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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Game-Based Learning In Science: Can Video Games Simplify Organic Chemistry?, Rachel Israel May 2021

Game-Based Learning In Science: Can Video Games Simplify Organic Chemistry?, Rachel Israel

Senior Honors Theses

Organic chemistry has been taught in the same way for decades, and students still have difficulty understanding and comprehending the subject material. Perhaps it is time to change the methods by which this subject is taught. Video games have been successfully used in education to create learning environments that increase student motivation and engagement as well as challenge students and promote collaboration. It is difficult for students to maintain a growth mindset in organic chemistry within the classroom. However across different genres, video games create a unique environment where an individual is encouraged to try again when they fail. This …


Biomedical Applications And Syntheses Of Selected Anthraquinone Dyes, Richard Sirard Apr 2021

Biomedical Applications And Syntheses Of Selected Anthraquinone Dyes, Richard Sirard

Senior Honors Theses

Anthraquinones are aromatic organic compounds that have multiple applications in the biomedical field. Some anthraquinone-based compounds are used as fluorophores to contrast cell nuclei while others act as chemotherapeutic agents. However, there are not many fluorescent anthraquinone cell stains currently available. In this study, commercially available anthraquinone dyes, in addition to other dye families and compounds, were reviewed for their unique properties, advantages, and drawbacks. The development and characterization of three novel anthraquinone fluorophores revealed promising photophysical characteristics, like large Stokes shifts. One of the compounds, RBS3, was chosen for fixed and live cell staining and exhibited desirable biomedical properties. …


Use Of Anthraquinone Derivatives And Methods Of Efficient Syntheses, Alex Crespo Apr 2021

Use Of Anthraquinone Derivatives And Methods Of Efficient Syntheses, Alex Crespo

Senior Honors Theses

While the bromination of aromatic compounds is a well-researched topic, AQ and hydroxy substituted AQ derivatives, with two carbonyl groups acting as strong deactivators for electrophilic substitution, are notoriously difficult to brominate.11 Although there are well defined ways to brominate an AQ or hydroxy substituted AQ dating back to 1921,12 in order to synthesize more complex AQ derivatives, a method for halogenating AQ derivatives already bonded to more complicated or unstable functional groups is needed in order for the compound to carry out desirable activities. This represents an area of great need in research. The purpose of this …