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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Machine Learning Classification Of Primary Tissue Origin Of Cancer From Dna Methylation Markers, Sravani Gannavarapu Surya Naga
Machine Learning Classification Of Primary Tissue Origin Of Cancer From Dna Methylation Markers, Sravani Gannavarapu Surya Naga
UNLV Theses, Dissertations, Professional Papers, and Capstones
Cancer is one of the leading causes of death globally and was responsible for approximately 9.6 million deaths in 2018. One of the main reason for deaths from cancer is late-stage presentation and inaccessible diagnosis and treatment. Cancer often spreads from the part of the body where it started (primary site) to a different part of the body (metastatic site). Identifying the primary site of cancer plays a key role as it directs the appropriate treatment. Cancer which spreads needs the same treatment as its origin. Having this knowledge can help doctors to decide the type of treatment.
All cancers …
Application Of Machine Learning In Cancer Research, Mandana Bozorgi
Application Of Machine Learning In Cancer Research, Mandana Bozorgi
UNLV Theses, Dissertations, Professional Papers, and Capstones
This dissertation revisits the problem of five-year survivability predictions for breast cancer using machine learning tools. This work is distinguishable from the past experiments based on the size of the training data, the unbalanced distribution of data in minority and majority classes, and modified data cleaning procedures. These experiments are also based on the principles of TIDY data and reproducible research. In order to fine-tune the predictions, a set of experiments were run using naive Bayes, decision trees, and logistic regression.
Of particular interest were strategies to improve the recall level for the minority class, as the cost of misclassification …
The Role Of Pre-Existing Type 2 Diabetes Mellitus In Colorectal Cancer Stage And Survival In Elderly Americans: A Seer-Medicare Population-Based Study 2002-~2011, Sanae El Ibrahimi
The Role Of Pre-Existing Type 2 Diabetes Mellitus In Colorectal Cancer Stage And Survival In Elderly Americans: A Seer-Medicare Population-Based Study 2002-~2011, Sanae El Ibrahimi
UNLV Theses, Dissertations, Professional Papers, and Capstones
Diabetes is a common comorbid condition among colorectal cancer (CRC) patients, yet its effects in CRC outcomes, particularly stage at diagnosis, risk of death and variations by diabetes severity (complications vs no complications) and Hispanic ethnicity have not been adequately studied. The purpose of this study was to investigate the association between pre-existing T2DM and advanced stage at diagnosis in elderly patients with CRC; to examine whether diabetes is an independent predictor of poor survival from all-cause and CRC-specific mortality; to assess whether variations exist by diabetes severity and to analyze the outcomes for the Hispanic group.
The Surveillance Epidemiology …