Physical Sciences and Mathematics Commons^™

Deep Learning For Skin Photoaging, Gokul Srinivasan

Computer Science Senior Theses

Skin photoaging is the premature aging of skin that results from ultraviolet light exposure. It is a major risk factor for the development of skin cancer, among other malignant skin pathologies. Accordingly, understanding its etiology is important for both preventative and reparative clinical action. In this study, skin samples obtained from patients with ranging solar elastosis grades – a proxy for skin photoaging – were sequenced using next-generation sequencing techniques to further understand the genomic, epigenomic, and histological signs and signals of skin photoaging. The results of this study suggest that tissues with severe photoaging exhibit increases in the frequency …