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Physical Sciences and Mathematics Commons

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Physics

LSU Doctoral Dissertations

2021

Motion mitigation

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Full-Text Articles in Physical Sciences and Mathematics

A Generalized, Modular Approach To Treating Moving Tumors With Ion Beams, Michelle Jennifer Lis Jun 2021

A Generalized, Modular Approach To Treating Moving Tumors With Ion Beams, Michelle Jennifer Lis

LSU Doctoral Dissertations

Despite advancements in cancer therapy, certain indications continue to have a poor prognosis, including cancers of the thorax. Existing methods for treating moving tumors with carbon ions have shown promise, but require technologically complex facilities and still have inherent limitations to mitigating tumor motion. The goal of this dissertation was to develop and test a safe, portable, and modular motion-synchronized dose delivery system (M-DDS) and its peripheral components as a framework for studying motion mitigation with ion beams.

We designed and integrated a motion-synchronized radiotherapy approach, called multi-phase 4D delivery (MP4D), as modular units of a clinical dose delivery system. …