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Full-Text Articles in Physical Sciences and Mathematics
Optimization Of Electrostatic Interactions In Protein-Protein Complexes, Kelly Brock, Kemper Talley, Kacey Coley, Petras Kundrotas, Emil Alexov
Optimization Of Electrostatic Interactions In Protein-Protein Complexes, Kelly Brock, Kemper Talley, Kacey Coley, Petras Kundrotas, Emil Alexov
Publications
In this article, we present a statistical analysis of the electrostatic properties of 298 protein-protein complexes and 356 domain-domain structures extracted from the previously developed database of protein complexes (ProtCom, http://www.ces.clemson.edu/compbio/protcom). For each structure in the dataset we calculated the total electrostatic energy of the binding and its two components, Coulombic and reaction field energy. It was found that in a vast majority of the cases (>90%), the total electrostatic component of the binding energy was unfavorable. At the same time, the Coulombic component of the binding energy was found to favor the complex formation while …
Optical Absorption, Depolarization, And Scatter Of Epitaxial Single-Crystal Chemical-Vapor-Deposited Diamond At 1.064 Μm, Giorgio Turri, Ying Chen, Michael Bass
Optical Absorption, Depolarization, And Scatter Of Epitaxial Single-Crystal Chemical-Vapor-Deposited Diamond At 1.064 Μm, Giorgio Turri, Ying Chen, Michael Bass
Publications
No abstract provided.
Optical Properties Of Epitaxial Single-Crystal Chemical-Vapor-Deposited Diamond, Giorgio Turri, Ying Chen, Michael Bass, David Orchard, James E. Butler
Optical Properties Of Epitaxial Single-Crystal Chemical-Vapor-Deposited Diamond, Giorgio Turri, Ying Chen, Michael Bass, David Orchard, James E. Butler
Publications
Epitaxial single-crystal chemical-vapor-deposited diamond was obtained from Element Six Ltd. (Ascot, UK) and from Apollo Diamond (Boston, MA). Both companies provided 5 x 5 mm squares with thicknesses ranging from 0.5 to 1.5 mm. In addition, Element Six provided 10-mm-diameter disks with a thickness of 1.0 mm. The absorptance of all specimens at 1064 nm was measured by laser calorimetry, with good agreement between independent measurements at the University of Central Florida and at QinetiQ (Malvern, UK). Depolarization at 1064 nm and ultraviolet absorption properties are also reported.
Poisson-Boltzmann Calculations Of Nonspecific Salt Effects On Protein-Protein Binding Free Energies, Claudia Bertonati, Barry Honig, Emil Alexov
Poisson-Boltzmann Calculations Of Nonspecific Salt Effects On Protein-Protein Binding Free Energies, Claudia Bertonati, Barry Honig, Emil Alexov
Publications
The salt dependence of the binding free energy of five protein-protein hetero-dimers and two homo-dimers/tetramers was calculated from numerical solutions to the Poisson-Boltzmann equation. Overall, the agreement with experimental values is very good. In all cases except one involving the highly charged lactoglobulin homo-dimer, increasing the salt concentration is found both experimentally and theoretically to decrease the binding affinity. To clarify the source of salt effects, the salt-dependent free energy of binding is partitioned into screening terms and to self-energy terms that involve the interaction of the charge distribution of a monomer with its own ion atmosphere. In six of …
A Dyad Theory Of Hydrodynamics And Electrodynamics, Preston Jones
A Dyad Theory Of Hydrodynamics And Electrodynamics, Preston Jones
Publications
The dyadic calculus is developed in a form suitable for the description of physical relations in curved space. The 4-space equations of hydrodynamics and electrodynamics are constructed using this dyadic calculus. As a demonstration of the relationship between gravity and electrodynamics a time varying metric is shown to generate electromagnetic radiation.