Physical Sciences and Mathematics Commons^™

Studying The Functional Genomics Of Stress Responses In Loblolly Pine With The Expresso Microarray Experiment Management System, Lenwood S. Heath, Naren Ramakrishnan, Ronald R. Sederoff, Ross W. Whetten, Boris I. Chevone, Craig Struble, Vincent Y. Jouenne, Dawei Chen, Leonel Van Zyl, Ruth Grene

Mathematics, Statistics and Computer Science Faculty Research and Publications

Conception, design, and implementation of cDNA microarray experiments present a variety of bioinformatics challenges for biologists and computational scientists. The multiple stages of data acquisition and analysis have motivated the design of Expresso, a system for microarray experiment management. Salient aspects of Expresso include support for clone replication and randomized placement; automatic gridding, extraction of expression data from each spot, and quality monitoring; flexible methods of combining data from individual spots into information about clones and functional categories; and the use of inductive logic programming for higher-level data analysis and mining. The development of Expresso is occurring in parallel with …