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Full-Text Articles in Physical Sciences and Mathematics

Chromatin Pattern Quantification For The Differentiation Of White Blood Cells, Paul Young, Ryan Cordner, Abigail Gordhamer Feb 2024

Chromatin Pattern Quantification For The Differentiation Of White Blood Cells, Paul Young, Ryan Cordner, Abigail Gordhamer

Annual Research Symposium

Nuclear chromatin patterns have been used historically to distinguish between different developmental stages and lineages of white blood cells. While it is common to characterize cells based on arbitrary ‘open’ or ‘closed’ chromatin patterns, quantification of chromatin data is lacking. By extracting nuclei from a database of white blood cells and running fractal analyses using TWOMBLI, we were able to produce meaningful data quantifying chromatin patterns. Our data were put through a random forest algorithm which grouped each point based on relationship probability. The algorithm compared immature and mature cell types as well as cells of similar maturity and differing …


Requiring Students To Integrate Chatgptinto Course Assignments, Mark Small, Venera Balidemaj Jan 2024

Requiring Students To Integrate Chatgptinto Course Assignments, Mark Small, Venera Balidemaj

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.