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Full-Text Articles in Physical Sciences and Mathematics

Studies Of N⁵, N¹⁰-Methylene Tetrahydrofolate Reductase From Porcine Kidney And Mouse L1210-Induced Tumor Tissues, Purification And Interaction With Antifolates, David W. Jayme Dec 1975

Studies Of N⁵, N¹⁰-Methylene Tetrahydrofolate Reductase From Porcine Kidney And Mouse L1210-Induced Tumor Tissues, Purification And Interaction With Antifolates, David W. Jayme

Theses and Dissertations

Methylene tetrahydrofolate reductase has been purified 1000-fold from porcine kidney and 400-fold from mouse L1210-induced tumor tissue by classical methods. The enzyme preparations have been demonstrated to be essentially free of contaminating methionine synthetase and serine transhydroxymethylase activity. Studies of the kinetic properties of the kidney and tumor enzymes, with respect to the reverse reaction using N5-methyl tetrahydrofolate as the variable substrate, have indicated Km values of 2.0 and 2.4 x 10-4 M, respectively. Inhibition of this key branch point enzyme in folate metabolism by a number of antimetabolites indicates that several of these antifolate compounds exhibit enzyme inhibition superior …


The Effect Of Recreational Uses On Vegetation And Soil In The Buffalo Campground, Targhee National Forest, Island Park, Idaho, Susan Daines Foster Aug 1975

The Effect Of Recreational Uses On Vegetation And Soil In The Buffalo Campground, Targhee National Forest, Island Park, Idaho, Susan Daines Foster

Theses and Dissertations

The effect of trampling on vegetation and soil, as a result of recreational pressure, was studied in the Buffalo campground of the Targhee National Forest, Idaho. Site deterioration was most evident in the forty-two year old site. The tree stand had matured, but there were few young trees and tree reproduction had been reduced to ten seedlings per acre for Pinus contorta. Only two shrub species were sampled with a combined population of eight individuals per acre. Most of the grass species had been seeded; forbs provided 20% of the ground cover, 13% was bare ground and 71% litter. The …


Close Coupling Test Of Classical And Semiclassical Cross Sections For Rotationally Inelastic Ar-N2 Collisions, Russell T. Pack Apr 1975

Close Coupling Test Of Classical And Semiclassical Cross Sections For Rotationally Inelastic Ar-N2 Collisions, Russell T. Pack

Faculty Publications

Accurate quantum mechanical close coupling (CC) integral cross sections are reported for rotationally inelastic Ar-N2 collisions at room temperature using an empirical intermolecular potential. These cross sections are used to test the infinite order sudden (IOS) approximation and the results of several methods [classical trajectories (CT), full sudden (SA), generalized phase shift (GPS), and classical limit generalized phase shift (CGPS)] as reported in the preceding paper by Pattengill. The IOS approximation works very well for cross sections involving low rotational states. The CT method works well for all the cross sections examined, justifying the popular belief that the rotational motion …


Use Of Selected Macroinvertebrates As Indicators Of Sedimentation Effects On Huntington River, Utah, Michael Kenneth Reichert Mar 1975

Use Of Selected Macroinvertebrates As Indicators Of Sedimentation Effects On Huntington River, Utah, Michael Kenneth Reichert

Theses and Dissertations

Benthic macroinvertebrate communities of Huntington River, Emery County, Utah were studied to determine effects of sedimentation from construction of Electric Lake Dam, a state highway, and two bridges. Approximately 900 benthic samples were collected from riffle areas above, in, and below the construction zone from January, 1971 to December, 1973. Two settling basins below construction sites were effective in limiting scouring of downstream communities. Heavy silt deposition was limited to a 1-km stream reach. Number of indicators, density, and biomass were reduced in the construction zone during periods of sediment input. During periods of scouring, density and biomass were reduced; …