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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Principal Component Analysis For Predicting Transcription-Factor Binding Motifs From Array-Derived Data, Yunlong Liu, Matthew P Vincenti, Hiroki Yokota Nov 2005

Principal Component Analysis For Predicting Transcription-Factor Binding Motifs From Array-Derived Data, Yunlong Liu, Matthew P Vincenti, Hiroki Yokota

Dartmouth Scholarship

The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to transcription-factor binding motifs (TFBMs). In order to select a critical set of TFBMs from genomic DNA information and an array-derived data, an efficient algorithm to solve a combinatorial optimization problem is required. Although computational approaches based on evolutionary algorithms are commonly employed, an analytical algorithm would be useful to predict TFBMs at nearly no computational cost and evaluate varying modelling conditions. Singular value decomposition (SVD) is a powerful method to derive primary components of a given matrix. Applying SVD …


Model Simulations Of A Shock‐Cloud Interaction In The Cygnus Loop, Daniel J. Patnaude, Robert A. Fesen Jul 2005

Model Simulations Of A Shock‐Cloud Interaction In The Cygnus Loop, Daniel J. Patnaude, Robert A. Fesen

Dartmouth Scholarship

We present optical observations and two-dimensional hydrodynamic modeling of an isolated shocked ISM cloud. Hα images taken in 1992.6 and 2003.7 of a small optical emission cloud along the southwestern limb of the Cygnus Loop were used to measure positional displacements of ~01 yr-1 for surrounding Balmer-dominated emission filaments and 0025-0055 yr-1 for internal cloud emission features. These measurements imply transverse velocities of 250 and 80-140 km s-1 for ambient ISM and internal cloud shocks, respectively. A lack of observed turbulent gas stripping at the cloud-ISM boundary in the Hα images suggests that there is not an …


The Oxford-Dartmouth Thirty Degree Survey - Ii. Clustering Of Bright Lyman Break Galaxies: Strong Luminosity-Dependent Bias At Z = 4, Paul D. Allen, Leonidas A. Moustakas, Gavin Dalton, Emily Macdonald, Chris Blake, Lee Clewley, Catherine Heymans, Gary Wegner Apr 2005

The Oxford-Dartmouth Thirty Degree Survey - Ii. Clustering Of Bright Lyman Break Galaxies: Strong Luminosity-Dependent Bias At Z = 4, Paul D. Allen, Leonidas A. Moustakas, Gavin Dalton, Emily Macdonald, Chris Blake, Lee Clewley, Catherine Heymans, Gary Wegner

Dartmouth Scholarship

We present measurements of the clustering properties of bright (L > L*) z~4 Lyman break galaxies (LBGs) selected from the Oxford-Dartmouth Thirty Degree Survey (ODT). We describe techniques used to select and evaluate our candidates and calculate the angular correlation function, which we find best fitted by a power law, ω(θ) =Awθ−β with Aw= 15.4 (with θ in arcsec), using a constrained slope of β= 0.8. Using a redshift distribution consistent with photometric models, we deproject this correlation function and find a comoving Mpc in a Ωm= 0.3 flat λ cosmology for iAB≤ 24.5. This corresponds to a linear bias value …