Physical Sciences and Mathematics Commons^™

Dynamic Neuromechanical Sets For Locomotion, Aravind Sundararajan

Doctoral Dissertations

Most biological systems employ multiple redundant actuators, which is a complicated problem of controls and analysis. Unless assumptions about how the brain and body work together, and assumptions about how the body prioritizes tasks are applied, it is not possible to find the actuator controls. The purpose of this research is to develop computational tools for the analysis of arbitrary musculoskeletal models that employ redundant actuators. Instead of relying primarily on optimization frameworks and numerical methods or task prioritization schemes used typically in biomechanics to find a singular solution for actuator controls, tools for feasible sets analysis are instead developed …

Application Of Crowdsourced Data In Transportation Operations And Safety, Nima Hoseinzadeh

Doctoral Dissertations

Crowdsourcing refers to the acquisition of data from users who contribute their information via smartphone, social media, or the internet. In transportation systems, crowdsourcing turns users into real-time sensors, providing data on traffic speed, travel time, mile traveled, incidents, roadway conditions, weather severity, irregularities in traffic patterns, and hazards. These data can be collected actively or passively in quantitative or qualitative forms. With the emergence of smartphones and navigation apps, crowdsourced data are gaining increased attention in transportation. Crowdsourced data have advantages over traditional fixed-location sensors and camera monitoring: low implementation costs, extended geographic coverage, high resolution, real-time application, increased …

Nonparametric Bayesian Deep Learning For Scientific Data Analysis, Devanshu Agrawal

Doctoral Dissertations

Deep learning (DL) has emerged as the leading paradigm for predictive modeling in a variety of domains, especially those involving large volumes of high-dimensional spatio-temporal data such as images and text. With the rise of big data in scientific and engineering problems, there is now considerable interest in the research and development of DL for scientific applications. The scientific domain, however, poses unique challenges for DL, including special emphasis on interpretability and robustness. In particular, a priority of the Department of Energy (DOE) is the research and development of probabilistic ML methods that are robust to overfitting and offer reliable …

Root Stage Distributions And Their Importance In Plant-Soil Feedback Models, Tyler Poppenwimer

Doctoral Dissertations

Roots are fundamental to PSFs, being a key mediator of these feedbacks by interacting with and affecting the soil environment and soil microbial communities. However, most PSF models aggregate roots into a homogeneous component or only implicitly simulate roots via functions. Roots are not homogeneous and root traits (nutrient and water uptake, turnover rate, respiration rate, mycorrhizal colonization, etc.) vary with age, branch order, and diameter. Trait differences among a plant’s roots lead to variation in root function and roots can be disaggregated according to their function. The impact on plant growth and resource cycling of changes in the distribution …

Bayesian Topological Machine Learning, Christopher A. Oballe

Doctoral Dissertations

Topological data analysis encompasses a broad set of ideas and techniques that address 1) how to rigorously define and summarize the shape of data, and 2) use these constructs for inference. This dissertation addresses the second problem by developing new inferential tools for topological data analysis and applying them to solve real-world data problems. First, a Bayesian framework to approximate probability distributions of persistence diagrams is established. The key insight underpinning this framework is that persistence diagrams may be viewed as Poisson point processes with prior intensities. With this assumption in hand, one may compute posterior intensities by adopting techniques …

Interacting Effects Of Climate And Biotic Factors On Mesocarnivore Distribution And Snowshoe Hare Demography Along The Boreal-Temperate Ecotone, Alexej P. Siren

Doctoral Dissertations

The motivation of my dissertation research was to understand the influence of climate and biotic factors on range limits with a focus on winter-adapted species, including the Canada lynx (Lynx canadensis), American marten (Martes americana), and snowshoe hare (Lepus americanus). I investigated range dynamics along the boreal-temperate ecotone of the northeastern US. Through an integrative literature review, I developed a theoretical framework building from existing thinking on range limits and ecological theory. I used this theory for my second chapter to evaluate direct and indirect causes of carnivore range limits in the northeastern US, …

Latent Class Models For At-Risk Populations, Shuaimin Kang

Doctoral Dissertations

Clustering Network Tree Data From Respondent-Driven Sampling With Application to Opioid Users in New York City There is great interest in finding meaningful subgroups of attributed network data. There are many available methods for clustering complete network. Unfortunately, much network data is collected through sampling, and therefore incomplete. Respondent-driven sampling (RDS) is a widely used method for sampling hard-to-reach human populations based on tracing links in the underlying unobserved social network. The resulting data therefore have tree structure representing a sub-sample of the network, along with many nodal attributes. In this paper, we introduce an approach to adjust mixture models …

The Limits Of Location Privacy In Mobile Devices, Keen Yuun Sung

Doctoral Dissertations

Mobile phones are widely adopted by users across the world today. However, the privacy implications of persistent connectivity are not well understood. This dissertation focuses on one important concern of mobile phone users: location privacy. I approach this problem from the perspective of three adversaries that users are exposed to via smartphone apps: the mobile advertiser, the app developer, and the cellular service provider. First, I quantify the proportion of mobile users who use location permissive apps and are able to be tracked through their advertising identifier, and demonstrate a mark and recapture attack that allows continued tracking of users …

Bayesian Methods For The Assessment Of Reporting Errors For Data-Sparse Population-Periods With Applications To Estimating Mortality, Emily Peterson

Doctoral Dissertations

Population level mortality data is often subject to substantial reporting errors due to misclassification of cause of death, misclassification of death status, or age reporting errors. Accuracy of error-prone data sources can be assessed by comparing such data to gold standard data for the same population-period. We present Bayesian methods for assessing the extent of reporting errors across different population-periods and generalizing those to settings where gold-standard data are lacking. Firstly, we investigate misclassification errors of maternal cause of death reporting in civil registration vital statistics data. We use a Bayesian hierarchical bivariate random-walk model to estimate country-year specific sensitivity …

Nanoindentation Characterization Of Elastic Properties Of Shales And Swelling Clay Minerals, Shengmin Luo

Doctoral Dissertations

Oil and gas shales are a class of multiscale, multiphase, hybrid inorganic-organic sedimentary rocks that consist of a generally uniform, preferentially oriented clay matrix with randomly embedded silt and sand particles as solid inclusions. A thorough understanding of the mechanical properties of shales is crucial for the exploration and production of oil and gas in the unconventional shale reservoirs, but it can be a challenging task due to their nature of compositional heterogeneity and microstructural anisotropy. In efforts to better characterize the mechanical properties of shales across different length scales and to fundamentally understand the laws of upscaling from individual …

Fuzzy Logistic Regression For Detecting Differential Dna Methylation Regions, Tarek M. Bubaker Bennaser

Doctoral Dissertations

“Epigenetics is the study of changes in gene activity or function that are not related to a change in the DNA sequence. DNA methylation is one of the main types of epigenetic modifications, that occur when a methyl chemical group attaches to a cytosine on the DNA sequence. Although the sequence does not change, the addition of a methyl group can change the way genes are expressed and produce different phenotypes. DNA methylation is involved in many biological processes and has important implications in the fields of biomedicine and agriculture.

Statistical methods have been developed to compare DNA methylation at …