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- Diamond (2)
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- Axially Swept Light Sheet Microscopy (ASLM) (1)
- Filamentation (1)
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Articles 1 - 5 of 5
Full-Text Articles in Physical Sciences and Mathematics
Volumetric Imaging Using The Pupil-Matched Remote Focusing Technique In Light-Sheet Microscopy, Sayed Hassan Dibaji Foroushani
Volumetric Imaging Using The Pupil-Matched Remote Focusing Technique In Light-Sheet Microscopy, Sayed Hassan Dibaji Foroushani
Optical Science and Engineering ETDs
ABSTRACT
The dissertation explores innovative techniques in light sheet microscopy, a pivotal tool in biomedical imaging, to enhance its speed, resolution, and efficiency in capturing dynamic biological processes. Light sheet microscopy allows for quick 3D imaging of biological specimens ranging from cells to organs with high spatiotemporal resolution, large field-of-view, and minimal damage, making it vital for in vivo imaging.
The first project introduces a novel optical concept designed to optimize Axially Swept Light Sheet Microscopy (ASLM). This technique is crucial for imaging specimens ranging from live cells to chemically cleared organs due to its versatility across different immersion media. …
Super-Resolution Microscopy With Color Centers In Diamond, Forrest A. Hubert
Super-Resolution Microscopy With Color Centers In Diamond, Forrest A. Hubert
Optical Science and Engineering ETDs
This dissertation explores the development and application of diamond color centers, specifically the silicon-vacancy (SiV) and nitrogen-vacancy (NV) centers, in super-resolution microscopy and magnetic imaging techniques. It demonstrates the potential of SiV centers as photostable fluorophores in stimulated emission depletion (STED) microscopy, with a resolution of approximately 90 nm. The research also presents a method for nanoscale magnetic microscopy using NV centers by combining charge state depletion (CSD) microscopy with optically detected magnetic resonance (ODMR) to image magnetic fields produced by 30 nm iron-oxide nanoparticles. The individual magnetic feature width reaches ~100 nm while resolving magnetic field patterns from nanoparticles …
High-Power Laser Cooling And Temperature-Dependent Fluorescence Studies Of Ytterbium Doped Silica, Brian Topper
High-Power Laser Cooling And Temperature-Dependent Fluorescence Studies Of Ytterbium Doped Silica, Brian Topper
Optical Science and Engineering ETDs
Experimental observation of optical refrigeration using ytterbium doped silica glass in recent years has created a new solution for heat mitigation in high-power laser systems, nonlinear fiber experiments, integrated photonics, and precision metrology. Current efforts of different groups focus on compositional optimization, fiber fabrication, and investigating how much silica can be cooled with a laser. At the start of this work, the best effort in laser cooling ytterbium doped silica saw cooling by 6 K from room temperature. This dissertation follows the experimental efforts that culminated in the increase of this initial record by one order of magnitude. Comprehensive spectroscopic …
Filaments And Their Application To Air Lasing, Spectroscopy, And Guided Discharge, Ali Rastegari
Filaments And Their Application To Air Lasing, Spectroscopy, And Guided Discharge, Ali Rastegari
Optical Science and Engineering ETDs
Laser filamentation is a fascinating phenomenon that occurs when an intense laser beam travels through transparent materials, in particular air. At sufficiently high power (TW in the near IR, GW in the UV), instead of spreading out like a regular laser beam, something remarkable happens: the laser beam becomes tightly focused, creating a thin and intense column of light called a laser filament. Laser filamentation is characterized by two main properties: (I) a high-intensity core that remains narrow over long distances beyond the Rayleigh range and (II) a low-density plasma channel within the core. In recent years, laser filamentation has …
Femtotesla Magnetometry And Nanoscale Imaging With Color Centers In Diamond, Yaser Silani
Femtotesla Magnetometry And Nanoscale Imaging With Color Centers In Diamond, Yaser Silani
Optical Science and Engineering ETDs
Intriguing photophysical properties of color centers in diamond make them ideal candidates for many applications from imaging and sensing to quantum networking. In the first part of this work, we have studied the silicon vacancy (SiV) centers in diamond for nanoscale imaging applications. We showed that these centers are promising fluorophores for Stimulated Emission Depletion (STED) microscopy, owing to their photostable, near-infrared emission and favorable photophysical properties. In the second part, we built a femtotesla Radio-Frequency (RF) magnetometer based on the diamond nitrogen vacancy (NV) centers and magnetic flux concentrators. We used this sensor to remotely detect Nuclear Quadrupole Resonance …