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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Multiple Imputation Of Missing Data In Structural Equation Models With Mediators And Moderators Using Gradient Boosted Machine Learning, Robert J. Milletich Ii Oct 2016

Multiple Imputation Of Missing Data In Structural Equation Models With Mediators And Moderators Using Gradient Boosted Machine Learning, Robert J. Milletich Ii

Psychology Theses & Dissertations

Mediation and moderated mediation models are two commonly used models for indirect effects analysis. In practice, missing data is a pervasive problem in structural equation modeling with psychological data. Multiple imputation (MI) is one method used to estimate model parameters in the presence of missing data, while accounting for uncertainty due to the missing data. Unfortunately, commonly used MI methods are not equipped to handle categorical variables or nonlinear variables such as interactions. In this study, we introduce a general MI framework that uses the Bayesian bootstrap (BB) method to generate posterior inferences for indirect effects and gradient boosted machine …


Machine Learning Methods For Medical And Biological Image Computing, Rongjian Li Jul 2016

Machine Learning Methods For Medical And Biological Image Computing, Rongjian Li

Computer Science Theses & Dissertations

Medical and biological imaging technologies provide valuable visualization information of structure and function for an organ from the level of individual molecules to the whole object. Brain is the most complex organ in body, and it increasingly attracts intense research attentions with the rapid development of medical and bio-logical imaging technologies. A massive amount of high-dimensional brain imaging data being generated makes the design of computational methods for efficient analysis on those images highly demanded. The current study of computational methods using hand-crafted features does not scale with the increasing number of brain images, hindering the pace of scientific discoveries …


Machine Learning Methods For Brain Image Analysis, Ahmed Fakhry Jul 2016

Machine Learning Methods For Brain Image Analysis, Ahmed Fakhry

Computer Science Theses & Dissertations

Understanding how the brain functions and quantifying compound interactions between complex synaptic networks inside the brain remain some of the most challenging problems in neuroscience. Lack or abundance of data, shortage of manpower along with heterogeneity of data following from various species all served as an added complexity to the already perplexing problem. The ability to process vast amount of brain data need to be performed automatically, yet with an accuracy close to manual human-level performance. These automated methods essentially need to generalize well to be able to accommodate data from different species. Also, novel approaches and techniques are becoming …