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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Multidimensional Feature Engineering For Post-Translational Modification Prediction Problems, Norman Mapes Jr.
Multidimensional Feature Engineering For Post-Translational Modification Prediction Problems, Norman Mapes Jr.
Doctoral Dissertations
Protein sequence data has been produced at an astounding speed. This creates an opportunity to characterize these proteins for the treatment of illness. A crucial characterization of proteins is their post translational modifications (PTM). There are 20 amino acids coded by DNA after coding (translation) nearly every protein is modified at an amino acid level. We focus on three specific PTMs. First is the bonding formed between two cysteine amino acids, thus introducing a loop to the straight chain of a protein. Second, we predict which cysteines can generally be modified (oxidized). Finally, we predict which lysine amino acids are …
Leveraging Eye Structure And Motion To Build A Low-Power Wearable Gaze Tracking System, Addison Mayberry
Leveraging Eye Structure And Motion To Build A Low-Power Wearable Gaze Tracking System, Addison Mayberry
Doctoral Dissertations
Clinical studies have shown that features of a person's eyes can function as an effective proxy for cognitive state and neurological function. Technological advances in recent decades have allowed us to deepen this understanding and discover that the actions of the eyes are in fact very tightly coupled to the operation of the brain. Researchers have used camera-based eye monitoring technology to exploit this connection and analyze mental state across across many different metrics of interest. These range from simple things like attention and scene processing, to impairments such as a fatigue or substance use, and even significant mental disorders …