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Articles 1 - 7 of 7
Full-Text Articles in Physical Sciences and Mathematics
The Synthesis And Evaluation Of The Cardiovascular Activity Of Novel Imidazole Ring Systems, Joseph E. De Los Angeles
The Synthesis And Evaluation Of The Cardiovascular Activity Of Novel Imidazole Ring Systems, Joseph E. De Los Angeles
Chemistry & Biochemistry Theses & Dissertations
An investigation was undertaken to synthesize and evaluate the cardiovascular activity of two imidazole ring systems. Imidazoles with hypotensive activity would provide novel potential antihypertensive drugs. These novel structures may also find use as chemical probes in the study of the cardiovascular system and as prototypes for other potential cardiovascular agents.
The histamine derivative, 7,7-dipyridyl-4,5,6,7-tetrahydroimidazo-[4,5-c]pyridine (ligand l), was demonstrated to possess significant hypotensive activity in laboratory rats. A 15 mg/Kg dose of ligand 1 produces a statistically significant decrease in blood pressure when injected IP. This hypotensive effect is also associated with marked increase in heart rate. Although compound 1 …
Peroxo Complexes Of Vanadium(V) And Molybdenum(Vi) With Nicotine And Aspartic Acids, Sandra Jean Sheffield
Peroxo Complexes Of Vanadium(V) And Molybdenum(Vi) With Nicotine And Aspartic Acids, Sandra Jean Sheffield
Dissertations, Theses, and Masters Projects
No abstract provided.
The Synthesis Of Hindered Aliphatic Ketones For The Future Production Of Spiro [4.5] Decane Sesquiterpenes, Stephen Lee Hodges
The Synthesis Of Hindered Aliphatic Ketones For The Future Production Of Spiro [4.5] Decane Sesquiterpenes, Stephen Lee Hodges
Dissertations, Theses, and Masters Projects
No abstract provided.
Secondary Isotope Effects Of Nucleophilic Vinylic Substitution, Paul Frederick Drees
Secondary Isotope Effects Of Nucleophilic Vinylic Substitution, Paul Frederick Drees
Dissertations, Theses, and Masters Projects
No abstract provided.
The Stereospecific Synthesis Of Tetrahydropyrans And Tetrahydrofurans, Rhonda Carol Winstead
The Stereospecific Synthesis Of Tetrahydropyrans And Tetrahydrofurans, Rhonda Carol Winstead
Dissertations, Theses, and Masters Projects
No abstract provided.
Peroxo Complexes Of Molybdenum (Vi) And Vanadium (V) With Imidazole And Histidine, Jennifer Lisa Gundersen
Peroxo Complexes Of Molybdenum (Vi) And Vanadium (V) With Imidazole And Histidine, Jennifer Lisa Gundersen
Dissertations, Theses, and Masters Projects
No abstract provided.
Carbon Alkylation Of 2-Phenylthio-1,3-Cyclopentanediones, Karol Renee Parham
Carbon Alkylation Of 2-Phenylthio-1,3-Cyclopentanediones, Karol Renee Parham
Dissertations, Theses, and Masters Projects
No abstract provided.