Physical Sciences and Mathematics Commons^™

Environmental And Genetic Factors Affecting Antibiotic Resistance Of Extended Spectrum Î?-Lactamase Bacteria From The Rio Grande River In El Paso, Tx And Cd. Juarez, Mexico, Maria D. Fuentes

Open Access Theses & Dissertations

Background: The Rio Grande River provides a major source of potable and agricultural water for the population of the Texas/Mexico border region. Cattle farming and ranching are the most prevalent activities, which may contribute to the microbial burden of pharmaceuticals into our state's water resources. Antibiotics, presumably released into the environment by discharges originating from waste-water treatment plants, septic disposal systems, animal feeding operations and urban runoff have a definite impact on the ecosystem and may contribute to an increase in antibiotic resistance. We hypothesized that waters of the Rio Grande River contained Multi Drug Resistant Organisms (MDRO) and mobile …

Utilizing Historical Mosquito Surveillance Data To Investigate The Efficacy Of Municipal Fogging In Controlling Mosquito Population Density, Andrea Betina Carzoli

Open Access Theses & Dissertations

Background: Mosquito borne diseases are the cause of many different disease syndromes and deaths in animals, both wild and domesticated, and humans of all ages and ethnicities. Though El Paso, TX is located in an arid region, mosquito populations are still rapidly growing in urban and agricultural communities and so are the mosquito borne illnesses. The most common vectors associated with mosquito borne illnesses in El Paso County are Culex quinquefasciatus, Culex tarsalis, and Aedes aegypti. Vector management is often the primary option to prevent and control outbreaks of mosquito borne illnesses and very often utilize fogging as the primary …

A Pilot Study Of Arsenic In Young Children From Two Rural West Texas Communities: Blood Levels, Household Water Levels, And Behavioral Outcomes, Michelle Del Rio

Open Access Theses & Dissertations

Background & Significance: Heavy metals have been identified as a child health hazard because children are highly vulnerable to the effects of exposure, which can be physical, cognitive, and behavioral. Levels of arsenic (As) greater than the EPA Maximum Contaminant Level (10μg/L) were identified in some household water samples in two rural west Texas communities located within 20 miles of the U.S.-Mexico border by a Health Impact Assessment conducted in 2013 (Hargrove, Juarez-Carillo, & Korc 2015). Whether home water samples predicted child blood As levels needed to be examined. Since lead (Pb) is another common heavy metal contaminant in the …

Functional Data Analysis To Guide A Conditional Likelihood Regression In A Case-Crossover Study Investigating Whether Social Characteristics Modify The Health Effects Of Air Pollution, Juana Maribel Herrera Hernandez

Open Access Theses & Dissertations

In this study we are focused on exploring whether social characteristics modify the relationship between air pollution and hospitalizations due to asthma or chronic pulmonary obstructive disease (COPD) in El Paso, Tx. The case-crossover design with conditional regression analysis was used, here the controls and the case are the same subject at different

times and has the advantage of removing confounding by permanently confounding factors. Social characteristics are included in the models as interactions with the pollutants, variables included are age, sex, ethnicity and insurance status as indicator for the socio-economic status. The pollutant's lags were chosen using the historical …

Disparities In Park Availability, Features, And Characteristics By Social Determinants Of Health Within A U.S.-Mexico Border Urban Area, Amir Kamel

Open Access Theses & Dissertations

Background: Parks have been shown to be a key feature in the built environment that promote physical activity and positively influence health. However, a number of studies have highlighted that park availability, park features (e.g., park facilities, amenities, and aesthetic features), and park characteristics (e.g., quality/safety concerns of the park and surrounding neighborhood) are not equally distributed across neighborhoods in the U.S, specifically areas of low socioeconomic status and diverse racial/ethnic composition. The overall aim of this study was to examine and describe park availability, park features, and park characteristics, and determine their association with two social determinants of health …

Application Of The Water Poverty Index In Border Colonias Of West Texas, Marcelo Korc

Open Access Theses & Dissertations

This study applied the Water Poverty Index (WPI) in border colonias and other rural areas of west Texas. The colonias are mostly unincorporated communities located primarily in New Mexico and Texas along the border with Mexico and are characterized by high poverty rates and substandard living conditions. In Texas, access to drinking water and sanitation services has been identified as one of the most significant determinants of health in over 350 colonias with about 50 thousand residents.

The WPI is a multidimensional measure that links household welfare with water availability. WPI components were identified and prioritized by a wide range …

Assessment Of Intra-Urban Traffic-Related Air Pollution On Asthmatic Children's Exposure At Schools In The Paso Del Norte Region, Amit Ugamraj Raysoni

Open Access Theses & Dissertations

Traffic-related air pollution can be a major public health concern in any urban area. This problem is compounded in the Paso del Norte region that has experienced rapid economic growth, and a substantial number of people living in close vicinity of major roadways. The desert surroundings, arid weather, frequent temperature inversions, heavy border traffic at the international ports of entry between El Paso and Ciudad Juárez, and poorly maintained vehicle fleet further exacerbates this problem. A growing body of air quality and epidemiologic research has discerned the linkage between traffic emissions and respiratory disorders.

Initial health investigations in the Paso …

Optimal Control Applied To A Discrete Time Influenza Model, Paula Andrea Gonzalez Parra

Open Access Theses & Dissertations

For the last decades, mathematical epidemiological models have been used to understand the dynamics of infectious diseases and guide public health policy.

In particular, several continuous models have been considered to study influenza outbreaks and their controls policies. However, most epidemiological data is discrete; therefore, a discrete formulation is more convenient to compare collected data with the output of the model. We introduce a discrete time model in order to study optimal control strategies for influenza transmission.

In our model, we divide the population into four classes: susceptible, infectious, treated, and recovered individuals.

In particular, we evaluate the potential effect …

Identifying Influential Observations Through The Intraclass Correlation Coefficient, Angel De Jesus Davalos

Open Access Theses & Dissertations

In this thesis, we analyze the performance of adapting the DFBETA statistic for identifying influential observations on the intraclass correlation coefficient under the assumptions of the one-way random effects model. Additionally, we introduce an approach for transforming negative intraclass correlation coefficient estimation values using the method of moments estimator. We apply this method on a data set of repeated blood pressure measurements, after which we will investigate implications of identifying influential observations.

In-Vivo Delivery Of Dna Vaccines Using Metallo-Lipid Nanoparticles, Clarissa Sara Gomez

Open Access Theses & Dissertations

There has been a rapidly growing area of research in the design and synthesis of molecules that self-organize in water to form functional nanosystems and due to the high interest in the area metal ligand complexes were tested as drug delivery systems with a Leishmania vaccine. Herein, we present the design, synthesis and functional activity of Cu(II) and Zn(II) complexes that self-assemble in water to form spherical nanoscale structures that exhibit an affinity to bind DNA and deliver it into eukaryotic cells with a high percent efficiency in-vitro. In order to assess the effectiveness of these nanoparticles to deliver DNA …