financial assistance programs.”[1] With such a wide scope of applications, it is understandable why marriage statistics are so highly studied and well-documented.

This thesis will analyze American marriage patterns over the past 100 years as documented in the Journal of …

Mary Eleanor Spear's Importance To The History Of Statistical Visualization, Melanie Williams

CMC Senior Theses

This paper will demonstrate why Mary Eleanor Spear (1897-1986) is an important figure in the history of statistical visualization. She lead an impressive career working in the federal government as a data analyst before "data analyst" became a thing. She wrote and illustrated two comprehensive textbooks which furthered the art of statistical visualization. Her textbooks cover extensive graphing knowledge still valuable to statisticians and viewers today. Most notable of her works is her development of the box plot. In addition to Spear's career and contributions, this paper will also address the lack of female representation in science, technology, engineering, and …

Bayesian Hierarchical Meta-Analysis Of Asymptomatic Ebola Seroprevalence, Peter Brody-Moore

CMC Senior Theses

The continued study of asymptomatic Ebolavirus infection is necessary to develop a more complete understanding of Ebola transmission dynamics. This paper conducts a meta-analysis of eight studies that measure seroprevalence (the number of subjects that test positive for anti-Ebolavirus antibodies in their blood) in subjects with household exposure or known case-contact with Ebola, but that have shown no symptoms. In our two random effects Bayesian hierarchical models, we find estimated seroprevalences of 8.76% and 9.72%, significantly higher than the 3.3% found by a previous meta-analysis of these eight studies. We also produce a variation of this meta-analysis where we exclude …

Constructing Phylogenetic Trees Using Maximum Likelihood, Anna Cho

Scripps Senior Theses

Maximum likelihood methods are used to estimate the phylogenetic trees for a set of species. The probabilities of DNA base substitutions are modeled by continuous-time Markov chains. We use these probabilities to estimate which DNA bases would produce the data that we observe. The topology of the tree is also determined using base substitution probabilities and conditional likelihoods. Felsenstein [2] introduced this method of finding an estimate for the maximum likelihood phylogenetic tree. We will explore this method in detail in this paper.

A Multistage Incidence Estimation Model For Diseases With Differential Mortality, Alyssa W. Dray

HMC Senior Theses

According to theWorld Health Organization, surgically removable cataract remains the leading cause of blindness worldwide. In sub-Saharan Africa, cataract surgical rate targets should ideally be set based on cataract incidence (the number of new cataracts developed each year). Unfortunately, the longitudinal studies necessary to measure incidence have not yet been feasible in these areas. Our research instead proposes a method for estimating incidence based on available cataract prevalence data. We extend a method proposed by Podgor and Leske (1986) to estimate age-specific incidence from age-specific prevalence in single diseases with differential mortality. A two-stage disease extension is created in order …