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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Comparing Different Methods For Multiple Testing In Reaction Time Data, Massimiliano Pastore, Massimo Nucci, Giovanni Galfano
Comparing Different Methods For Multiple Testing In Reaction Time Data, Massimiliano Pastore, Massimo Nucci, Giovanni Galfano
Journal of Modern Applied Statistical Methods
Reaction times were simulated for examining the power of six methods for multiple testing, as a function of sample size and departures from normality. Power estimates were low for all methods for non-normal distributions. With normal distributions, even for small sample sizes, satisfactory power estimates were observed, especially for FDR-based procedures.
Statistical Issues In Efficacy Evaluation For Companion Animal Drug Development, Zhanglin Lin Cui, Wherly Hoffman
Statistical Issues In Efficacy Evaluation For Companion Animal Drug Development, Zhanglin Lin Cui, Wherly Hoffman
Conference on Applied Statistics in Agriculture
Companion animals, commonly called pets, are animals such as dogs, cats, and horses. The companion animal drug market has expanded rapidly in recent years. Two major points of focus in companion animal drug development are therapeutics and parasiticides. From a statistics point of view, experimental design, experimental unit determination, sample size estimation and reestimation, treatment design, data transformation, multiple testing, and proper modeling are major statistical issues when efficacy evaluation in a companion animal study is conducted. These major statistical issues are addressed using two clinical studies as examples: Reconcile® (Fluoxetine) for the treatment of separation anxiety in dogs and …