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Forensic Significance Of Teal Colored Cashmere And Black Acrylic Fibers, Nicole M. Martin Jul 2015

Forensic Significance Of Teal Colored Cashmere And Black Acrylic Fibers, Nicole M. Martin

Nicole M Martin

Forensic Significance of Teal Colored Cashmere and Black Acrylic Fibers Textile fibers are a valuable type of trace evidence within forensic cases. They have the ability to connect a perpetrator to a victim and or a crime scene. Some types of fibers are more prevalent than others. The purpose of this research was to conduct a target fiber study in order to determine the significance of the selected fibers in a forensic case. Two fibers were selected from two different garments, black acrylic fiber and a teal colored cashmere fiber. Unknown fibers were collected from three local clothing stores and …


Hyaluronic Acid Based Self-Assembling Nanosystems For Cd44 Target Mediated Sirna Delivery To Solid Tumors., Arun Iyer Dec 2012

Hyaluronic Acid Based Self-Assembling Nanosystems For Cd44 Target Mediated Sirna Delivery To Solid Tumors., Arun Iyer

Arun Iyer

Anticancer therapeutics employing RNA interference mechanism holds promising potentials for sequence-specific silencing of target genes. However targeted delivery of siRNAs to tumor tissues and cells and more importantly, their intracellular release at sites of interest still remains a major challenge that needs to be addressed before this technique could become a clinically viable option. In the current study, we have engineered and screened a series of CD44 targeting hyaluronic acid (HA) based self-assembling nanosystems for targeted siRNA delivery. The HA polymer was functionalized with lipids of varying carbon chain lengths/nitrogen content, as well as polyamines for assessing siRNA encapsulation. From …