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Synthesis And Characterization Of Biodegradable Polyurethanes For Biomedical Application, Changhong Zhang

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This dissertation constitutes the studies about the biomedical materials research of novel polyurethanes. These elastic and degradable polyurethanes exhibited the potential for drug delivery, scaffold fabrication by novel ink-jet printing technology or other biomedical applications. This dissertation includes two parts about two different types of polyurethanes.
In the first part of this dissertation, we studied a polyurethane that was synthesized from methylene di-p-phenyl-diisocyanate (MDI), polycaprolactone diol (PCL-diol) and N, N-bis (2-hydorxyethyl)-2-aminoethane-sulfonic acid (BES). MDI, PCL-diol and BES were polymerized into polyurethane and served as the hard segment, soft segment and chain extender respectively. The effects of the chain extender BES …