Physical Sciences and Mathematics Commons^™

A Comparison Of Microarray Analyses: A Mixed Models Approach Versus The Significance Analysis Of Microarrays, Nathan Wallace Stephens

Theses and Dissertations

DNA microarrays are a relatively new technology for assessing the expression levels of thousands of genes simultaneously. Researchers hope to find genes that are differentially expressed by hybridizing cDNA from known treatment sources with various genes spotted on the microarrays. The large number of tests involved in analyzing microarrays has raised new questions in multiple testing. Several approaches for identifying differentially expressed genes have been proposed. This paper considers two: (1) a mixed models approach, and (2) the Signiffcance Analysis of Microarrays.

Dynamic Modeling And Statistical Analysis Of Event Times, Edsel A. Pena

Faculty Publications

This review article provides an overview of recent work in the modeling and analysis of recurrent events arising in engineering, reliability, public health, biomedicine and other areas. Recurrent event modeling possesses unique facets making it different and more difficult to handle than single event settings. For instance, the impact of an increasing number of event occurrences needs to be taken into account, the effects of covariates should be considered, potential association among the interevent times within a unit cannot be ignored, and the effects of performed interventions after each event occurrence need to be factored in. A recent general class …

A Logistic Regression Analysis Of Utah Colleges Exit Poll Response Rates Using Sas Software, Clint W. Stevenson

Theses and Dissertations

In this study I examine voter response at an interview level using a dataset of 7562 voter contacts (including responses and nonresponses) in the 2004 Utah Colleges Exit Poll. In 2004, 4908 of the 7562 voters approached responded to the exit poll for an overall response rate of 65 percent. Logistic regression is used to estimate factors that contribute to a success or failure of each interview attempt. This logistic regression model uses interviewer characteristics, voter characteristics (both respondents and nonrespondents), and exogenous factors as independent variables. Voter characteristics such as race, gender, and age are strongly associated with response. …

Student Fact Book, Fall 2006, Twenty-Ninth Annual Edition, Wright State University, Office Of Student Information Systems, Wright State University

Wright State University Student Fact Books

The student fact book has general demographic information on all students enrolled at Wright State University for Fall Quarter, 2006.

Multiattribute Acceptance Sampling Plans., Anup Majumdar Dr.

Doctoral Theses

Irrespective of the type of product, evaluation of conformity to specified requirements of its quality characteristics is an integral part of quality assurance. Although they form a set of necessary verification activities almost at all stages of production, these activities, known as inspection do not add value to the product on their own and are to be kept at their minimum. The sampling inspection where a portion of a collection of product units is inspected on a set of characteristics with a view to making decision about acceptance or otherwise becomes relevant in this context.The number of elements of the …

Theory Of Effectiveness Measurement, Richard K. Bullock

Theses and Dissertations

Effectiveness measures provide decision makers feedback on the impact of deliberate actions and affect critical issues such as allocation of scarce resources, as well as whether to maintain or change existing strategy. Currently, however, there is no formal foundation for formulating effectiveness measures. This research presents a new framework for effectiveness measurement from both a theoretical and practical view. First, accepted effects-based principles, as well as fundamental measurement concepts are combined into a general, domain independent, effectiveness measurement methodology. This is accomplished by defining effectiveness measurement as the difference, or conceptual distance from a given system state to some reference …

Bayesian And Positive Matrix Factorization Approaches To Pollution Source Apportionment, Jeff William Lingwall

Theses and Dissertations

The use of Positive Matrix Factorization (PMF) in pollution source apportionment (PSA) is examined and illustrated. A study of its settings is conducted in order to optimize them in the context of PSA. The use of a priori information in PMF is examined, in the form of target factor profiles and pulling profile elements to zero. A Bayesian model using lognormal prior distributions for source profiles and source contributions is fit and examined.

Abstracts Of Papers, 84th Annual Meeting Of The Virginia Academy Of Science

Virginia Journal of Science

Full abstracts of papers for the 84th Annual Meeting of the Virginia Academy of Science, May 25-26, 2006, Virginia Polytechnic Institute and State University, Blacksburg, VA

Modeling And Simulation Of Value -At -Risk In The Financial Market Area, Xiangyin Zheng

Doctoral Dissertations

Value-at-Risk (VaR) is a statistical approach to measure market risk. It is widely used by banks, securities firms, commodity and energy merchants, and other trading organizations. The main focus of this research is measuring and analyzing market risk by modeling and simulation of Value-at-Risk for portfolios in the financial market area. The objectives are (1) predicting possible future loss for a financial portfolio from VaR measurement, and (2) identifying how the distributions of the risk factors affect the distribution of the portfolio. Results from (1) and (2) provide valuable information for portfolio optimization and risk management.

The model systems chosen …

Modeling And Characterizations Of New Notions In Life Testing With Statistical Applications, Mohammad Sepehrifar

Electronic Theses and Dissertations

Knowing the class to which a life distribution belongs gives us an idea about the aging of the device or system the life distribution represents, and enables us to compare the aging properties of different systems. This research intends to establish several new nonparametric classes of life distributions defined by the concept of inactivity time of a unit with a guaranteed minimum life length. These classes play an important role in the study of reliability theory, survival analysis, maintenance policies, economics, actuarial sciences and many other applied areas.

Analyzing Dna Microarrays With Undergraduate Statisticians, Johanna S. Hardin, Laura Hoopes, Ryan Murphy '06

Pomona Faculty Publications and Research

With advances in technology, biologists have been saddled with high dimensional data that need modern statistical methodology for analysis. DNA microarrays are able to simultaneously measure thousands of genes (and the activity of those genes) in a single sample. Biologists use microarrays to trace connections between pathways or to identify all genes that respond to a signal. The statistical tools we usually teach our undergraduates are inadequate for analyzing thousands of measurements on tens of samples. The project materials include readings on microarrays as well as computer lab activities. The topics covered include image analysis, filtering and normalization techniques, and …