Physical Sciences and Mathematics Commons^™

Uganda As A Role Model For Pandemic Containment In Africa, Ahmed M. Sarki, Alex Ezeh, Saverio Stranges

Epidemiology and Biostatistics Publications

No abstract provided.

Participatory Video As A Novel Recovery-Oriented Intervention In Early Psychosis: A Pilot Study., Arlene G Macdougall, Sahana Kukan, Elizabeth Price, Sarah Glen, Richelle Bird, Laura Powe, Joshua C. Wiener, Paul H Lysaker, Kelly K Anderson, Ross Mg Norman

Epidemiology and Biostatistics Publications

BACKGROUND: Personal narrative plays an important role in the process of recovery from psychotic illnesses. Participatory video is a novel, active intervention that can be used as a tool for fostering narrative development among people with psychosis.

AIM: To assess the feasibility, acceptability and potential clinical utility of participatory video as an innovative tool for promoting recovery in early psychosis.

METHODS: Ten outpatients of an early psychosis intervention programme were recruited to participate in 13 biweekly workshops to plan, film and produce documentary-style videos of their experiences. Feasibility was measured through recruitment and retention. Acceptability was measured through workshop attendance …

The Impact Of The Diabetes Management Incentive On Diabetes-Related Services: Evidence From Ontario, Canada., Thaksha Thavam, Rose Anne Devlin, Amardeep Thind, Gregory S Zaric, Sisira Sarma

Epidemiology and Biostatistics Publications

Financial incentives have been introduced in several countries to improve diabetes management. In Ontario, the most populous province in Canada, a Diabetes Management Incentive (DMI) was introduced to family physicians practicing in patient enrollment models in 2006. This paper examines the impact of the DMI on diabetes-related services provided to individuals with diabetes in Ontario. Longitudinal health administrative data were obtained for adults diagnosed with diabetes and their family physicians. The study population consisted of two groups: DMI group (patients enrolled with a family physician exposed to DMI for 3 years), and comparison group (patients affiliated with a family physician …

Statistical Methods With A Focus On Joint Outcome Modeling And On Methods For Fire Science, Da Zhong Xi

Electronic Thesis and Dissertation Repository

Understanding the dynamics of wildfires contributes significantly to the development of fire science. Challenges in the analysis of historical fire data include defining fire dynamics within existing statistical frameworks, modeling the duration and size of fires as joint outcomes, identifying the how fires are grouped into clusters of subpopulations, and assessing the effect of environmental variables in different modeling frameworks. We develop novel statistical methods to consider outcomes related to fire science jointly. These methods address these challenges by linking univariate models for separate outcomes through shared random effects, an approach referred to as joint modeling. Comparisons with existing …

Stirring The Pot: Switching From Blended Fee-For-Service To Blended Capitation Models Of Physician Remuneration., Nibene H Somé, Rose Anne Devlin, Nirav Mehta, Gregory S Zaric, Sisira Sarma

Epidemiology and Biostatistics Publications

In Canada's most populous province, Ontario, family physicians may choose between the blended fee-for-service (Family Health Group [FHG]) and blended capitation (Family Health Organization [FHO] payment models). Both models incentivize physicians to provide after-hours (AH) and comprehensive care, but FHO physicians receive a capitation payment per enrolled patient adjusted for age and sex, plus a reduced fee-for-service while FHG physicians are paid by fee-for-service. We develop a theoretical model of physician labor supply with multitasking to predict their behavior under FHG and FHO, and estimable equations are derived to test the predictions empirically. Using health administrative data from 2006 to …

Call To Action: Sars-Cov-2 And Cerebrovascular Disorders (Cascade), Shahram Abootalebi, Benjamin M. Aertker, Mohammad Sobhan Andalibi, Negar Asdaghi, Ozlem Aykac, M. Reza Azarpazhooh, M. Cecilia Bahit, Kristian Barlinn, Hamidon Basri, Reza Bavarsad Shahripour, Anna Bersano, Jose Biller, Afshin Borhani-Haghighi, Robert D. Brown, Bruce Cv Campbell, Salvador Cruz-Flores, Deidre Anne De Silva, Mario Di Napoli, Afshin A. Divani, Randall C. Edgell, Johanna T. Fifi, Abdoreza Ghoreishi, Teruyuki Hirano, Keun Sik Hong, Chung Y. Hsu, Josephine F. Huang, Manabu Inoue, Amanda L. Jagolino, Moira Kapral, Hoo Fan Kee, Zafer Keser, Rakesh Khatri

Epidemiology and Biostatistics Publications

Background and purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), now named coronavirus disease 2019 (COVID-19), may change the risk of stroke through an enhanced systemic inflammatory response, hypercoagulable state, and endothelial damage in the cerebrovascular system. Moreover, due to the current pandemic, some countries have prioritized health resources towards COVID-19 management, making it more challenging to appropriately care for other potentially disabling and fatal diseases such as stroke. The aim of this study is to identify and describe changes in stroke epidemiological trends before, during, and after the COVID-19 pandemic. Methods: This is an international, multicenter, hospital-based …

A Treatise Of Pd-Lgd Correlation Modelling, Wisdom S. Avusuglo Wsa

Electronic Thesis and Dissertation Repository

The provision in Paragraph 468 of Basel II Framework Document for calculating loss given default (LGD) requires that parameters used in Pillar I of Basel II capital estimations must be reflective of economic downturn conditions so that relevant risks are accounted for. This provision is based on the fact that the probability of default (PD) and LGD correlations are not captured in the proposed formula for estimating economic capital. To help quantify economic downturn LGD, the Basel Committee proposed establishing a functional relationship between long-run and downturn LGD.

To the best of our knowledge, the current proposed models that map …

Ranking Comments: An Entropy-Based Method With Word Embedding Clustering, Yuyang Zhang

Electronic Thesis and Dissertation Repository

Automatically ranking comments by their relevance plays an important role in text mining and text summarization area. In this thesis, firstly, we introduce a new text digitalization method: the bag of word clusters model. Unlike the traditional bag of words model that treats each word as an independent item, we group semantic-related words as clusters using pre-trained word2vec word embeddings and represent each comment as a distribution of word clusters. This method can extract both semantic and statistical information from texts. Next, we propose an unsupervised ranking algorithm that identifies relevant comments by their distance to the “ideal” comment. The …

Renewable-Energy Resources, Economic Growth And Their Causal Link, Yiyang Chen

Electronic Thesis and Dissertation Repository

This thesis examines the presence and strength of predictive causal relationship between re-newable energy prices and economic growth. We look for evidence by investigating the cases of Norway, New Zealand, and Canada’s two provinces of Alberta and Ontario. The usual vectorautoregressive model (VAR) and its various improved versions still assume constant parametersover time. We devise a Markov-switching VAR (MS-VAR) model in order to accommodate the observed time-dependent causal relation changes. Our proposed modelling approach is induced by the hidden Markov model methodologies in terms of an online parameter estimationthrough recursive filtering. The parameters of the MS-VAR model are governed by …

Classification-Based Method For Estimating Dynamic Treatment Regimes, Junwei Shen

Electronic Thesis and Dissertation Repository

Dynamic treatment regimes are sequential decision rules dictating how to individualize treatments to patients based on evolving treatments and covariate history. In this thesis, we investigate two methods of estimating dynamic treatment regimes. The first method extends outcome weighted learning from two-treatments to multi-treatments and allows for negative treatment outcome. We show that under two different sets of assumptions, the Fisher consistency can be maintained. The second method estimates treatment rules by a neural classification tree. A weighted squared loss function is defined to approximate the indicator function to maintain the smoothness. A method of tree reconstruction and pruning is …

Risk Of New Bloodstream Infections And Mortality Among People Who Inject Drugs With Infective Endocarditis., Charlie Tan, Esfandiar Shojaei, Joshua C. Wiener, Meera Shah, Sharon Koivu, Michael Silverman

Epidemiology and Biostatistics Publications

IMPORTANCE: People who inject drugs (PWID) who are being treated for infective endocarditis remain at risk of new bloodstream infections (BSIs) due to ongoing intravenous drug use (IVDU).

OBJECTIVES: To characterize new BSIs in PWID receiving treatment for infective endocarditis, to determine the clinical factors associated with their development, and to determine whether new BSIs and treatment setting are associated with mortality.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study was performed at 3 tertiary care hospitals in London, Ontario, Canada, from April 1, 2007, to March 31, 2018. Participants included a consecutive sample of all PWID 18 years or …

The Impact Of Improved Access To After-Hours Primary Care On Emergency Department And Primary Care Utilization: A Systematic Review., Michael Hong, Amardeep Thind, Gregory S Zaric, Sisira Sarma

Epidemiology and Biostatistics Publications

Access to after-hours primary care is problematic in many developed countries, leading patients to instead visit the emergency department for non-urgent conditions. However, emergency department utilization for conditions treatable in primary care settings may contribute to emergency department overcrowding and increased health system costs. This systematic review examines the impact of various initiatives by developed countries to improve access to after-hours primary care on emergency department and primary care utilization. We performed a systematic review on the impact of improved access to after-hours primary and searched CINAHL, EMBASE, MEDLINE, and Scopus. We identified 20 studies that examined the impact of …

Extensions Of Classification Method Based On Quantiles, Yuanhao Lai

Electronic Thesis and Dissertation Repository

This thesis deals with the problem of classification in general, with a particular focus on heavy-tailed or skewed data. The classification problem is first formalized by statistical learning theory and several important classification methods are reviewed, where the distance-based classifiers, including the median-based classifier and the quantile-based classifier (QC), are especially useful for the heavy-tailed or skewed inputs. However, QC is limited by its model capacity and the issue of high-dimensional accumulated errors. Our objective of this study is to investigate more general methods while retaining the merits of QC.

We present four extensions of QC, which appear in chronological …

Generalized 4/2 Factor Model, Yuyang Cheng

Electronic Thesis and Dissertation Repository

We investigate portfolio optimization, risk management, and derivative pricing for a factor stochastic model that considers the 4/2 stochastic volatility on the common/systematic factor as well as on the intrinsic factor. This setting allows us to capture stochastic volatility and stochastic covariation among assets. The model is also a generalization of existing models in the literature as it includes the mean reverting property and spillover effect to capture wider types of financial assets. At a theoretical level we identify conditions for well-defined changes of measure. A quasi-closed form solution within a 4/2 structured model is obtained for a portfolio optimization …

Issues Related To Framing And Interpretation Of Studies In The Orthopaedic Literature, Shgufta Docter

Electronic Thesis and Dissertation Repository

In research, appropriate statistical interpretation and methodology are essential to conduct quality work. To interpret results, p-values are frequently used in isolation, but this is insufficient as treatment effects, confidence intervals (CIs), and clinically important thresholds should also be reported. Further, the equality, superiority, non-inferiority, and equivalence frameworks have critical differences not well delineated in current literature. We conducted a systematic review of studies published in high-impact orthopaedic journals and examined a) how well studies interpreted the results of patient-reported outcome measures, and b) whether a consistent framework was used throughout studies. We found that the majority of studies do …

Excess Mortality From Covid-19: A Commentary On The Italian Experience, Paolo Pasquariello, Saverio Stranges

Epidemiology and Biostatistics Publications

No abstract provided.

Edge-Cloud Iot Data Analytics: Intelligence At The Edge With Deep Learning, Ananda Mohon M. Ghosh

Electronic Thesis and Dissertation Repository

Rapid growth in numbers of connected devices, including sensors, mobile, wearable, and other Internet of Things (IoT) devices, is creating an explosion of data that are moving across the network. To carry out machine learning (ML), IoT data are typically transferred to the cloud or another centralized system for storage and processing; however, this causes latencies and increases network traffic. Edge computing has the potential to remedy those issues by moving computation closer to the network edge and data sources. On the other hand, edge computing is limited in terms of computational power and thus is not well suited for …

Age At Migration And The Risk Of Psychotic Disorders: A Systematic Review And Meta-Analysis., Kelly K. Anderson, Jordan Edwards

Epidemiology and Biostatistics Publications

OBJECTIVE: To conduct a systematic review and meta-analysis of the existing evidence on the association between age at migration and the risk of psychotic disorders.

METHODS: Observational studies were eligible for inclusion if they presented data on the association between age at migration and the risk of psychotic disorders among first-generation migrant groups. We used two random effects meta-analyses to pool effect estimates for each stratum of age at migration relative to (i) a native-born reference category and (ii) the youngest age stratum (0 to 2 years).

RESULTS: Ten studies met inclusion criteria, and five were included in the meta-analysis. …

Rdc Data Alternatives: Conducting Research During Covid-19, Kristi Thompson, Elizabeth Hill

Western Libraries Presentations

Recent physical distancing protocols pertaining to the COVID-19 Pandemic have meant that RDC researchers need to find alternatives ways of carrying out their research. The Real Time Remote Access (RTRA) program offers one alternative way to access confidential Statistics Canada data. Other options include using the Statistics Canada public use files and analyzing data from other sources.

The presenters, data librarians from Western Libraries will discuss the differences between the data that can be accessed through the RTRA the RDC. RTRA data is a very useful option for some types of questions but also has some important limitations. We will …

Point Process Modelling Of Objects In The Star Formation Complexes Of The M33 Galaxy, Dayi Li

Electronic Thesis and Dissertation Repository

In this thesis, Gibbs point process (GPP) models are constructed to study the spatial distribution of objects in the star formation complexes of the M33 galaxy. The GPP models circumvent the limitations of the two-point correlation function employed in the current astronomy literature by naturally accounting for the inhomogeneous distribution of these objects. The spatial distribution of these objects serves as a sensitive probe in understanding the star formation process, which is crucial in understanding the formation of galaxies and the Universe. The objects under study include the CO filament structure, giant molecular clouds (GMCs) and young stellar cluster candidates …

A Visual Analytics System For Investigating Multimorbidity Using Supervised Machine Learning, Maede Sadat Nouri

Electronic Thesis and Dissertation Repository

Patterns of multimorbidity are complex and difficult to summarise using static visualization techniques like tables and charts. We present a visual analytics system with the goal of facilitating the process of making sense of data collected from patients with multimorbidity. The system reveals underlying patterns in the data visually and interactively, which enables users to easily assess both prevalence and correlation estimates of different chronic diseases among multimorbid patients with varying characteristics. To do so, the system uses count-based conditional probability, binary logistic regression, softmax regression and decision tree models to dynamically compute and visualize prevalence and correlation estimates for …

Concordance Between Health Administrative Data And Survey-Derived Diagnoses For Mood And Anxiety Disorders, J. Edwards, A. Thind, S. Stranges, M. Chiu, Kelly K. Anderson

Epidemiology and Biostatistics Publications

Objective: To assess whether estimates of survey structured interview diagnoses of mood and anxiety disorders were concordant with diagnoses of these disorders obtained from health administrative data.

Methods: All Ontario respondents to the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH) were linked to health administrative databases at ICES (formerly known as the Institute for Clinical Evaluative Sciences). Survey structured interview diagnoses were compared with health administrative data diagnoses obtained using a standardized algorithm. We used modified Poisson regression analyses to assess whether socio-demographic factors were associated with concordance between the two measures.

Results: Of the 4157 Ontarians included in our …

Visualization And Joint Analysis Of Monitored Multivariate Spatio-Temporal Data With Applications To Forest Fire Modelling And Sports Analytics, Devan Becker

Electronic Thesis and Dissertation Repository

This thesis develops and applies novel techniques for the study of complex data structures with applications to wildland fire analytics and sports analytics. We consider situations where different models share information, including many different variables recorded simultaneously in aerial wildland fire fighting, how the frequency and severity of wildland fires are related, and how the shot locations of hockey players can be decomposed into spatial components that are shared across different players.

The first study analyzes flight patterns while fighting a wildland fire using several outlier detection techniques. These techniques applied several definitions of ``outlier'' to determine whether or not …

After-Hours Incentives And Emergency Department Visits: Evidence From Ontario Forthcoming At Canadian Public Policy, Rose Anne Devlin, Koffi Ahoto Kpelitse, Lihua Li, Nirav Mehta, Sisira Sarma

Epidemiology and Biostatistics Publications

No abstract provided.

Evaluating The Effectiveness Of Aquatic Therapy On Mobility, Balance, And Level Of Functional Independence In Stroke Rehabilitation: A Systematic Review And Meta-Analysis., Alice Mary Iliescu, Amanda Mcintyre, Joshua C. Wiener, Jerome Iruthayarajah, Andrea Lee, Sarah Caughlin, Robert Teasell

Epidemiology and Biostatistics Publications

OBJECTIVE: To meta-analyze and systematically review the effectiveness of aquatic therapy in improving mobility, balance, and functional independence after stroke.

DATA SOURCES: Articles published in Medline, Embase, CINAHL, PsycINFO, and Scopus up to 20 August 2019.

STUDY SELECTION: Studies met the following inclusion criteria: (1) English, (2) adult stroke population, (3) randomized or non-randomized prospectively controlled trial (RCT or PCT, respectively) study design, (4) the experimental group received >1 session of aquatic therapy, and (5) included a clinical outcome measure of mobility, balance, or functional independence.

DATA EXTRACTION: Participant characteristics, treatment protocols, between-group outcomes, point measures, and measures of variability …